Publications by authors named "Anna Paruzynski"

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Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial.
Juanita Lopez, Thomas Powles, Fadi Braiteh, Lillian L Siu, Patricia LoRusso, Anna Paruzynski

Nat Med· January 2025

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The balance between the intronic miR-342 and its host gene Evl determines hematopoietic cell fate decision.
Friederike Herbst, Tonio J L Lang, Elias S P Eckert, Peer Wünsche, Alexander A Wurm, Anna Paruzynski

Leukemia· October 2021

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Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs.
Peer Wünsche, Elias S P Eckert, Tim Holland-Letz, Anna Paruzynski, Agnes Hotz-Wagenblatt

Cell Stem Cell· July 2018

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Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer.
Ugur Sahin, Evelyna Derhovanessian, Matthias Miller, Björn-Philipp Kloke, Petra Simon, Anna Paruzynski

Nature· July 2017

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Successful Combination of Sequential Gene Therapy and Rescue Allo-HSCT in Two Children with X-CGD - Importance of Timing.
Ulrich Siler, Anna Paruzynski, Heidi Holtgreve-Grez, Elena Kuzmenko, Ulrike Koehl

Curr Gene Ther· June 2016

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Gene therapy for Wiskott-Aldrich Syndrome-Long-term reconstitution and clinical benefits, but increased risk for leukemogenesis.
Christian Joerg Braun, Maximilian Witzel, Anna Paruzynski, Kaan Boztug, Christof von Kalle

Rare Dis· March 2016

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High-resolution analysis of the human T-cell receptor repertoire.
Eliana Ruggiero, Jan P Nicolay, Raffaele Fronza, Anne Arens, Anna Paruzynski

Nat Commun· September 2015

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High-throughput monitoring of integration site clonality in preclinical and clinical gene therapy studies.
Frank A Giordano, Jens-Uwe Appelt, Barbara Link, Sebastian Gerdes, Christina Lehrer, Anna Paruzynski

Mol Ther Methods Clin Dev· June 2015

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Cell cycle status of CD34(+) hemopoietic stem cells determines lentiviral integration in actively transcribed and development-related genes.
Eleni Papanikolaou, Anna Paruzynski, Ioannis Kasampalidis, Annette Deichmann, Evangelos Stamateris

Mol Ther· April 2015

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Gene therapy for Wiskott-Aldrich syndrome--long-term efficacy and genotoxicity.
Christian Jörg Braun, Kaan Boztug, Anna Paruzynski, Maximilian Witzel, Adrian Schwarzer

Sci Transl Med· March 2014

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Targeted resequencing for analysis of clonal composition of recurrent gene mutations in chronic lymphocytic leukaemia.
Alexander Jethwa, Jennifer Hüllein, Tatjana Stolz, Carolin Blume, Leopold Sellner, Anna Paruzynski

Br J Haematol· November 2013

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Next-generation sequencing of cancer consensus genes in lymphoma.
Jennifer Hüllein, Alexander Jethwa, Tatjana Stolz, Carolin Blume, Leopold Sellner, Anna Paruzynski

Leuk Lymphoma· August 2013

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The fetal mouse is a sensitive genotoxicity model that exposes lentiviral-associated mutagenesis resulting in liver oncogenesis.
Ali Nowrouzi, Wing T Cheung, Tingting Li, Xuegong Zhang, Anne Arens, Anna Paruzynski

Mol Ther· February 2013

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Analysis of the clonal repertoire of gene-corrected cells in gene therapy.
Anna Paruzynski, Hanno Glimm, Manfred Schmidt, Christof von Kalle

Methods Enzymol· June 2012

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Bioinformatic clonality analysis of next-generation sequencing-derived viral vector integration sites.
Anne Arens, Jens-Uwe Appelt, Cynthia C Bartholomae, Richard Gabriel, Anna Paruzynski

Hum Gene Ther Methods· April 2012

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Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy.
Annette Deichmann, Martijn H Brugman, Cynthia C Bartholomae, Kerstin Schwarzwaelder, Monique M A Verstegen, Anna Paruzynski

Mol Ther· November 2011

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Retroviral gene therapy for X-linked chronic granulomatous disease: results from phase I/II trial.
Hyoung Jin Kang, Cynthia C Bartholomae, Anna Paruzynski, Anne Arens, Sujeong Kim

Mol Ther· November 2011

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Lentiviral vector integration profiles differ in rodent postmitotic tissues.
Cynthia C Bartholomae, Anne Arens, Kamaljit S Balaggan, Rafael J Yáñez-Muñoz, Eugenio Montini, Anna Paruzynski

Mol Ther· April 2011

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Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing.
Anna Paruzynski, Anne Arens, Richard Gabriel, Cynthia C Bartholomae, Simone Scholz

Nat Protoc· August 2010

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Comprehensive genomic access to vector integration in clinical gene therapy.
Richard Gabriel, Ralph Eckenberg, Anna Paruzynski, Cynthia C Bartholomae, Ali Nowrouzi

Nat Med· December 2009

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