Publications by authors named "Andrew Varley"

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Divergent Delivery and Expression Kinetics of Lipid and Polymeric Nanoparticles across mRNA Modalities.
Irafasha C Casmil, Josh J Friesen, Nuthan V Bathula, Anneke Strumpel, Chia Hao Ho, Andrew J Varley

Adv Sci (Weinh)· October 2025

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Zwitterionic Hydrogels: From Synthetic Design to Biomedical Applications.
Linran Gao, Andrew Varley, Hui Gao, Bowen Li, Xiaohui Li

Langmuir· February 2025

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A Reverse Transcription Nucleic-Acid-Based Barcoding System for Measurement of Lipid Nanoparticle mRNA Delivery.
Kevin C Wang, Tiana L Young, Jingan Chen, Shannon N Tsai, Yue Xu, Andrew J Varley

ACS Bio Med Chem Au· February 2025

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Tumor-Tailored Ionizable Lipid Nanoparticles Facilitate IL-12 Circular RNA Delivery for Enhanced Lung Cancer Immunotherapy.
Shufen Xu, Yue Xu, Nicholas C Solek, Jingan Chen, Fanglin Gong, Andrew James Varley

Adv Mater· July 2024

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Accelerating ionizable lipid discovery for mRNA delivery using machine learning and combinatorial chemistry.
Bowen Li, Idris O Raji, Akiva G R Gordon, Lizhuang Sun, Theresa M Raimondo, Andrew Varley

Nat Mater· July 2024

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AGILE platform: a deep learning powered approach to accelerate LNP development for mRNA delivery.
Yue Xu, Shihao Ma, Haotian Cui, Jingan Chen, Shufen Xu, Andrew Varley

Nat Commun· July 2024

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Combinatorial design of ionizable lipid nanoparticles for muscle-selective mRNA delivery with minimized off-target effects.
Jingan Chen, Yue Xu, Muye Zhou, Shufen Xu, Andrew James Varley

Proc Natl Acad Sci U S A· December 2023

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Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing.
Bowen Li, Rajith Singh Manan, Shun-Qing Liang, Akiva Gordon, Allen Jiang, Andrew Varley

Nat Biotechnol· October 2023

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Synthesis of 5'-fluorophosphate-modified short-interfering RNAs.
Andrew Varley, Jean-Paul Desaulniers

Nucleosides Nucleotides Nucleic Acids· March 2023

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SiRNAs with Neutral Phosphate Triester Hydrocarbon Tails Exhibit Carrier-Free Gene-Silencing Activity.
Matthew L Hammill, Kouta Tsubaki, Lidya Salim, Andrew J Varley, Ifrodet Giorgees

ACS Med Chem Lett· April 2022

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Building siRNAs with Cubes: Synthesis and Evaluation of Cubane-Modified siRNAs.
Matthew L Hammill, Lidya Salim, Kouta Tsubaki, Andrew J Varley, Mitsuru Kitamura

Chembiochem· October 2021

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Chemical strategies for strand selection in short-interfering RNAs.
Andrew J Varley, Jean-Paul Desaulniers

RSC Adv· January 2021

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Effects of Chemical Modifications on siRNA Strand Selection in Mammalian Cells.
Andrew J Varley, Matthew L Hammill, Lidya Salim, Jean-Paul Desaulniers

Nucleic Acid Ther· August 2020

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Synthesis and Evaluation of Neutral Phosphate Triester Backbone-Modified siRNAs.
Kouta Tsubaki, Matthew L Hammill, Andrew J Varley, Mitsuru Kitamura, Tatsuo Okauchi

ACS Med Chem Lett· July 2020

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Utilizing the Ethylene-releasing Compound, 2-Chloroethylphosphonic Acid, as a Tool to Study Ethylene Response in Bacteria.
Richard V Augimeri, Andrew J Varley, Janice L Strap

J Vis Exp· November 2016

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Establishing a Role for Bacterial Cellulose in Environmental Interactions: Lessons Learned from Diverse Biofilm-Producing Proteobacteria.
Richard V Augimeri, Andrew J Varley, Janice L Strap

Front Microbiol· December 2015

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FlyMine: an integrated database for Drosophila and Anopheles genomics.
Rachel Lyne, Richard Smith, Kim Rutherford, Matthew Wakeling, Andrew Varley

Genome Biol· February 2008

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