Publications by authors named "Andrew Midzak"

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mutations in rats and a human polymorphism impair the rate of steroid synthesis.
David R Owen, Jinjiang Fan, Enrico Campioli, Sathvika Venugopal, Andrew Midzak

Biochem J· November 2017

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Adrenal Mitochondria and Steroidogenesis: From Individual Proteins to Functional Protein Assemblies.
Andrew Midzak, Vassilios Papadopoulos

Front Endocrinol (Lausanne)· August 2016

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Steroidogenesis: The Classics and Beyond.
Andrew Midzak, Vassilios Papadopoulos

Steroids· November 2015

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Computational modeling and biological validation of novel non-steroidal ligands for the cholesterol recognition/interaction amino acid consensus (CRAC) motif of the mitochondrial translocator protein (TSPO).
Andrew S Midzak, Nagaraju Akula, Malena B Rone, Vassilios Papadopoulos

Pharmacol Res· September 2015

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2-Phenylimidazo[1,2-a]pyridine-containing ligands of the 18-kDa translocator protein (TSPO) behave as agonists and antagonists of steroidogenesis in a mouse leydig tumor cell line.
Andrew Midzak, Nunzio Denora, Valentino Laquintana, Annalisa Cutrignelli, Angela Lopedota

Eur J Pharm Sci· August 2015

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Translocator protein: pharmacology and steroidogenesis.
Andrew Midzak, Barry Zirkin, Vassilios Papadopoulos

Biochem Soc Trans· August 2015

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Translocator protein-mediated pharmacology of cholesterol transport and steroidogenesis.
Vassilios Papadopoulos, Yasaman Aghazadeh, Jinjiang Fan, Enrico Campioli, Barry Zirkin, Andrew Midzak

Mol Cell Endocrinol· June 2015

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Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation.
Jinjiang Fan, Enrico Campioli, Andrew Midzak, Martine Culty, Vassilios Papadopoulos

Proc Natl Acad Sci U S A· June 2015

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Steroidogenesis in MA-10 mouse Leydig cells is altered via fatty acid import into the mitochondria.
Malena B Rone, Andrew S Midzak, Daniel B Martinez-Arguelles, Jinjiang Fan, Xiaoying Ye

Biol Reprod· October 2014

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Binding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterols.
Andrew Midzak, Vassilios Papadopoulos

Traffic· September 2014

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Characterization of maleimide-based glycogen synthase kinase-3 (GSK-3) inhibitors as stimulators of steroidogenesis.
Hendra Gunosewoyo, Andrew Midzak, Irina N Gaisina, Emily V Sabath, Allison Fedolak

J Med Chem· June 2013

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Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormones.
Malena B Rone, Andrew S Midzak, Leeyah Issop, Georges Rammouz, Sathvika Jagannathan

Mol Endocrinol· November 2012

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Structure-activity relationship (SAR) analysis of a family of steroids acutely controlling steroidogenesis.
Andrew Midzak, Georges Rammouz, Vassilios Papadopoulos

Steroids· November 2012

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Identification of small-molecule inhibitors of the steroidogenic acute regulatory protein (STARD1) by structure-based design.
Nagaraju Akula, Andrew Midzak, Laurent Lecanu, Vassilios Papadopoulos

Bioorg Med Chem Lett· June 2012

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ATP synthesis, mitochondrial function, and steroid biosynthesis in rodent primary and tumor Leydig cells.
Andrew S Midzak, Haolin Chen, Miguel A Aon, Vassilios Papadopoulos, Barry R Zirkin

Biol Reprod· May 2011

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Mitochondrial protein import and the genesis of steroidogenic mitochondria.
Andrew Midzak, Malena Rone, Yassaman Aghazadeh, Martine Culty, Vassilios Papadopoulos

Mol Cell Endocrinol· April 2011

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Novel androstenetriol interacts with the mitochondrial translocator protein and controls steroidogenesis.
Andrew Midzak, Nagaraju Akula, Laurent Lecanu, Vassilios Papadopoulos

J Biol Chem· March 2011

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Leydig cell aging and the mechanisms of reduced testosterone synthesis.
Andrew S Midzak, Haolin Chen, Vassilios Papadopoulos, Barry R Zirkin

Mol Cell Endocrinol· February 2009

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Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer.
J Harrison Howard, Andrey Frolov, Ching-Wei D Tzeng, Ashley Stewart, Andrew Midzak

Cancer Biol Ther· January 2009

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Effect of myxothiazol on Leydig cell steroidogenesis: inhibition of luteinizing hormone-mediated testosterone synthesis but stimulation of basal steroidogenesis.
Andrew S Midzak, June Liu, Barry R Zirkin, Haolin Chen

Endocrinology· June 2007

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