Publications by authors named "Anna Legowska"

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Time-Reduced N-Methylation: Exploring a Faster Synthesis Technique.
Aleksandra Helbik-Maciejewska, Agata Gitlin-Domagalska, Mladena Glavaš, Natalia Ptaszyńska, Dawid Dębowski

J Org Chem· June 2025

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Application of Lipophilic Prodrug Charge Masking Strategy to Obtain Novel, Potential Oxytocin Prodrugs.
Agata Gitlin-Domagalska, Anna Olejnik, Jarosław Ruczyński, Dominika Starego, Natalia Ptaszyńska

Int J Mol Sci· May 2025

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Lactoferricin B Combined with Antibiotics Exhibits Leukemic Selectivity and Antimicrobial Activity.
Jan Jakub Lica, Katarzyna Gucwa, Mateusz Heldt, Anna Stupak, Natalia Maciejewska

Molecules· February 2024

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Dual-Activity Fluoroquinolone-Transportan 10 Conjugates Offer Alternative Leukemia Therapy during Hematopoietic Cell Transplantation.
Jan Jakub Lica, Mateusz Heldt, Milosz Wieczór, Pawel Chodnicki, Natalia Ptaszyńska

Mol Pharmacol· December 2023

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Synthesis of Novel Arginine Building Blocks with Increased Lipophilicity Compatible with Solid-Phase Peptide Synthesis.
Mladena Glavaš, Agata Gitlin-Domagalska, Natalia Ptaszyńska, Dominika Starego, Sylwia Freza

Molecules· November 2023

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Cyclic Peptidic Furin Inhibitors Developed by Combinatorial Chemistry.
Agata Gitlin-Domagalska, Dawid Dębowski, Aleksandra Maciejewska, Sergey Samsonov, Martyna Maszota-Zieleniak

ACS Med Chem Lett· April 2023

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Vasopressin and Its Analogues: From Natural Hormones to Multitasking Peptides.
Mladena Glavaš, Agata Gitlin-Domagalska, Dawid Dębowski, Natalia Ptaszyńska, Anna Łęgowska

Int J Mol Sci· March 2022

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New Peptide Based Fluconazole Conjugates with Expanded Molecular Targets.
Wioletta Brankiewicz, Joanna Okońska, Katarzyna Serbakowska, Jan Lica, Marek Drab

Pharmaceutics· March 2022

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Can Immobilized Artificial Membrane Chromatography Support the Characterization of Antimicrobial Peptide Origin Derivatives?
Krzesimir Ciura, Natalia Ptaszyńska, Hanna Kapica, Monika Pastewska, Anna Łęgowska

Antibiotics (Basel)· October 2021

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Truncation of Huia versabilis Bowman-Birk inhibitor increases its selectivity, matriptase-1 inhibitory activity and proteolytic stability.
Agata Gitlin-Domagalska, Dawid Dębowski, Katarzyna Gucwa, Dominika Starego, Natalia Ptaszyńska

Biochimie· December 2020

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Correction: Stability of Cu(II) complexes with FomA protein fragments containing two His residues in the peptide chain.
Monika Katarzyna Lesiów, Piotr Pietrzyk, Alina Bieńko, Teresa Kowalik-Jankowska, Anna Łęgowska

Metallomics· December 2020

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Cu(II) complexes with peptides from FomA protein containing -His-Xaa-Yaa-Zaa-His and -His-His-motifs. ROS generation and DNA degradation.
Monika Katarzyna Lesiów, Alina Bieńko, Kamila Sobańska, Teresa Kowalik-Jankowska, Krzysztof Rolka

J Inorg Biochem· November 2020

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Conjugates of Ciprofloxacin and Levofloxacin with Cell-Penetrating Peptide Exhibit Antifungal Activity and Mammalian Cytotoxicity.
Natalia Ptaszyńska, Katarzyna Gucwa, Katarzyna Olkiewicz, Mateusz Heldt, Marcin Serocki

Int J Mol Sci· June 2020

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Antibiotic-Based Conjugates Containing Antimicrobial HLopt2 Peptide: Design, Synthesis, Antimicrobial and Cytotoxic Activities.
Natalia Ptaszyńska, Katarzyna Gucwa, Katarzyna Olkiewicz, Anna Łȩgowska, Joanna Okońska

ACS Chem Biol· October 2019

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Peptide conjugates of lactoferricin analogues and antimicrobials-Design, chemical synthesis, and evaluation of antimicrobial activity and mammalian cytotoxicity.
Natalia Ptaszyńska, Katarzyna Olkiewicz, Joanna Okońska, Katarzyna Gucwa, Anna Łęgowska

Peptides· July 2019

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Copper(II) complexes with Fusobacterium nucleatum adhesin FadA: Coordination pattern, physicochemical properties and reactivity.
Katarzyna Krupa, Monika Lesiów, Kamila Stokowa-Sołtys, Radosław Starosta, Natalia Ptaszyńska

J Inorg Biochem· December 2018

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Matriptase-2: monitoring and inhibiting its proteolytic activity.
Agata Gitlin-Domagalska, Martin Mangold, Dawid Dębowski, Natalia Ptaszyńska, Anna Łęgowska

Future Med Chem· December 2018

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Antimicrobial Activity of Chimera Peptides Composed of Human Neutrophil Peptide 1 (HNP-1) Truncated Analogues and Bovine Lactoferrampin.
Natalia Ptaszyńska, Katarzyna Gucwa, Anna Łęgowska, Dawid Dębowski, Agata Gitlin-Domagalska

Bioconjug Chem· September 2018

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Design and chemical syntheses of potent matriptase-2 inhibitors based on trypsin inhibitor SFTI-1 isolated from sunflower seeds.
Agata Gitlin-Domagalska, Dawid Dębowski, Anna Łęgowska, Marit Stirnberg, Joanna Okońska

Biopolymers· November 2017

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Spliced analogues of trypsin inhibitor SFTI-1 and their application for tracing proteolysis and delivery of cargos inside the cells.
Magdalena Filipowicz, Natalia Ptaszyńska, Katarzyna Olkiewicz, Dawid Dębowski, Kamila Ćwikłowska

Biopolymers· March 2017

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Noncovalent inhibitors of human 20S and 26S proteasome based on trypsin inhibitor SFTI-1.
Dawid Dębowski, Mirosława Cichorek, Marta Lubos, Sławomir Wójcik, Anna Łęgowska

Biopolymers· September 2016

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Convenient preparation of deuterium-labeled analogs of peptides containing N-substituted glycines for a stable isotope dilution LC-MS quantitative analysis.
Remigiusz Bąchor, Dawid Dębowski, Anna Łęgowska, Piotr Stefanowicz, Krzysztof Rolka

J Pept Sci· November 2015

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Investigation of Serine-Proteinase-Catalyzed Peptide Splicing in Analogues of Sunflower Trypsin Inhibitor 1 (SFTI-1).
Natalia Karna, Anna Łęgowska, Stanisław Malicki, Dawid Dębowski, Przemysław Golik

Chembiochem· September 2015

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Inhibitors of Matriptase-2 Based on the Trypsin Inhibitor SFTI-1.
Agata Gitlin, Dawid Dębowski, Natalia Karna, Anna Łęgowska, Marit Stirnberg

Chembiochem· July 2015

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Peptide splicing in a double-sequence analogue of trypsin inhibitor SFTI-1 substituted in the P₁ positions by peptoid monomers.
Natalia Karna, Dawid Dębowski, Anna Łęgowska, Remigiusz Bąchor, Zbigniew Szewczuk

Biopolymers· May 2015

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