Publications by authors named "Angel Messeguer"

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Structure-Activity Studies of Novel Di-substituted [1,2,5]oxadiazolo [3,4-b]pyrazine Analogs Targeting the A-loop Regulatory Site of p38 MAP Kinase.
Esther Carrasco, Patricia Gomez-Gutierrez, Pedro M Campos, Miguel Vega, Angel Messeguer

Curr Med Chem· May 2022

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Discovery of novel 2,3,5-trisubstituted pyridine analogs as potent inhibitors of IL-1β via modulation of the p38 MAPK signaling pathway.
Esther Carrasco, Patricia Gomez-Gutierrez, Pedro M Campos, Miguel Vega, Angel Messeguer

Eur J Med Chem· November 2021

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Semaphorin 3A-Glycosaminoglycans Interaction as Therapeutic Target for Axonal Regeneration.
Yolanda Pérez, Roman Bonet, Miriam Corredor, Cecilia Domingo, Alejandra Moure, Àngel Messeguer

Pharmaceuticals (Basel)· September 2021

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Inhibition of Sema-3A Promotes Cell Migration, Axonal Growth, and Retinal Ganglion Cell Survival.
Anat Nitzan, Miriam Corredor-Sanchez, Ronit Galron, Limor Nahary, Mary Safrin, Angel Messeguer

Transl Vis Sci Technol· August 2021

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Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6.
F Javier Pérez-Areales, María Garrido, Ester Aso, Manuela Bartolini, Angela De Simone, Angel Messeguer

J Med Chem· September 2020

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Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation.
Pablo Villoslada, Gemma Vila, Valeria Colafrancesco, Beatriz Moreno, Begoña Fernandez-Diez, Joaquin Messeguer, Angel Messeguer

Neurotherapeutics· July 2019

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Dynamic Covalent Identification of an Efficient Heparin Ligand.
Miriam Corredor, Daniel Carbajo, Cecilia Domingo, Yolanda Pérez, Jordi Bujons, Angel Messeguer

Angew Chem Int Ed Engl· September 2018

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First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases.
Aldo Borroto, Diana Reyes-Garau, M Angeles Jiménez, Esther Carrasco, Beatriz Moreno, Angel Messeguer

Sci Transl Med· December 2016

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Synthesis and in vitro, ex-vivo and in vivo activity of hybrid compounds linking a potent ROS and RNS scavenger activity with diverse substrates addressed to pass across the blood-brain barrier.
Laura Vázquez-Jiménez, Maria Garrido, Martina Miceli, Eva Prats, Antonio Ferrer-Montiel, Angel Messeguer

Eur J Med Chem· November 2016

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Regioselective Synthesis of a Family of β-Lactams Bearing a Triazole Moiety as Potential Apoptosis Inhibitors.
Maria Garrido, Miriam Corredor, Mar Orzáez, Ignacio Alfonso, Angel Messeguer

ChemistryOpen· October 2016

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Cationic Peptides and Peptidomimetics Bind Glycosaminoglycans as Potential Sema3A Pathway Inhibitors.
Miriam Corredor, Roman Bonet, Alejandra Moure, Cecilia Domingo, Jordi Bujons, Àngel Messeguer

Biophys J· March 2016

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Apaf1 inhibition promotes cell recovery from apoptosis.
Anna Gortat, Mónica Sancho, Laura Mondragón, Àngel Messeguer, Enrique Pérez-Payá

Protein Cell· November 2015

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Inhibitory effect of positively charged triazine antagonists of prokineticin receptors on the transient receptor vanilloid type-1 (TRPV1) channel.
Luciano De Petrocellis, Aniello Schiano Moriello, Joon Seok Byun, Joo Mi Sohn, Jae Yeol Lee, Angel Messeguer

Pharmacol Res· September 2015

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Efficient Synthesis of Conformationally Restricted Apoptosis Inhibitors Bearing a Triazole Moiety.
Miriam Corredor, Maria Garrido, Jordi Bujons, Mar Orzáez, Enrique Pérez-Payá, Angel Messeguer

Chemistry· September 2015

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Positional Scanning Synthesis of a Peptoid Library Yields New Inducers of Apoptosis that Target Karyopherins and Tubulin.
Glòria Vendrell-Navarro, Federico Rúa, Jordi Bujons, Andreas Brockmeyer, Petra Janning, Angel Messeguer

Chembiochem· July 2015

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Apaf-1 inhibitors protect from unwanted cell death in in vivo models of kidney ischemia and chemotherapy induced ototoxicity.
Mar Orzáez, Mónica Sancho, Sandra Marchán, Laura Mondragón, Rebeca Montava, Angel Messeguer

PLoS One· June 2015

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Effect of triazine derivatives on neuronal nicotinic receptors.
Ana Vázquez-Romero, Manuel Criado, Angel Messeguer, Miquel Vidal-Mosquera, José Mulet

ACS Chem Neurosci· August 2014

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15N NMR spectroscopic and theoretical GIAO-DFT studies for the unambiguous characterization of disubstituted 1,2,3-triazoles.
Miriam Corredor, Jordi Bujons, Àngel Messeguer, Ignacio Alfonso

Org Biomol Chem· November 2013

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Vestibulotoxic properties of potential metabolites of allylnitrile.
Federico Rúa, Mélodie Buffard, Lara Sedó-Cabezón, Gerard Hernández-Mir, Aurélien de la Torre, Angel Messeguer

Toxicol Sci· September 2013

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A polymeric nanomedicine diminishes inflammatory events in renal tubular cells.
Alvaro C Ucero, Sergio Berzal, Carlos Ocaña-Salceda, Mónica Sancho, Mar Orzáez, Angel Messeguer

PLoS One· August 2013

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BH3-mimetics- and cisplatin-induced cell death proceeds through different pathways depending on the availability of death-related cellular components.
Vicente Andreu-Fernández, Ainhoa Genovés, Angel Messeguer, Mar Orzáez, Mónica Sancho

PLoS One· August 2013

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Optimizing the control of apoptosis by amide/triazole isosteric substitution in a constrained peptoid.
Miriam Corredor, Jordi Bujons, Mar Orzáez, Mónica Sancho, Enrique Pérez-Payá, Angel Messeguer

Eur J Med Chem· May 2013

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Synthesis of enantiomerically pure perhydro-1,4-diazepine-2,5-dione and 1,4-piperazine-2,5-dione derivatives exhibiting potent activity as apoptosis inhibitors.
Alejandra Moure, Mar Orzáez, Mónica Sancho, Angel Messeguer

Bioorg Med Chem Lett· December 2012

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Advances in modulating thermosensory TRP channels.
Antonio Ferrer-Montiel, Asia Fernández-Carvajal, Rosa Planells-Cases, Gregorio Fernández-Ballester, José Manuel González-Ros, Angel Messeguer

Expert Opin Ther Pat· September 2012

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Triazine-based vanilloid 1 receptor open channel blockers: design, synthesis, evaluation, and SAR analysis.
Miquel Vidal-Mosquera, Asia Fernández-Carvajal, Alejandra Moure, Pierluigi Valente, Rosa Planells-Cases, Angel Messeguer

J Med Chem· November 2011

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