Publications by authors named "Andrew Hettle"

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The complete λ-carrageenan depolymerization cascade from a marine Pseudoalteromonad revealed by structural analysis of the enzymes.
Chelsea J Vickers, Andrew G Hettle, Joanne K Hobbs, Sarah Shapiro-Ward, Benjamin Pluvinage

J Biol Chem· October 2025

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Analysis of chondroitin degradation by components of a Bacteroides caccae polysaccharide utilization locus.
Bernadette Alvarez, Olivia F Canil, Kristin E Low, Andrew G Hettle, D Wade Abbott

J Biol Chem· July 2025

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A Fluorogenic Disaccharide Substrate for α-Mannosidases Enables High-Throughput Screening and Identification of an Inhibitor of the GH92 Virulence Factor from .
Sandeep Bhosale, Matthew C Deen, Cameron Proceviat, Andrew Hettle, Dana K Winter

ACS Chem Biol· August 2023

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Metabolism of a hybrid algal galactan by members of the human gut microbiome.
Craig S Robb, Joanne K Hobbs, Benjamin Pluvinage, Greta Reintjes, Leeann Klassen, Andrew G Hettle

Nat Chem Biol· May 2022

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Sulfatases: Critical Enzymes for Algal Polysaccharide Processing.
Andrew G Hettle, Chelsea J Vickers, Alisdair B Boraston

Front Plant Sci· April 2022

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The structure of a family 110 glycoside hydrolase provides insight into the hydrolysis of α-1,3-galactosidic linkages in λ-carrageenan and blood group antigens.
Bailey E McGuire, Andrew G Hettle, Chelsea Vickers, Dustin T King, David J Vocadlo

J Biol Chem· December 2020

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Insights into the κ/ι-carrageenan metabolism pathway of some marine species.
Andrew G Hettle, Joanne K Hobbs, Benjamin Pluvinage, Chelsea Vickers, Kento T Abe

Commun Biol· July 2020

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Clinical Mutations That Partially Activate the Stringent Response Confer Multidrug Tolerance in .
Duncan Bryson, Andrew G Hettle, Alisdair B Boraston, Joanne K Hobbs

Antimicrob Agents Chemother· February 2020

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Biochemical Reconstruction of a Metabolic Pathway from a Marine Bacterium Reveals Its Mechanism of Pectin Depolymerization.
Joanne K Hobbs, Andrew G Hettle, Chelsea Vickers, Alisdair B Boraston

Appl Environ Microbiol· January 2019

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The Molecular Basis of Polysaccharide Sulfatase Activity and a Nomenclature for Catalytic Subsites in this Class of Enzyme.
Andrew G Hettle, Chelsea Vickers, Craig S Robb, Feng Liu, Stephen G Withers

Structure· May 2018

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Properties of a family 56 carbohydrate-binding module and its role in the recognition and hydrolysis of β-1,3-glucan.
Andrew Hettle, Alexander Fillo, Kento Abe, Patricia Massel, Benjamin Pluvinage

J Biol Chem· October 2017

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