Publications by authors named "Angela S Fleischhacker"

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Heme and CO metabolism by the canonical human heme oxygenases.
Angela S Fleischhacker, Juan Blume-La-Torre, Kierra Pendill, Keion Dozier, Stephen W Ragsdale

J Inorg Biochem· February 2026

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The Role of the [2Fe-2S] Cluster of Escherichia coli IscR in Responding to Redox-Cycling Agents.
Rajdeep Banerjee, Erin L Mettert, Angela S Fleischhacker, Patricia J Kiley

Mol Microbiol· November 2025

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S-adenosyl-L-methionine is the unexpected methyl donor for the methylation of mercury by the membrane-associated HgcAB complex.
Kaiyuan Zheng, Katherine W Rush, Swapneeta S Date, Alexander Johs, Jerry M Parks, Angela S Fleischhacker

Proc Natl Acad Sci U S A· November 2024

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Heme delivery to heme oxygenase-2 involves glyceraldehyde-3-phosphate dehydrogenase.
Yue Dai, Angela S Fleischhacker, Liu Liu, Sara Fayad, Amanda L Gunawan

Biol Chem· November 2022

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Regulation of protein function and degradation by heme, heme responsive motifs, and CO.
Angela S Fleischhacker, Anindita Sarkar, Liu Liu, Stephen W Ragsdale

Crit Rev Biochem Mol Biol· February 2022

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Heme oxygenase-2 (HO-2) binds and buffers labile ferric heme in human embryonic kidney cells.
David A Hanna, Courtney M Moore, Liu Liu, Xiaojing Yuan, Iramofu M Dominic, Angela S Fleischhacker

J Biol Chem· February 2022

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Heme oxygenase-2 is post-translationally regulated by heme occupancy in the catalytic site.
Liu Liu, Arti B Dumbrepatil, Angela S Fleischhacker, E Neil G Marsh, Stephen W Ragsdale

J Biol Chem· December 2020

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The heme-regulatory motifs of heme oxygenase-2 contribute to the transfer of heme to the catalytic site for degradation.
Angela S Fleischhacker, Amanda L Gunawan, Brent A Kochert, Liu Liu, Thomas E Wales

J Biol Chem· April 2020

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Dynamic and structural differences between heme oxygenase-1 and -2 are due to differences in their C-terminal regions.
Brent A Kochert, Angela S Fleischhacker, Thomas E Wales, Donald F Becker, John R Engen

J Biol Chem· May 2019

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Redox Regulation of Heme Oxygenase-2 and the Transcription Factor, Rev-Erb, Through Heme Regulatory Motifs.
Angela S Fleischhacker, Eric L Carter, Stephen W Ragsdale

Antioxid Redox Signal· December 2018

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An unlikely heme chaperone confirmed at last.
Angela S Fleischhacker, Stephen W Ragsdale

J Biol Chem· September 2018

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Comparison of the Mechanisms of Heme Hydroxylation by Heme Oxygenases-1 and -2: Kinetic and Cryoreduction Studies.
Roman Davydov, Angela S Fleischhacker, Ireena Bagai, Brian M Hoffman, Stephen W Ragsdale

Biochemistry· January 2016

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Spectroscopic studies reveal that the heme regulatory motifs of heme oxygenase-2 are dynamically disordered and exhibit redox-dependent interaction with heme.
Ireena Bagai, Ritimukta Sarangi, Angela S Fleischhacker, Ajay Sharma, Brian M Hoffman

Biochemistry· May 2015

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The C-terminal heme regulatory motifs of heme oxygenase-2 are redox-regulated heme binding sites.
Angela S Fleischhacker, Ajay Sharma, Michelle Choi, Andrea M Spencer, Ireena Bagai

Biochemistry· May 2015

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Regulation of iron-sulphur cluster homeostasis through transcriptional control of the Isc pathway by [2Fe-2S]-IscR in Escherichia coli.
Jennifer L Giel, April D Nesbit, Erin L Mettert, Angela S Fleischhacker, Brendan T Wanta

Mol Microbiol· February 2013

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Characterization of the [2Fe-2S] cluster of Escherichia coli transcription factor IscR.
Angela S Fleischhacker, Audria Stubna, Kuang-Lung Hsueh, Yisong Guo, Sarah J Teter

Biochemistry· June 2012

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Does activation of the anti proton, rather than concertedness, determine the stereochemistry of base-catalyzed 1,2-elimination reactions? Anti stereospecificity in E1cB eliminations of β-3-trifluoromethylphenoxy esters, thioesters, and ketones.
Jerry R Mohrig, Brandon G Beyer, Angela S Fleischhacker, Alex J Ruthenburg, Seth G John

J Org Chem· March 2012

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Iron-containing transcription factors and their roles as sensors.
Angela S Fleischhacker, Patricia J Kiley

Curr Opin Chem Biol· April 2011

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Spectroscopic and computational characterization of the base-off forms of cob(II)alamin.
Matthew D Liptak, Angela S Fleischhacker, Rowena G Matthews, Joshua Telser, Thomas C Brunold

J Phys Chem B· April 2009

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Ligand trans influence governs conformation in cobalamin-dependent methionine synthase.
Angela S Fleischhacker, Rowena G Matthews

Biochemistry· October 2007

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Probing the role of the histidine 759 ligand in cobalamin-dependent methionine synthase.
Matthew D Liptak, Angela S Fleischhacker, Rowena G Matthews, Thomas C Brunold

Biochemistry· July 2007

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Conversion of aquifex aeolicus 3-deoxy-d-manno-octulosonate 8-phosphate synthase, a metalloenzyme, into a nonmetalloenzyme.
Jingjing Li, Jing Wu, Angela S Fleischhacker, Ronald W Woodard

J Am Chem Soc· June 2004

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