Publications by authors named "Anna Minarini"

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Exploration of the Neuromodulatory Properties of Fyn and GSK-3β Kinases Exploiting 7-Azaindole-Based Inhibitors.
Giambattista Marotta, Francesca Massenzio, Jose Ortega, Debora Russo, Ilaria Penna, Anna Minarini

J Med Chem· August 2025

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Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties.
Filippo Basagni, Jose A Ortega, Sine M Bertozzi, Andrea Armirotti, Maria Summa, Anna Minarini

Eur J Med Chem· December 2023

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Double Attack to Oxidative Stress in Neurodegenerative Disorders: MAO-B and Nrf2 as Elected Targets.
Filippo Basagni, Maria Luisa Di Paolo, Giorgio Cozza, Lisa Dalla Via, Francesca Fagiani, Anna Minarini

Molecules· November 2023

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From Monoamine Oxidase Inhibition to Antiproliferative Activity: New Biological Perspectives for Polyamine Analogs.
Giulia Nordio, Francesco Piazzola, Giorgio Cozza, Monica Rossetto, Manuela Cervelli, Anna Minarini

Molecules· August 2023

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Polyamine-Drug Conjugates: Do They Boost Drug Activity?
Filippo Basagni, Giambattista Marotta, Michela Rosini, Anna Minarini

Molecules· June 2023

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Inhibition of β-Amyloid Aggregation in Alzheimer's Disease: The Key Role of (Pro)electrophilic Warheads.
Filippo Basagni, Marina Naldi, Tiziana Ginex, F Javier Luque, Francesca Fagiani, Anna Minarini

ACS Med Chem Lett· November 2022

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Role of Fyn Kinase Inhibitors in Switching Neuroinflammatory Pathways.
Giambattista Marotta, Filippo Basagni, Michela Rosini, Anna Minarini

Curr Med Chem· August 2022

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Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies.
Rino Ragno, Anna Minarini, Eleonora Proia, Antonini Lorenzo, Andrea Milelli

J Chem Inf Model· August 2022

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Novel, Potent, and Druglike Tetrahydroquinazoline Inhibitor That Is Highly Selective for Human Topoisomerase II α over β.
Jose Antonio Ortega, Jose M Arencibia, Elirosa Minniti, Jo Ann W Byl, Sebastian Franco-Ulloa, Anna Minarini

J Med Chem· November 2020

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Memantine Derivatives as Multitarget Agents in Alzheimer's Disease.
Giambattista Marotta, Filippo Basagni, Michela Rosini, Anna Minarini

Molecules· September 2020

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Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase.
Maria Luisa Di Paolo, Manuela Cervelli, Paolo Mariottini, Alessia Leonetti, Fabio Polticelli, Anna Minarini

J Enzyme Inhib Med Chem· December 2019

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Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach.
Maria Luisa Di Paolo, Giorgio Cozza, Andrea Milelli, Francesca Zonta, Stefania Sarno, Anna Minarini

FEBS J· December 2019

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Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease.
Michela Rosini, Elena Simoni, Roberta Caporaso, Filippo Basagni, Michele Catanzaro, Anna Minarini

Eur J Med Chem· October 2019

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Distinct biological responses of metastatic castration resistant prostate cancer cells upon exposure to G-quadruplex interacting naphthalenediimide derivatives.
Marta Recagni, Maria Laura Greco, Andrea Milelli, Anna Minarini, Nadia Zaffaroni

Eur J Med Chem· September 2019

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Lights and shadows of electrophile signaling: focus on the Nrf2-Keap1 pathway.
Filippo Basagni, Cristina Lanni, Anna Minarini, Michela Rosini

Future Med Chem· April 2019

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Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ.
Alexandria A Oviatt, Jissy A Kuriappan, Elirosa Minniti, Kendra R Vann, Princess Onuorah, Anna Minarini

Bioorg Med Chem Lett· September 2018

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Novel polyamine-based Histone deacetylases-Lysine demethylase 1 dual binding inhibitors.
Andrea Milelli, Chiara Marchetti, Eleonora Turrini, Elena Catanzaro, Roberta Mazzone, Anna Minarini

Bioorg Med Chem Lett· April 2018

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Pharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity.
Jose Antonio Ortega, Laura Riccardi, Elirosa Minniti, Marco Borgogno, Jose M Arencibia, Anna Minarini

J Med Chem· February 2018

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Novel Polyamine-Naphthalene Diimide Conjugates Targeting Histone Deacetylases and DNA for Cancer Phenotype Reprogramming.
Alice Pasini, Chiara Marchetti, Claudia Sissi, Marilisa Cortesi, Emanuele Giordano, Anna Minarini

ACS Med Chem Lett· December 2017

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Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα.
Elirosa Minniti, Jo Ann W Byl, Laura Riccardi, Claudia Sissi, Michela Rosini, Anna Minarini

Bioorg Med Chem Lett· October 2017

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Quinazoline based α-adrenoreceptor antagonists with potent antiproliferative activity in human prostate cancer cell lines.
Valentina Maestri, Andrea Tarozzi, Elena Simoni, Antonio Cilia, Elena Poggesi, Anna Minarini

Eur J Med Chem· August 2017

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Targeting the Nrf2/Amyloid-Beta Liaison in Alzheimer's Disease: A Rational Approach.
Elena Simoni, Melania M Serafini, Roberta Caporaso, Chiara Marchetti, Marco Racchi, Anna Minarini

ACS Chem Neurosci· July 2017

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Multitarget drug design strategy in Alzheimer's disease: focus on cholinergic transmission and amyloid-β aggregation.
Elena Simoni, Manuela Bartolini, Izuddin F Abu, Alix Blockley, Cecilia Gotti, Anna Minarini

Future Med Chem· June 2017

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Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains.
Andrea Milelli, Chiara Marchetti, Maria Laura Greco, Federica Moraca, Giosuè Costa, Anna Minarini

Eur J Med Chem· March 2017

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Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer's Disease.
Elena Simoni, Roberta Caporaso, Christian Bergamini, Jessica Fiori, Romana Fato, Anna Minarini

ACS Med Chem Lett· December 2016

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