Publications by authors named "Andriy Luzhetskyy"

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Heterologous biosynthetic crosstalk with the native mansouramycin cluster in Del14 reveals unexpected metabolites.
Marc Stierhof, Liliya Horbal, Patrick Oberhäuser, Anja Palusczak, Peyton Cox, Andriy Luzhetskyy

RSC Chem Biol· December 2025

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Metabolic engineering of Streptomyces explomaris for increased production of the reverse antibiotic nybomycin.
Wei Shu, Julian Stegmüller, Marta Rodriguez-Estevez, Christian Rückert-Reed, Jörn Kalinowski, Andriy Luzhetskyy

Microb Cell Fact· October 2025

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as a versatile host platform for heterologous production of microbial natural products.
Constanze Lasch, Maksym Myronovskyi, Andriy Luzhetskyy

Nat Prod Rep· September 2025

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Gene amir_2071 of Actinosynnema mirum DSM 43827 encodes a dimethylallyltryptophan synthase superfamily protein responsible for the production of prenylated tyrosine.
Sofiia Melnyk, Yuriy Rebets, Dmytro Bratiichuk, Andriy Luzhetskyy, Bohdan Ostash

Folia Microbiol (Praha)· August 2025

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Identification and heterologous expression of an NRPS biosynthetic gene cluster responsible for the production of the pyrazinones Ichizinone A, B and C.
Patrick Oberhäuser, Maksym Myronovskyi, Marc Stierhof, Oleksandr Gromyko, Andriy Luzhetskyy

Microb Cell Fact· June 2025

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Gromomycins: An Unprecedented Class of Triterpene Antibiotics Produced by a Novel Biosynthetic Pathway.
Stepan Tistechok, Dmytro Bratiichuk, Hilda Sucipto, Nils Gummerlich, Marc Stierhof, Andriy Luzhetskyy

Angew Chem Int Ed Engl· May 2025

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Description of sp. nov., isolated from the coastal soil rhizosphere of and reclassification of as a later heterotypic synonym of .
Wei Shu, Christian Rückert-Reed, Olexandr Gromyko, Stepan Tistechok, Jörn Kalinowski, Andriy Luzhetskyy

Int J Syst Evol Microbiol· May 2025

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Uncovering the genetic basis of antiviral polyketide limocrocin biosynthesis through heterologous expression.
Sofiia Melnyk, Marc Stierhof, Dmytro Bratiichuk, Franziska Fries, Rolf Müller, Andriy Luzhetskyy

Microb Cell Fact· January 2025

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An Improved Transformation-Associated Recombination Cloning Approach for Direct Capturing of Natural Product Biosynthetic Gene Clusters.
Olena Kurylenko, Anja Palusczak, Andriy Luzhetskyy, Yuriy Rebets

Microb Biotechnol· December 2024

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Systems metabolic engineering of the primary and secondary metabolism of Streptomyces albidoflavus enhances production of the reverse antibiotic nybomycin against multi-resistant Staphylococcus aureus.
Julian Stegmüller, Marta Rodríguez Estévez, Wei Shu, Lars Gläser, Maksym Myronovskyi, Andriy Luzhetskyy

Metab Eng· January 2024

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Discovery and overproduction of novel highly bioactive pamamycins through transcriptional engineering of the biosynthetic gene cluster.
Nikolas Eckert, Yuriy Rebets, Lilya Horbal, Josef Zapp, Jennifer Herrmann, Andriy Luzhetskyy

Microb Cell Fact· November 2023

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Heterologous Production and Biosynthesis of Threonine-16:0dioic acids with a Hydroxamate Moiety.
Marc Stierhof, Maksym Myronovskyi, Josef Zapp, Andriy Luzhetskyy

J Nat Prod· October 2023

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Systems biology of industrial oxytetracycline production in Streptomyces rimosus: the secrets of a mutagenized hyperproducer.
Selma Beganovic, Christian Rückert-Reed, Hilda Sucipto, Wei Shu, Lars Gläser, Andriy Luzhetskyy

Microb Cell Fact· October 2023

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Diversity and bioactive potential of Actinomycetia from the rhizosphere soil of Juniperus excelsa.
Stepan Tistechok, Ivan Roman, Victor Fedorenko, Andriy Luzhetskyy, Oleksandr Gromyko

Folia Microbiol (Praha)· August 2023

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Development of a Streptomyces-based system for facile thioholgamide library generation and analysis.
Maria Lopatniuk, Florian Riedel, Julia Wildfeuer, Marc Stierhof, Charlotte Dahlem, Andriy Luzhetskyy

Metab Eng· July 2023

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Properties of Multidrug-Resistant Mutants Derived from Heterologous Expression Chassis Strain J1074.
Borys Dolya, Olena Hryhorieva, Khrystyna Sorochynska, Maria Lopatniuk, Iryna Ostash, Andriy Luzhetskyy

Microorganisms· April 2023

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Mutations within gene XNR_2147 for TetR-like protein enhance lincomycin resistance and endogenous specialized metabolism of Streptomyces albus J1074.
Vasylyna-Marta Tseduliak, Borys Dolia, Iryna Ostash, Maria Lopatniuk, Tobias Busche, Andriy Luzhetskyy

J Appl Genet· February 2023

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Furaquinocins K and L: Novel Naphthoquinone-Based Meroterpenoids from sp. Je 1-369.
Stepan Tistechok, Marc Stierhof, Maksym Myronovskyi, Josef Zapp, Oleksandr Gromyko, Andriy Luzhetskyy

Antibiotics (Basel)· November 2022

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Flavacol and Its Novel Derivative 3--Hydroxy Flavacol from sp. Pv 4-95 after the Expression of Heterologous AdpA.
Stepan Tistechok, Marc Stierhof, Anna Kachor, Maksym Myronovskyi, Oleksandr Gromyko, Andriy Luzhetskyy

Microorganisms· November 2022

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Scandium-microorganism interactions in new biotechnologies.
Vasyl Syrvatka, Andrii Rabets, Oleksandr Gromyko, Andriy Luzhetskyy, Victor Fedorenko

Trends Biotechnol· September 2022

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Screening of Thiopeptide-Producing Streptomycetes Isolated From the Rhizosphere Soil of Juniperus excelsa.
Stepan Tistechok, Maksym Myronovskyi, Victor Fedorenko, Andriy Luzhetskyy, Oleksandr Gromyko

Curr Microbiol· September 2022

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Revealing Genome-Based Biosynthetic Potential of sp. BR123 Isolated from Sunflower Rhizosphere with Broad Spectrum Antimicrobial Activity.
Neelma Ashraf, Sana Zafar, Roman Makitrynskyy, Andreas Bechthold, Dieter Spiteller, Andriy Luzhetskyy

Antibiotics (Basel)· August 2022

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Miramides A-D: Identification of Detoxin-like Depsipeptides after Heterologous Expression of a Hybrid NRPS-PKS Gene Cluster from Lu17588.
Constanze Paulus, Maksym Myronovskyi, Josef Zapp, Marta Rodríguez Estévez, Maria Lopatniuk, Andriy Luzhetskyy

Microorganisms· August 2022

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Novel Biosynthetic Route to the Isoquinoline Scaffold.
Hui Shuai, Maksym Myronovskyi, Birgit Rosenkränzer, Constanze Paulus, Suvd Nadmid, Andriy Luzhetskyy

ACS Chem Biol· March 2022

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Total In Vitro Biosynthesis of the Thioamitide Thioholgamide and Investigation of the Pathway.
Asfandyar Sikandar, Maria Lopatniuk, Andriy Luzhetskyy, Rolf Müller, Jesko Koehnke

J Am Chem Soc· March 2022

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