Publications by authors named "Anna Rowland"

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Cryo-EM structure of the human THIK-1 K2P K channel reveals a lower Y gate regulated by lipids and anesthetics.
Karin E J Rödström, Bisher Eymsh, Peter Proks, Mehtab S Hayre, Sönke Cordeiro, Anna Rowland

Nat Struct Mol Biol· July 2025

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Discovery of CVN293, a Brain Permeable KCNK13 (THIK-1) Inhibitor Suitable for Clinical Assessment.
Roland W Bürli, Kevin J Doyle, Louise Dickson, Anna Rowland, Kim Matthews

ACS Med Chem Lett· May 2024

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Protocol for kinetic mode potassium channel assays on common plate readers and microscopes.
Emery Smith, Louise Dickson, Philip Pickford, Anna Rowland, Justin Shumate

SLAS Discov· April 2024

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Discovery and first-time disclosure of CVN766, an exquisitely selective orexin 1 receptor antagonist.
Angela Glen, Roland W Bürli, David Livermore, William Buffham, Stephanie Merison, Anna E Rowland

Bioorg Med Chem Lett· March 2024

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Differential contribution of THIK-1 K channels and P2X7 receptors to ATP-mediated neuroinflammation by human microglia.
Ali Rifat, Bernardino Ossola, Roland W Bürli, Lee A Dawson, Nicola L Brice, Anna Rowland

J Neuroinflammation· February 2024

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Discovery of , a Novel Brain-Penetrant α6-Containing Nicotinic Receptor Antagonist for the Modulation of Motor Dysfunction.
Louisa A Christie, Nicola L Brice, Anna Rowland, Louise Dickson, Rishi Anand

J Med Chem· September 2023

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Characterisation of C101248: A novel selective THIK-1 channel inhibitor for the modulation of microglial NLRP3-inflammasome.
Bernardino Ossola, Ali Rifat, Anna Rowland, Helen Hunter, Samuel Drinkall

Neuropharmacology· February 2023

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Balancing Public Protection with Fairness to Doctors.
Anna Rowland

Med Leg J· June 2018

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GMC review of fitness to practise procedures is complete.
Anna Rowland

BMJ· July 2016

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