Publications by authors named "Angel Amesty"

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Exploring the anti-inflammatory activity of fupenzic acid using network pharmacology and experimental validation.
Djoudi Boukerouis, Irene Cuadrado, Nadjet Debbache Benaida, Ana Estévez-Braun, Beatriz de Las Heras, Angel Amesty

Sci Rep· April 2025

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Synthesis, Biological Activity, and Molecular-Docking Studies of New Brassinosteroid Analogs.
María Nuñez, Yaowei Wang, Eugenia Russinova, Ana Estévez-Braun, Angel Amesty

Int J Mol Sci· September 2024

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1,2,3-Triazole-totarol conjugates as potent PIP5K1α lipid kinase inhibitors.
Samer Haidar, Ángel Amesty, Sandra Oramas-Royo, Claudia Götz, Ehab El-Awaad

Bioorg Med Chem· May 2024

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Methyl esters of 23,24-Dinor-5α-cholan-22-oic acids as brassinosteroid Analogues. Synthesis, evaluation of plant growth promoting activity and Molecular docking.
P Franco Cimino, G María Núñez, Anielka Rosado-Abón, Ángel Amesty, Ana Estévez-Braun

Steroids· August 2023

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Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors.
Laura González-Cofrade, Jack P Green, Irene Cuadrado, Ángel Amesty, Sandra Oramas-Royo

Bioorg Chem· March 2023

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Labdane conjugates protect cardiomyocytes from doxorubicin-induced cardiotoxicity.
Irene Cuadrado, Sandra Oramas-Royo, Laura González-Cofrade, Ángel Amesty, Sonsoles Hortelano

Drug Dev Res· February 2023

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Flavonoids from Species as Promising Antiprotozoal Agents against . Structure-Activity Relationship and Drug-Likeness Studies.
Juan C Ticona, Pablo Bilbao-Ramos, Ángel Amesty, Ninoska Flores, M Auxiliadora Dea-Ayuela

Pharmaceuticals (Basel)· November 2022

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Discovery of Highly Functionalized 5-hydroxy-2-pyrrol-2-ones That Exhibit Antiestrogenic Effects in Breast and Endometrial Cancer Cells and Potentiate the Antitumoral Effect of Tamoxifen.
Miguel Guerra-Rodríguez, Priscila López-Rojas, Ángel Amesty, Haidée Aranda-Tavío, Yeray Brito-Casillas

Cancers (Basel)· October 2022

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Dehydroisohispanolone as a Promising NLRP3 Inhibitor Agent: Bioevaluation and Molecular Docking.
Laura González-Cofrade, Irene Cuadrado, Ángel Amesty, Ana Estévez-Braun, Beatriz de Las Heras

Pharmaceuticals (Basel)· July 2022

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Design, Semisynthesis, and Estrogenic Activity of Lignan Derivatives from Natural Dibenzylbutyrolactones.
Priscila López-Rojas, Ángel Amesty, Miguel Guerra-Rodríguez, Yeray Brito-Casillas, Borja Guerra

Pharmaceuticals (Basel)· May 2022

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JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic myelogenous leukemia.
Haidée Aranda-Tavío, Carlota Recio, Pedro Martín-Acosta, Miguel Guerra-Rodríguez, Yeray Brito-Casillas, Angel Amesty

Biomed Pharmacother· December 2021

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Synthesis and Fungicidal Activity of Hydrated Geranylated Phenols against .
Mauricio Soto, Ana Estevez-Braun, Ángel Amesty, Julia Kluepfel, Susana Restrepo

Molecules· November 2021

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Modular Synthesis and Antiproliferative Activity of New Dihydro-1-pyrazolo[1,3-]pyridine Embelin Derivatives.
Pedro Martín-Acosta, Ángel Amesty, Miguel Guerra-Rodríguez, Borja Guerra, Leandro Fernández-Pérez

Pharmaceuticals (Basel)· October 2021

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: A Novel Tamoxifen Derivative Endowed with Antiestrogenic, Fluorescent, and Photosensitizer Properties.
Mario Díaz, Fernando Lobo, Dácil Hernández, Ángel Amesty, Catalina Valdés-Baizabal

Int J Mol Sci· May 2021

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Withanolide-Type Steroids from as Potential Anti-Leukemic Agents.
Laila M Moujir, Gabriel G Llanos, Liliana Araujo, Angel Amesty, Isabel L Bazzocchi

Molecules· December 2020

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Development of an in vitro screening assay for PIP5K1α lipid kinase and identification of potent inhibitors.
Katja Strätker, Samer Haidar, Ángel Amesty, Ehab El-Awaad, Claudia Götz

FEBS J· July 2020

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Dehydrohispanolone Derivatives Attenuate the Inflammatory Response through the Modulation of Inflammasome Activation.
Laura González-Cofrade, Sandra Oramas-Royo, Irene Cuadrado, Ángel Amesty, Sonsoles Hortelano

J Nat Prod· July 2020

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Efficient Multicomponent Synthesis of Diverse Antibacterial Embelin-Privileged Structure Conjugates.
Pedro Martín-Acosta, Rosalyn Peña, Gabriela Feresin, Alejandro Tapia, Isabel Lorenzo-Castrillejo, Ángel Amesty

Molecules· July 2020

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Design, synthesis and biological evaluation of new embelin derivatives as CK2 inhibitors.
Sandra Oramas-Royo, Samer Haidar, Ángel Amesty, Pedro Martín-Acosta, Gabriela Feresin

Bioorg Chem· January 2020

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Metal Complexes of Natural Product Like-compounds with Antitumor Activity.
Beatriz L Heras, Ángel Amesty, Ana Estévez-Braun, Sonsoles Hortelano

Anticancer Agents Med Chem· November 2019

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Synthesis and Antiplasmodial Activity of 1,2,3-Triazole-Naphthoquinone Conjugates.
Sandra Oramas-Royo, Priscila López-Rojas, Ángel Amesty, David Gutiérrez, Ninoska Flores

Molecules· October 2019

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α-Hispanolol Induces Apoptosis and Suppresses Migration and Invasion of Glioblastoma Cells Likely Downregulation of MMP-2/9 Expression and p38MAPK Attenuation.
Vanesa Sánchez-Martín, Lidia Jiménez-García, Sandra Herranz, Alfonso Luque, Paloma Acebo, Ángel Amesty

Front Pharmacol· September 2019

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Expanding the Chemical Space of Withaferin A by Incorporating Silicon To Improve Its Clinical Potential on Human Ovarian Carcinoma Cells.
Nayra R Perestelo, Gabriel G Llanos, Carolina P Reyes, Angel Amesty, Kartheek Sooda

J Med Chem· May 2019

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A Novel Naphthoquinone-Coumarin Hybrid That Inhibits BCR-ABL1-STAT5 Oncogenic Pathway and Reduces Survival in Imatinib-Resistant Chronic Myelogenous Leukemia Cells.
Patricia Martín-Rodríguez, Borja Guerra, Idaira Hueso-Falcón, Haidee Aranda-Tavío, Juan Díaz-Chico, Angel Amesty

Front Pharmacol· January 2019

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Semisynthesis and Inhibitory Effects of Solidagenone Derivatives on TLR-Mediated Inflammatory Responses.
Irene Cuadrado, Ángel Amesty, Juan Carlos Cedrón, Juan Carlos Oberti, Ana Estévez-Braun

Molecules· December 2018

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