Publications by authors named "Andrew Skaff"

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Tracking hemopexin intracellularly and defining hemopexin protein "interactomes" in human immune and liver cell models.
Bryan Rose, David Moore, Jeff Eskew, Roberto Vanacore, Steve D Hartson, D Andrew Skaff

Front Physiol· December 2025

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Targeting the Initiator Protease of the Classical Pathway of Complement Using Fragment-Based Drug Discovery.
Blake R Rushing, Denise L Rohlik, Sourav Roy, D Andrew Skaff, Brandon L Garcia

Molecules· September 2020

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Identification of oxidative modifications of hemopexin and their predicted physiological relevance.
Peter Hahl, Rachel Hunt, Edward S Bjes, Andrew Skaff, Andrew Keightley

J Biol Chem· August 2017

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Identification of C3b-Binding Small-Molecule Complement Inhibitors Using Cheminformatics.
Brandon L Garcia, D Andrew Skaff, Arindam Chatterjee, Anders Hanning, John K Walker

J Immunol· May 2017

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A One Health overview, facilitating advances in comparative medicine and translational research.
Cheryl Stroud, Igor Dmitriev, Elena Kashentseva, Jeffrey N Bryan, David T Curiel, Andrew Skaff

Clin Transl Med· August 2016

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Active site binding modes of inhibitors of Staphylococcus aureus mevalonate diphosphate decarboxylase from docking and molecular dynamics simulations.
James K Addo, D Andrew Skaff, Henry M Miziorko

J Mol Model· January 2016

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Inhibition of bacterial mevalonate diphosphate decarboxylase by eriochrome compounds.
D Andrew Skaff, William J McWhorter, Brian V Geisbrecht, Gerald J Wyckoff, Henry M Miziorko

Arch Biochem Biophys· January 2015

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Identification in Haloferax volcanii of phosphomevalonate decarboxylase and isopentenyl phosphate kinase as catalysts of the terminal enzyme reactions in an archaeal alternate mevalonate pathway.
John C Vannice, D Andrew Skaff, Andrew Keightley, James K Addo, Gerald J Wyckoff

J Bacteriol· March 2014

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Expression in Haloferax volcanii of 3-hydroxy-3-methylglutaryl coenzyme A synthase facilitates isolation and characterization of the active form of a key enzyme required for polyisoprenoid cell membrane biosynthesis in halophilic archaea.
John C VanNice, D Andrew Skaff, Gerald J Wyckoff, Henry M Miziorko

J Bacteriol· September 2013

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Biochemical and structural basis for inhibition of Enterococcus faecalis hydroxymethylglutaryl-CoA synthase, mvaS, by hymeglusin.
D Andrew Skaff, Kasra X Ramyar, William J McWhorter, Michael L Barta, Brian V Geisbrecht

Biochemistry· June 2012

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Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase.
Lee F Peng, Esperance A K Schaefer, Nicole Maloof, Andrew Skaff, Andrew Berical

J Infect Dis· August 2011

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Crystal structures of Staphylococcus epidermidis mevalonate diphosphate decarboxylase bound to inhibitory analogs reveal new insight into substrate binding and catalysis.
Michael L Barta, D Andrew Skaff, William J McWhorter, Timothy J Herdendorf, Henry M Miziorko

J Biol Chem· July 2011

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A visible wavelength spectrophotometric assay suitable for high-throughput screening of 3-hydroxy-3-methylglutaryl-CoA synthase.
D Andrew Skaff, Henry M Miziorko

Anal Biochem· January 2010

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Glucose 6-phosphate release of wild-type and mutant human brain hexokinases from mitochondria.
D Andrew Skaff, Chang Sup Kim, Henry J Tsai, Richard B Honzatko, Herbert J Fromm

J Biol Chem· November 2005

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