Publications by authors named "Anna R McCarthy"

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Correction: Modulation of p53 C-Terminal Acetylation by Mdm2, p14ARF, and Cytoplasmic SirT2.
Ingeborg M M van Leeuwen, Maureen Higgins, Johanna Campbell, Anna R McCarthy, Marijke C C Sachweh

Mol Cancer Ther· December 2023

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Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Marcus J G W Ladds, Ingeborg M M van Leeuwen, Catherine J Drummond, Su Chu, Alan R Healy, Anna R McCarthy

Nat Commun· August 2023

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Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenib.
Marcus J G W Ladds, Andrés Pastor-Fernández, Gergana Popova, Ingeborg M M van Leeuwen, Kai Er Eng, Anna R McCarthy

PLoS One· July 2018

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Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Marcus J G W Ladds, Ingeborg M M van Leeuwen, Catherine J Drummond, Su Chu, Alan R Healy, Anna R McCarthy

Nat Commun· May 2018

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A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Marcus J G W Ladds, Ingeborg M M van Leeuwen, Catherine J Drummond, Su Chu, Alan R Healy, Anna R McCarthy

Nat Commun· March 2018

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Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells.
Marijke C C Sachweh, William C Stafford, Catherine J Drummond, Anna R McCarthy, Maureen Higgins

Oncotarget· June 2015

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Acetylation site specificities of lysine deacetylase inhibitors in human cells.
Christian Schölz, Brian T Weinert, Sebastian A Wagner, Petra Beli, Yasuyuki Miyake, Anna R McCarthy

Nat Biotechnol· April 2015

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Tenovin-D3, a novel small-molecule inhibitor of sirtuin SirT2, increases p21 (CDKN1A) expression in a p53-independent manner.
Anna R McCarthy, Marijke C C Sachweh, Maureen Higgins, Johanna Campbell, Catherine J Drummond

Mol Cancer Ther· April 2013

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Modulation of p53 C-terminal acetylation by mdm2, p14ARF, and cytoplasmic SirT2.
Ingeborg M M van Leeuwen, Maureen Higgins, Johanna Campbell, Anna R McCarthy, Marijke C C Sachweh

Mol Cancer Ther· April 2013

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Discovery and validation of SIRT2 inhibitors based on tenovin-6: use of a ¹H-NMR method to assess deacetylase activity.
Lisa Pirrie, Anna R McCarthy, Louise L Major, Vaida Morkūnaitė, Asta Zubrienė

Molecules· October 2012

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Synthesis and biological characterisation of sirtuin inhibitors based on the tenovins.
Anna R McCarthy, Lisa Pirrie, Jonathan J Hollick, Sebastien Ronseaux, Johanna Campbell

Bioorg Med Chem· March 2012

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Mechanism-specific signatures for small-molecule p53 activators.
Ingeborg M M van Leeuwen, Maureen Higgins, Johanna Campbell, Christopher J Brown, Anna R McCarthy

Cell Cycle· May 2011

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The discovery of nongenotoxic activators of p53: building on a cell-based high-throughput screen.
Anna R McCarthy, Jonathan J Hollick, Nicholas J Westwood

Semin Cancer Biol· February 2010

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Novel cambinol analogs as sirtuin inhibitors: synthesis, biological evaluation, and rationalization of activity.
Federico Medda, Rupert J M Russell, Maureen Higgins, Anna R McCarthy, Johanna Campbell

J Med Chem· May 2009

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Characterization, chemical optimization and anti-tumour activity of a tubulin poison identified by a p53-based phenotypic screen.
Oliver D Staples, Jonathan J Hollick, Johanna Campbell, Maureen Higgins, Anna R McCarthy

Cell Cycle· November 2008

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Evaluation of 4'-substituted bicyclic pyridones as non-steroidal inhibitors of steroid 5alpha-reductase.
Anna R McCarthy, Rolf W Hartmann, Andrew D Abell

Bioorg Med Chem Lett· July 2007

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Estrogenicity of pyrethroid insecticide metabolites.
Anna R McCarthy, Barbara M Thomson, Ian C Shaw, Andrew D Abell

J Environ Monit· January 2006

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