Publications by authors named "Anna Cappa"

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Structure-based design of potent and selective inhibitors of the HECT ligase NEDD4.
Elena Maspero, Anna Cappa, Janine Weber, Paolo Trifirò, Raffaella Amici

Commun Chem· May 2025

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Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models.
Alessia Romussi, Anna Cappa, Paola Vianello, Silvia Brambillasca, Maria Rosaria Cera

ACS Med Chem Lett· May 2020

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Tranylcypromine-Based LSD1 Inhibitors: Structure-Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation.
Rossella Fioravanti, Annalisa Romanelli, Nicola Mautone, Elisabetta Di Bello, Annarita Rovere, Anna Cappa

ChemMedChem· April 2020

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Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model.
Paolo Trifirò, Anna Cappa, Silvia Brambillasca, Oronza A Botrugno, Maria Rosaria Cera

Future Med Chem· July 2017

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Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.
Luca Sartori, Ciro Mercurio, Federica Amigoni, Anna Cappa, Giovanni Fagá

J Med Chem· March 2017

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Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.
Paola Vianello, Luca Sartori, Federica Amigoni, Anna Cappa, Giovanni Fagá

J Med Chem· March 2017

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Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.
Paola Vianello, Oronza A Botrugno, Anna Cappa, Roberto Dal Zuffo, Paola Dessanti

J Med Chem· February 2016

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Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.
Paola Vianello, Oronza A Botrugno, Anna Cappa, Giuseppe Ciossani, Paola Dessanti

Eur J Med Chem· October 2014

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Cinnamic anilides as new mitochondrial permeability transition pore inhibitors endowed with ischemia-reperfusion injury protective effect in vivo.
Daniele Fancelli, Agnese Abate, Raffaella Amici, Paolo Bernardi, Marco Ballarini, Anna Cappa

J Med Chem· June 2014

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Synthesis and biological evaluation of N-hydroxyphenylacrylamides and N-hydroxypyridin-2-ylacrylamides as novel histone deacetylase inhibitors.
Florian Thaler, Andrea Colombo, Antonello Mai, Raffaella Amici, Chiara Bigogno, Anna Cappa

J Med Chem· January 2010

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Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors.
Francesco Leonetti, Marco Catto, Orazio Nicolotti, Leonardo Pisani, Anna Cappa

Bioorg Med Chem· August 2008

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A Simple Method for the Selective Deprotection of p-Methoxybenzyl Ethers by Cerium(III) Chloride Heptahydrate and Sodium Iodide.
Anna Cappa, Enrico Marcantoni, Elisabetta Torregiani, Giuseppe Bartoli, Maria Cristina Bellucci

J Org Chem· July 1999

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