Publications by authors named "Andrew Nortcliffe"

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Collaborative Synthesis for Neglected Diseases through the Open Synthesis Network: Structure-Activity Relationships of Arylaminopyrazoles as Chagas Disease Treatments.
Zigli Abdulai, Natasha Agbo, Jonathan I Anderson, Faye Astley, Brian Chan, Andrew Nortcliffe

ACS Infect Dis· September 2025

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Iodoetherification as a strategy towards sp-rich scaffolds for drug discovery.
Lydia Barnes, Timothy N Birkinshaw, Aaron J Senior, Oscar Siles Brügge, William Lewis, Andrew Nortcliffe

Bioorg Med Chem· March 2024

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Design, and synthesis of selectively anticancer 4-cyanophenyl substituted thiazol-2-ylhydrazones.
Hasnain Mehmood, Mustapha Musa, Simon Woodward, Md Shahadat Hossan, Tracey D Bradshaw, Andrew Nortcliffe

RSC Adv· November 2022

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Iridium-catalysed C-H borylation of β-aryl-aminopropionic acids.
Henry Robinson, Joe Stillibrand, Klemensas Simelis, Simon J F Macdonald, Andrew Nortcliffe

Org Biomol Chem· September 2020

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Free-Wilson Analysis of Comprehensive Data on Phosphoinositide-3-kinase (PI3K) Inhibitors Reveals Importance of -Methylation for PI3Kδ Activity.
Lydia Barnes, Hollie Blaber, David T K Brooks, Lewis Byers, Daniel Buckley, Andrew Nortcliffe

J Med Chem· November 2019

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Synthesis of Highly Substituted 1,2-Diazetidin-3-ones, Small-Ring Scaffolds for Drug Discovery.
Marilia S Santos, Andrew Nortcliffe, William Lewis, Tracey D Bradshaw, Christopher J Moody

Chemistry· June 2018

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Densely functionalised spirocyclic oxetane-piperidine scaffolds for drug discovery.
Gemma C Geary, Andrew Nortcliffe, Christopher A Pearce, Daniel Hamza, Geraint Jones

Bioorg Med Chem· February 2018

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C-H Insertion as a Key Step to Spiro-Oxetanes, Scaffolds for Drug Discovery.
Simon M Nicolle, Andrew Nortcliffe, Hannah E Bartrum, William Lewis, Christopher J Hayes

Chemistry· October 2017

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Synthesis of 4-aminotetrahydropyran scaffolds for drug discovery.
Andrew Nortcliffe, Gavin D S Milne, Daniel Hamza, Christopher J Moody

Bioorg Med Chem· April 2017

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Seven-membered ring scaffolds for drug discovery: Access to functionalised azepanes and oxepanes through diazocarbonyl chemistry.
Andrew Nortcliffe, Christopher J Moody

Bioorg Med Chem· June 2015

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Synthesis and biological evaluation of nitric oxide-donating analogues of sulindac for prostate cancer treatment.
Andrew Nortcliffe, Alexander G Ekstrom, James R Black, James A Ross, Fouad K Habib

Bioorg Med Chem· January 2014

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Novel amino acids: synthesis of furoxan and sydnonimine containing amino acids and peptides as potential nitric oxide releasing motifs.
Andrew Nortcliffe, Nigel P Botting, David O'Hagan

Org Biomol Chem· July 2013

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