Publications by authors named "Anna Plotka"

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Talazoparib Formulation Bridging in Cancer Patients-Challenges and the Critical Role of Model-Informed Drug Development in Approval Despite Failed Bioequivalence.
Diane Wang, Cathy Cen Guo, Xizhe Gao, Yibo Wang, Yanke Yu, Anna Plotka

CPT Pharmacometrics Syst Pharmacol· December 2025

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Advancing Early Clinical Trials: The Transformative Potential of Decentralized Designs and Digital Technologies in Phase 1 Clinical Trial.
Bimal K Malhotra, Josué Kunjom Mfopou, Isabelle Huyghe, Pascal Ryckmans, Nathalie Severs, Anna Plotka

Clin Pharmacol Ther· November 2025

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Drug-drug interaction profile of ritlecitinib as perpetrator and victim through cytochrome P450.
Vivek S Purohit, Yeamin Huh, Martin E Dowty, Anna Plotka, Alexandre Lejeune

Br J Clin Pharmacol· August 2025

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A Phase 1, Open-Label Study of the Pharmacokinetics of Ritlecitinib in Children Aged 6-12 Years With Alopecia Areata.
Mercedes E Gonzalez, John Browning, Stacy Smith, Anna Plotka, Jing Daisy Zhu

Pediatr Dermatol· July 2025

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The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Ritlecitinib, a Janus Kinase 3 and Tyrosine-Protein Kinase Family Inhibitor, in Humans.
Jonathan N Bauman, Angela C Doran, Gabrielle M Gualtieri, Brian Hee, Timothy Strelevitz, Anna Plotka

Drug Metab Dispos· September 2024

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Utilization of Rosuvastatin and Endogenous Biomarkers in Evaluating the Impact of Ritlecitinib on BCRP, OATP1B1, and OAT3 Transporter Activity.
Yeamin Huh, Anna Plotka, Hua Wei, Julia Kaplan, Nancy Raha

Pharm Res· November 2023

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Evaluation of the Impact of Ritlecitinib on Organic Cation Transporters Using Sumatriptan and Biomarkers as Probes.
Xiaoxing Wang, Vivek Purohit, Martin E Dowty, David Rodrigues, Lina Luo, Anna Plotka

J Clin Pharmacol· July 2023

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Evaluation of the effect of ritlecitinib on the pharmacokinetics of caffeine in healthy participants.
Jian Liu, Rohit Solan, Robert Wolk, Anna Plotka, Melissa T O'Gorman

Br J Clin Pharmacol· July 2023

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BCR::ABL1-like acute lymphoblastic leukaemia: a single institution experience on identification of potentially therapeutic targetable cases.
Anna Płotka, Anna Przybyłowicz-Chalecka, Maria Korolczuk, Zuzanna Kanduła, Błażej Ratajczak

Mol Cytogenet· July 2023

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Leveraging Prior Healthy Participant Pharmacokinetic Data to Evaluate the Impact of Renal and Hepatic Impairment on Ritlecitinib Pharmacokinetics.
Vivek Purohit, Yeamin Huh, Jessica Wojciechowski, Anna Plotka, Stephanie Salts

AAPS J· March 2023

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Comparison of diagnostic and treatment processes among pediatric and adolescents and young adults' populations suffering from acute lymphoblastic leukemia and lymphomas.
Gazala Abdulaziz-Opiela, Anna Sobieraj, Anna Płotka, Barbara Więckowska, Lidia Gil

Front Oncol· February 2023

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HRAS mutation positive multiple myeloma in the type 2 CALR mutation positive essential thrombocythemia: A case report.
Krzysztof Lewandowski, Agata Kopydłowska, Zuzanna Kanduła, Bartłomiej Sankowski, Marcin Machnicki

J Cell Mol Med· January 2023

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Evaluation of pharmacokinetics and safety of talazoparib in patients with advanced cancer and varying degrees of hepatic impairment.
Cen Guo, Yanke Yu, Jayeta Chakrabarti, Sarina A Piha-Paul, Rebecca Moroose, Anna Plotka

Br J Clin Pharmacol· July 2022

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BCR/ABL1-Like Acute Lymphoblastic Leukemia: From Diagnostic Approaches to Molecularly Targeted Therapy.
Anna Płotka, Krzysztof Lewandowski

Acta Haematol· April 2022

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Psychosocial Late Effects in Adolescent and Young Adult Survivors of Childhood Cancer Diagnosed with Leukemia, Lymphoma, and Central Nervous System Tumor.
Anna Płotka, Aleksandra Chęcińska, Olga Zając-Spychała, Barbara Więckowska, Lucyna Kramer

J Adolesc Young Adult Oncol· August 2021

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The Effect of Renal Impairment on the Pharmacokinetics and Safety of Talazoparib in Patients with Advanced Solid Tumors.
Chandrasekar Durairaj, Jayeta Chakrabarti, Cristiano Ferrario, Holger W Hirte, Sunil Babu, Anna Plotka

Clin Pharmacokinet· July 2021

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Palbociclib (PD-0332991) pharmacokinetics in subjects with impaired renal function.
Yanke Yu, Justin Hoffman, Anna Plotka, Melissa O'Gorman, Haihong Shi

Cancer Chemother Pharmacol· December 2020

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Effect of Renal or Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intravenous Rivipansel.
Brinda K Tammara, Kelly Ryan, Anna Plotka, Frank E Shafer, Hua Wei

Clin Pharmacol Drug Dev· November 2020

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Evaluation of the effect of P-glycoprotein inhibition and induction on talazoparib disposition in patients with advanced solid tumours.
Mohamed Elmeliegy, István Láng, Elena A Smolyarchuk, Chin-Hee Chung, Anna Plotka

Br J Clin Pharmacol· April 2020

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A Phase 1 Mass Balance Study of C-Labeled Talazoparib in Patients With Advanced Solid Tumors.
Yanke Yu, Chin-Hee Chung, Anna Plotka, Kevin Quinn, Haihong Shi

J Clin Pharmacol· September 2019

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Talazoparib has no clinically relevant effect on QTc interval in patients with advanced solid tumors.
Justin Hoffman, Jayeta Chakrabarti, Anna Plotka, Adriana Milillo Naraine, David Kanamori

Anticancer Drugs· June 2019

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Successful Management of a Child With Drug-induced Necrotizing Pancreatitis During Acute Lymphoblastic Leukemia Therapy: A Case Report.
Anna Płotka, Agnieszka Wziątek, Jacek Wachowiak, Katarzyna Derwich

J Pediatr Hematol Oncol· March 2019

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Comparative Pharmacokinetics and Pharmacodynamics of Bococizumab Following a Single Subcutaneous Injection Using Drug Substance Manufactured at Two Sites or Administration via Two Different Devices.
Ellen Q Wang, Anna Plotka, Joanne Salageanu, Daniel Baltrukonis, Khurshid Mridha

Clin Pharmacol Drug Dev· January 2019

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Pharmacokinetics, pharmacodynamics, and safety of bococizumab, a monoclonal antibody against proprotein convertase subtilisin/kexin type 9, in healthy subjects when administered in co-mixture with recombinant human hyaluronidase: A phase 1 randomized trial.
Almasa Bass, Anna Plotka, Khurshid Mridha, Catherine Sattler, Albert M Kim

Health Sci Rep· September 2018

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Assessment of Relative Bioavailability of Moroctocog Alfa and Moroctocog Alfa (AF-CC) in Subjects With Severe Hemophilia A.
Joan Korth-Bradley, Jeremy Rupon, Anna Plotka, Robert Charnigo, Pablo Rendo

Clin Transl Sci· May 2018

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