Publications by authors named "Andrew M Chan"

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Targeting the tyrosine kinase Src in endothelium attenuates inflammation and atherogenesis induced by disturbed flow.
Huanyu Ding, Minchun Jiang, Andrew M Chan, Yin Xia, Ronald C W Ma

Br J Pharmacol· October 2025

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Author Correction: SLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR function.
Mihyun Bae, Junyeop Daniel Roh, Youjoung Kim, Seong Soon Kim, Hye Min Han, Andrew M Chan

EMBO Mol Med· October 2024

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Astrocyte-specific knockout of YKL-40/Chi3l1 reduces Aβ burden and restores memory functions in 5xFAD mice.
Xiaoyan Zeng, Stanley K K Cheung, Mengqi Shi, Penelope M Y Or, Zhining Li, Andrew M Chan

J Neuroinflammation· December 2023

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Curaxin CBL0137 inhibits endothelial inflammation and atherogenesis via suppression of the Src-YAP signalling axis.
Huanyu Ding, Minchun Jiang, Chi Wai Lau, Jianfang Luo, Andrew M Chan

Br J Pharmacol· April 2023

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Neuropathological signatures revealed by transcriptomic and proteomic analysis in Pten-deficient mouse models.
Stanley K K Cheung, Jacinda Kwok, Penelope M Y Or, Chi Wai Wong, Bo Feng, Raymond C C Chang, Andrew M Chan

Sci Rep· April 2023

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Inhibition of PI3 kinase isoform p110α suppresses neuroblastoma growth and induces the reduction of Anaplastic Lymphoma Kinase.
Yue Guo, Donghao Guo, Shaoting Zhang, Yuan Zhang, Xiaoyan He, Andrew Man-Lok Chan

Cell Biosci· December 2022

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The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent transcriptional upregulation of hexokinase II in glioma.
Tian Liu, Yubing Wang, Yiwei Wang, Stanley Kwok-Kuen Cheung, Penelope Mei-Yu Or, Andrew M Chan

Cancer Lett· November 2022

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Functional analysis of the short splicing variant encoded by CHI3L1/YKL-40 in glioblastoma.
Mengqi Shi, Qianyun Ge, Xinrong Wang, Wenbin Diao, Ben Yang, Andrew Man-Lok Chan

Front Oncol· November 2022

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Endothelial nitric oxide synthase (eNOS)-NO signaling axis functions to promote the growth of prostate cancer stem-like cells.
Weijie Gao, Yuliang Wang, Shan Yu, Zhu Wang, Taiyang Ma, Andrew Man-Lok Chan, Franky Leung Chan

Stem Cell Res Ther· May 2022

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Tumour-derived substrate-adherent cells promote neuroblastoma survival through secreted trophic factors.
Jing Li, Yubing Wang, Lisha Li, Penelope M-Y Or, Chi Wai Wong, Andrew M Chan

Mol Oncol· August 2021

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SLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR function.
Mihyun Bae, Junyeop Daniel Roh, Youjoung Kim, Seong Soon Kim, Hye Min Han, Andrew M Chan

EMBO Mol Med· February 2021

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Autism-associated PTEN missense mutation leads to enhanced nuclear localization and neurite outgrowth in an induced pluripotent stem cell line.
Chi Wai Wong, Yubing Wang, Tian Liu, Lisha Li, Stanley Kwok Kuen Cheung, Raymond Chuen Chung Chang, Andrew M Chan

FEBS J· November 2020

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Multifaceted Regulation of PTEN Subcellular Distributions and Biological Functions.
Tian Liu, Yiwei Wang, Yubing Wang, Andrew M Chan

Cancers (Basel)· August 2019

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Homology-independent multiallelic disruption via CRISPR/Cas9-based knock-in yields distinct functional outcomes in human cells.
Chenzi Zhang, Xiangjun He, Yvonne K Kwok, Feng Wang, Junyi Xue, Andrew M Chan, Wai-Yee Chan

BMC Biol· December 2018

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Loss of tumor suppressor IGFBP4 drives epigenetic reprogramming in hepatic carcinogenesis.
Ying-Ying Lee, Myth Ts Mok, Wei Kang, Weiqin Yang, Wenshu Tang, Andrew M Chan

Nucleic Acids Res· September 2018

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Differential regulation of the pro-inflammatory biomarker, YKL-40/CHI3L1, by PTEN/Phosphoinositide 3-kinase and JAK2/STAT3 pathways in glioblastoma.
Yubing Wang, Chi Wai Wong, Mingfei Yan, Lisha Li, Tian Liu, Andrew Man-Lok Chan

Cancer Lett· August 2018

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PTEN PDZ-binding domain suppresses mammary carcinogenesis in the MMTV-PyMT breast cancer model.
Mingfei Yan, Yubing Wang, Chi Wai Wong, Penelope Mei-Yu Or, Kin Lok Wong, Andrew M Chan

Cancer Lett· August 2018

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Eriocalyxin B, a novel autophagy inducer, exerts anti-tumor activity through the suppression of Akt/mTOR/p70S6K signaling pathway in breast cancer.
Xunian Zhou, Grace Gar-Lee Yue, Andrew Man-Lok Chan, Stephen Kwok-Wing Tsui, Kwok-Pui Fung

Biochem Pharmacol· October 2017

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A thirty-year quest for a role of R-Ras in cancer: from an oncogene to a multitasking GTPase.
Wai Nam Liu, Mingfei Yan, Andrew M Chan

Cancer Lett· September 2017

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R-Ras Regulates Murine T Cell Migration and Intercellular Adhesion Molecule-1 Binding.
Xiaocai Yan, Mingfei Yan, Yihe Guo, Gobind Singh, Yuhong Chen, Andrew M Chan

PLoS One· July 2016

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Erratum to: Separation and Characterization of Epithelial and Mesenchymal-like Murine Mammary Tumor Cells Reveals Epithelial Cell Differentiation Plasticity and Enhanced Tumorigenicity of Epithelial-enriched Tumor Cells.
Katie A Palen, Weiqing Jing, James J Weber, Sara B Tilkens, Andrew M Chan

Cancer Microenviron· April 2016

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The genetic landscapes of inflammation-driven gastrointestinal tract cancers.
Yubing Wang, Mingfei Yan, Penelope Mei-Yu Or, Andrew Man-Lok Chan

Curr Pharm Des· March 2016

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PTEN recruitment controls synaptic and cognitive function in Alzheimer's models.
Shira Knafo, Cristina Sánchez-Puelles, Ernest Palomer, Igotz Delgado, Jonathan E Draffin, Andrew M Chan

Nat Neurosci· March 2016

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A CCRK-EZH2 epigenetic circuitry drives hepatocarcinogenesis and associates with tumor recurrence and poor survival of patients.
Hai Feng, Zhuo Yu, Yuan Tian, Ying-Ying Lee, May S Li, Andrew M L Chan, Henry L Y Chan

J Hepatol· May 2015

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An increase in tolerogenic dendritic cell and natural regulatory T cell numbers during experimental autoimmune encephalomyelitis in Rras-/- mice results in attenuated disease.
Avijit Ray, Sreemanti Basu, Nichole M Miller, Andrew M Chan, Bonnie N Dittel

J Immunol· June 2014

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