Publications by authors named "Angela Pacitto"

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Covalent inactivation of Mycobacterium thermoresistibile inosine-5'-monophosphate dehydrogenase (IMPDH).
Ana Trapero, Angela Pacitto, Daniel Shiu-Hin Chan, Chris Abell, Tom L Blundell

Bioorg Med Chem Lett· January 2020

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Synthesis and Structure-Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH.
Vinayak Singh, Angela Pacitto, Stefano Donini, Davide M Ferraris, Sándor Boros

Eur J Med Chem· July 2019

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Fragment-Based Approach to Targeting Inosine-5'-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis.
Ana Trapero, Angela Pacitto, Vinayak Singh, Mohamad Sabbah, Anthony G Coyne

J Med Chem· April 2018

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Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis.
Yumi Park, Angela Pacitto, Tracy Bayliss, Laura A T Cleghorn, Zhe Wang

ACS Infect Dis· January 2017

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The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis.
Vinayak Singh, Stefano Donini, Angela Pacitto, Claudia Sala, Ruben C Hartkoorn

ACS Infect Dis· January 2017

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Lst4, the yeast Fnip1/2 orthologue, is a DENN-family protein.
Angela Pacitto, David B Ascher, Louise H Wong, Beata K Blaszczyk, Ravi K Nookala

Open Biol· December 2015

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Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer.
Ravi K Nookala, Lars Langemeyer, Angela Pacitto, Bernardo Ochoa-Montaño, Jane C Donaldson

Open Biol· August 2012

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