Publications by authors named "Anna Bonomini"

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Antiviral strategies against influenza virus: an update on approved and innovative therapeutic approaches.
Anna Bonomini, Beatrice Mercorelli, Arianna Loregian

Cell Mol Life Sci· February 2025

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Elaborate Structural Modifications Yielding Novel Boron-Containing N-Substituted Oseltamivir Derivatives as Potent Neuraminidase Inhibitors with Significantly Improved Broad-Spectrum Antiresistance Profiles.
Jiwei Zhang, Ruifang Jia, Huinan Jia, Ping Li, Yuanmin Jiang, Anna Bonomini

J Med Chem· December 2024

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Optimization of potent, broad-spectrum, and specific anti-influenza compounds targeting RNA polymerase PA-PB1 heterodimerization.
Anna Bonomini, Tommaso Felicetti, Martina Pacetti, Chiara Bertagnin, Alice Coletti

Eur J Med Chem· November 2024

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Synergistic activity of an RNA polymerase PA-PB1 interaction inhibitor with oseltamivir against human and avian influenza viruses in cell culture and in ovo.
Anna Bonomini, Jiwei Zhang, Han Ju, Alessia Zago, Martina Pacetti

Antiviral Res· October 2024

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Exploring a New Generation of Pyrimidine and Pyridine Derivatives as Anti-Influenza Agents Targeting the Polymerase PA-PB1 Subunits Interaction.
Ilaria Giacchello, Annarita Cianciusi, Chiara Bertagnin, Anna Bonomini, Valeria Francesconi

Pharmaceutics· July 2024

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Switching the three-component Biginelli-like reaction conditions for the regioselective synthesis of new 2-amino[1,2,4]triazolo[1,5-]pyrimidines.
Martina Pacetti, Maria Chiara Pismataro, Tommaso Felicetti, Federica Giammarino, Anna Bonomini

Org Biomol Chem· January 2024

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A novel -heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation.
Jiwei Zhang, Chuanfeng Liu, Ruifang Jia, Xujie Zhang, Jian Zhang, Anna Bonomini

J Enzyme Inhib Med Chem· December 2023

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Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties.
Ruifang Jia, Jiwei Zhang, Fangyuan Shi, Anna Bonomini, Camilla Lucca

Eur J Med Chem· April 2023

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Iterative Optimization and Structure-Activity Relationship Studies of Oseltamivir Amino Derivatives as Potent and Selective Neuraminidase Inhibitors Targeting 150-Cavity.
Han Ju, Lingxin Hou, Fabao Zhao, Ying Zhang, Ruifang Jia, Anna Bonomini

J Med Chem· September 2022

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Discovery of Novel Boron-Containing -Substituted Oseltamivir Derivatives as Anti-Influenza A Virus Agents for Overcoming N1-H274Y Oseltamivir-Resistant.
Ruifang Jia, Jiwei Zhang, Jian Zhang, Chiara Bertagnin, Anna Bonomini

Molecules· September 2022

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1,2,4-Triazolo[1,5-a]pyrimidines: Efficient one-step synthesis and functionalization as influenza polymerase PA-PB1 interaction disruptors.
Maria Chiara Pismataro, Tommaso Felicetti, Chiara Bertagnin, Maria Giulia Nizi, Anna Bonomini

Eur J Med Chem· October 2021

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