Publications by authors named "Andrew Sproul"

Claim this Profile
G
Generation of hiPSC-Derived Brain Microvascular Endothelial Cells Using Directed Differentiation and Transcriptional Reprogramming.
Aomeng Cui, Ronak Patel, Patrick Bosco, Uğur Akcan, Emily Richters, Andrew A Sproul

Arterioscler Thromb Vasc Biol· January 2026

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High throughput identification of genetic regulators of microglial inflammatory processes in Alzheimer's disease.
Christopher L Cardona, Lai Wei, Joonwon Kim, Ellen Angeles, Gunjandeep Singh, Andrew A Sproul

J Neuroinflammation· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
HDAC inhibitors engage MITF and the disease-associated microglia signature to enhance amyloid β uptake.
Verena Haage, John F Tuddenham, Alex Bautista, Frankie Garcia G, Charles C White, Andrew A Sproul

Brain Behav Immun· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A proteogenomic tool uncovers protein markers for human microglial states.
Verena Haage, Alex R Bautista, John Tuddenham, Victoria Marshe, Rebecca Chiu, Andrew A Sproul

bioRxiv· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High throughput identification of genetic regulators of microglial inflammatory processes in Alzheimer's disease.
Christopher L Cardona, Lai Wei, Joonwon Kim, Ellen Angeles, Gunjandeep Singh, Andrew A Sproul

bioRxiv· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Reduced may protect against Alzheimer's disease by lowering microglial pro-inflammatory responses via modulation of JNK and NFkB signaling.
Ronak Patel, Rong Cheng, Christopher L Cardona, Ellen Angeles, Gunjandeep Singh, Andrew A Sproul

bioRxiv· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Generating iAstrocytes From Human Induced Pluripotent Stem Cells by Combining Low-Density Passaging of Neural Progenitor Cells and Transcription Factor NFIA Transdifferentiation.
Patrick Bosco, Ugur Akcan, Damian Williams, Heather M Buchanan, Dritan Agalliu, Andrew A Sproul

Curr Protoc· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
HDAC Inhibitors recapitulate Human Disease-Associated Microglia Signatures .
Verena Haage, John F Tuddenham, Alex Bautista, Charles C White, Frankie Garcia, Andrew A Sproul

bioRxiv· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Generation of hiPSC-derived brain microvascular endothelial cells using a combination of directed differentiation and transcriptional reprogramming strategies.
Aomeng Cui, Ronak Patel, Patrick Bosco, Ugur Akcan, Emily Richters, Andrew A Sproul

bioRxiv· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
X
Xenografted human iPSC-derived neurons with the familial Alzheimer's disease APP mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator.
Wenhui Qu, Matti Lam, Julie J McInvale, Jason A Mares, Sam Kwon, Andrew A Sproul

Acta Neuropathol· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons.
Osama Al-Dalahmah, Matti Lam, Julie J McInvale, Wenhui Qu, Trang Nguyen, Andrew A Sproul

Cell Stem Cell· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A pharmacological toolkit for human microglia identifies Topoisomerase I inhibitors as immunomodulators for Alzheimer's disease.
Verena Haage, John F Tuddenham, Natacha Comandante-Lou, Alex Bautista, Anna Monzel, Andrew A Sproul

bioRxiv· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Z
ZCCHC17 Modulates Neuronal RNA Splicing and Supports Cognitive Resilience in Alzheimer's Disease.
Anne Marie W Bartosch, Elliot H H Youth, Shania Hansen, Yiyang Wu, Heather M Buchanan, Andrew A Sproul

J Neurosci· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Z
ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease.
Anne Marie W Bartosch, Elliot H H Youth, Shania Hansen, Maria E Kaufman, Harrison Xiao, Andrew A Sproul

bioRxiv· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation.
Yoon A Kim, Tohid Siddiqui, Jennifer Blaze, Mehmet Ilyas Cosacak, Tristan Winters, Andrew A Sproul

Acta Neuropathol· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics.
Elodie Bosc, Julie Anastasie, Feryel Soualmia, Pascale Coric, Ju Youn Kim, Andrew A Sproul

Cell Death Dis· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy.
Annie Lee, Chandana Kondapalli, Daniel M Virga, Tommy L Lewis, So Yeon Koo, Andrew Sproul

Nat Commun· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Crosstalk between acetylation and the tyrosination/detyrosination cycle of α-tubulin in Alzheimer's disease.
José Martínez-Hernández, Julie Parato, Aditi Sharma, Jean-Marc Soleilhac, Xiaoyi Qu, Andrew Sproul

Front Cell Dev Biol· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Tubulin tyrosination regulates synaptic function and is disrupted in Alzheimer's disease.
Leticia Peris, Julie Parato, Xiaoyi Qu, Jean Marc Soleilhac, Fabien Lanté, Andrew Sproul

Brain· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Efficient Derivation of Excitatory and Inhibitory Neurons from Human Pluripotent Stem Cells Stably Expressing Direct Reprogramming Factors.
Saera Song, Archana Ashok, Damian Williams, Maria Kaufman, Karen Duff, Andrew Sproul

Curr Protoc· June 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate.
Tyler M Lu, Sean Houghton, Tarig Magdeldin, José Gabriel Barcia Durán, Andrew P Minotti, Andrew Sproul

Proc Natl Acad Sci U S A· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Alzheimer's disease-associated C99 fragment of APP regulates cellular cholesterol trafficking.
Jorge Montesinos, Marta Pera, Delfina Larrea, Cristina Guardia-Laguarta, Rishi R Agrawal, Andrew A Sproul

EMBO J· October 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Autophagy Induction by Bexarotene Promotes Mitophagy in Presenilin 1 Familial Alzheimer's Disease iPSC-Derived Neural Stem Cells.
Patricia Martín-Maestro, Andrew Sproul, Hector Martinez, Dominik Paquet, Meri Gerges

Mol Neurobiol· December 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Alzheimer's disease and the autophagic-lysosomal system.
Kyung Min Chung, Nancy Hernández, Andrew A Sproul, Wai Haung Yu

Neurosci Lett· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage.
Jichao Sun, Jared Carlson-Stevermer, Utpal Das, Minjie Shen, Marion Delenclos, Andrew A Sproul

Nat Commun· January 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis