Publications by authors named "Andrew L Harris"

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Molecular permeation through large pore channels: computational approaches and insights.
Deepak Kumar, Andrew L Harris, Yun Lyna Luo

J Physiol· August 2025

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PANX1 hexamers work but cells prefer heptamers.
Andrew L Harris

J Gen Physiol· March 2025

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Large-pore connexin hemichannels function like molecule transporters independent of ion conduction.
Pablo S Gaete, Deepak Kumar, Cynthia I Fernandez, Juan M Valdez Capuccino, Aashish Bhatt, Andrew L Harris

Proc Natl Acad Sci U S A· August 2024

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Connexin Gap Junction Channels and Hemichannels: Insights from High-Resolution Structures.
Maciej Jagielnicki, Iga Kucharska, Brad C Bennett, Andrew L Harris, Mark Yeager

Biology (Basel)· April 2024

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Free energy and kinetics of cAMP permeation through connexin26 via applied voltage and milestoning.
Wenjuan Jiang, Yi-Chun Lin, Wesley Botello-Smith, Jorge E Contreras, Andrew L Harris

Biophys J· August 2021

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A novel voltage-clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels.
Pablo S Gaete, Mauricio A Lillo, William López, Yu Liu, Wenjuan Jiang, Andrew L Harris

J Gen Physiol· November 2020

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The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening.
Juan M Valdez Capuccino, Payal Chatterjee, Isaac E García, Wesley M Botello-Smith, Han Zhang, Andrew L Harris

J Gen Physiol· March 2019

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Electrical coupling and its channels.
Andrew L Harris

J Gen Physiol· December 2018

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Genomic instability induced in distant progeny of bystander cells depends on the connexins expressed in the irradiated cells.
Sonia M de Toledo, Manuela Buonanno, Andrew L Harris, Edouard I Azzam

Int J Radiat Biol· October 2017

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Intramolecular signaling in a cardiac connexin: Role of cytoplasmic domain dimerization.
Andrew J Trease, Juan M V Capuccino, Jorge Contreras, Andrew L Harris, Paul L Sorgen

J Mol Cell Cardiol· October 2017

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Endothelial cAMP deactivates ischemia-reperfusion-induced microvascular hyperpermeability via Rap1-mediated mechanisms.
Adam H Korayem, Patricio E Mujica, Haruo Aramoto, Ricardo G Durán, Prerna R Nepali, Andrew L Harris

Am J Physiol Heart Circ Physiol· July 2017

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Non-junctional Cx32 mediates anti-apoptotic and pro-tumor effects via epidermal growth factor receptor in human cervical cancer cells.
Yifan Zhao, Yongchang Lai, Hui Ge, Yunquan Guo, Xue Feng, Andrew L Harris

Cell Death Dis· May 2017

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Mechanism of gating by calcium in connexin hemichannels.
William Lopez, Jayalakshmi Ramachandran, Abdelaziz Alsamarah, Yun Luo, Andrew L Harris

Proc Natl Acad Sci U S A· December 2016

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Computational Studies of Molecular Permeation through Connexin26 Channels.
Yun Luo, Angelo R Rossi, Andrew L Harris

Biophys J· February 2016

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An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels.
Brad C Bennett, Michael D Purdy, Kent A Baker, Chayan Acharya, William E McIntire, Andrew L Harris

Nat Commun· January 2016

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Glutathione release through connexin hemichannels: Implications for chemical modification of pores permeable to large molecules.
Xuhui Tong, William Lopez, Jayalakshmi Ramachandran, Wafaa A Ayad, Yu Liu, Andrew L Harris

J Gen Physiol· September 2015

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Gap junctions modulate glioma invasion by direct transfer of microRNA.
Xiaoting Hong, Wun Chey Sin, Andrew L Harris, Christian C Naus

Oncotarget· June 2015

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Divalent regulation and intersubunit interactions of human connexin26 (Cx26) hemichannels.
William Lopez, Yu Liu, Andrew L Harris, Jorge E Contreras

Channels (Austin)· January 2015

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Motifs in the permeation pathway of connexin channels mediate voltage and Ca (2+) sensing.
Andrew L Harris, Jorge E Contreras

Front Physiol· June 2014

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Insights on the mechanisms of Ca(2+) regulation of connexin26 hemichannels revealed by human pathogenic mutations (D50N/Y).
William Lopez, Jorge Gonzalez, Yu Liu, Andrew L Harris, Jorge E Contreras

J Gen Physiol· July 2013

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Connexin 43 is involved in the generation of human-induced pluripotent stem cells.
Qiong Ke, Li Li, Bing Cai, Chang Liu, Yan Yang, Andrew L Harris

Hum Mol Genet· June 2013

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Human cell responses to ionizing radiation are differentially affected by the expressed connexins.
Narongchai Autsavapromporn, Sonia M De Toledo, Jean-Paul Jay-Gerin, Andrew L Harris, Edouard I Azzam

J Radiat Res· March 2013

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Gap junctions propagate opposite effects in normal and tumor testicular cells in response to cisplatin.
Xiaoting Hong, Qin Wang, Yan Yang, Suping Zheng, Xuhui Tong, Andrew L Harris

Cancer Lett· April 2012

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Monocyte-endothelial adhesion is modulated by Cx43-stimulated ATP release from monocytes.
Dongdong Yuan, Qin Wang, Dengpan Wu, Meiling Yu, Suzhi Zhang, Andrew L Harris

Biochem Biophys Res Commun· April 2012

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Molecular dynamics simulations of the Cx26 hemichannel: insights into voltage-dependent loop-gating.
Taekyung Kwon, Benoît Roux, Sunhwan Jo, Jeffery B Klauda, Andrew L Harris

Biophys J· March 2012

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