Publications by authors named "Angela Thornton"

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Eos plays a critical role in Treg homeostasis and modulates the function of recirculating thymic Tregs in the control of Treg development.
Xuan Xie, Angela M Thornton, Shalini Tanwar, Patricia Korty, Alexandria C Wells

Cell Rep· December 2025

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Helios represses megakaryocyte priming in hematopoietic stem and progenitor cells.
Giovanni Cova, Chiara Taroni, Marie-Céline Deau, Qi Cai, Vincent Mittelheisser, Angela M Thornton

J Exp Med· October 2021

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Corrigendum to "Selective deletion of Eos (Ikzf4) in T-regulatory cells leads to loss of suppressive function and development of systemic autoimmunity" [J. Autoimmun. 105C (2019) 102300].
Ameya S Gokhale, Arunakumar Gangaplara, Maria Lopez-Occasio, Angela M Thornton, Ethan M Shevach

J Autoimmun· November 2020

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Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3 Regulatory T Cells.
Yujian H Yang, Roman Istomine, Fernando Alvarez, Tho-Alfakar Al-Aubodah, Xiang Qun Shi, Angela M Thornton

Cell Rep· February 2020

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Selective deletion of Eos (Ikzf4) in T-regulatory cells leads to loss of suppressive function and development of systemic autoimmunity.
Ameya S Gokhale, Arunakumar Gangaplara, Maria Lopez-Occasio, Angela M Thornton, Ethan M Shevach

J Autoimmun· December 2019

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Helios: still behind the clouds.
Angela M Thornton, Ethan M Shevach

Immunology· November 2019

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Helios Deficiency Predisposes the Differentiation of CD4Foxp3 T Cells into Peripherally Derived Regulatory T Cells.
Mathias Skadow, Vinay R Penna, Jessica Galant-Swafford, Ethan M Shevach, Angela M Thornton

J Immunol· July 2019

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Helios and Helios Treg subpopulations are phenotypically and functionally distinct and express dissimilar TCR repertoires.
Angela M Thornton, Jinghua Lu, Patricia E Korty, Yong Chan Kim, Craig Martens

Eur J Immunol· March 2019

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IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation.
Sun-Mi Park, Hyunwoo Cho, Angela M Thornton, Trevor S Barlowe, Timothy Chou

Cell Stem Cell· January 2019

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Overview and Preparation Guide for Academic Careers in Pediatric Pharmacy, Part 1: Career as a Pediatric Pharmacy Practice Faculty Member.
Anita Siu, Allison B Blackmer, Angela M Thornton, Peter N Johnson, Kristen R Nichols

J Pediatr Pharmacol Ther· January 2019

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Academic Careers in Pediatric Pharmacy: Part 2-Academic Advancement.
Allison B Blackmer, Anita Siu, Angela Thornton, Peter N Johnson, Kristen R Nichols

J Pediatr Pharmacol Ther· January 2019

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Tregs, Helios and tumor immunity: the sun has not yet risen.
Angela M Thornton, Ethan M Shevach

Transl Cancer Res· October 2016

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NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.
Chi Ma, Aparna H Kesarwala, Tobias Eggert, José Medina-Echeverz, David E Kleiner, Angela M Thornton

Nature· March 2016

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Helios Controls a Limited Subset of Regulatory T Cell Functions.
Mathew Sebastian, Maria Lopez-Ocasio, Amina Metidji, Sadiye Amcaoglu Rieder, Ethan M Shevach, Angela M Thornton

J Immunol· January 2016

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Eos Is Redundant for Regulatory T Cell Function but Plays an Important Role in IL-2 and Th17 Production by CD4+ Conventional T Cells.
Sadiye Amcaoglu Rieder, Amina Metidji, Deborah Dacek Glass, Angela M Thornton, Tohru Ikeda

J Immunol· July 2015

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Release of active TGF-β1 from the latent TGF-β1/GARP complex on T regulatory cells is mediated by integrin β8.
Justin P Edwards, Angela M Thornton, Ethan M Shevach

J Immunol· September 2014

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tTregs, pTregs, and iTregs: similarities and differences.
Ethan M Shevach, Angela M Thornton

Immunol Rev· May 2014

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Modulation of Treg cells/T effector function by GITR signaling is context-dependent.
Amal Ephrem, Alan L Epstein, Geoffrey L Stephens, Angela M Thornton, Deborah Glass

Eur J Immunol· September 2013

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Oligodeoxynucleotides stabilize Helios-expressing Foxp3+ human T regulatory cells during in vitro expansion.
Yong Chan Kim, Ravikiran Bhairavabhotla, Jeongheon Yoon, Amit Golding, Angela M Thornton

Blood· March 2012

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The deubiquitinase CYLD targets Smad7 protein to regulate transforming growth factor β (TGF-β) signaling and the development of regulatory T cells.
Yongge Zhao, Angela M Thornton, Matthew C Kinney, Chi A Ma, Jacob J Spinner

J Biol Chem· November 2011

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A self-reactive TCR drives the development of Foxp3+ regulatory T cells that prevent autoimmune disease.
Justin R Killebrew, Nikole Perdue, Alan Kwan, Angela M Thornton, Ethan M Shevach

J Immunol· July 2011

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Store-operated Ca(2+) entry (SOCE) contributes to normal skeletal muscle contractility in young but not in aged skeletal muscle.
Angela M Thornton, Xiaoli Zhao, Noah Weisleder, Leticia S Brotto, Sylvain Bougoin

Aging (Albany NY)· June 2011

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Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells.
Angela M Thornton, Patricia E Korty, Dat Q Tran, Elizabeth A Wohlfert, Patrick E Murray

J Immunol· April 2010

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CD4+CD25+ T regulatory cells limit effector T cells and favor the progression of brucellosis in BALB/c mice.
Paolo Pasquali, Angela M Thornton, Silvia Vendetti, Claudia Pistoia, Paola Petrucci

Microbes Infect· January 2010

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Combating Non-nucleoside Reverse Transcriptase Inhibitor Resistance with a Focus On Etravirine (Intelence) for HIV-1 Infection.
Nathaniel Eraikhuemen, Angela M Thornton, Evans Branch, Sandrine T Huynh, Candace Farley

P T· August 2008

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