Publications by authors named "Anne Debant"

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De novo and inherited monoallelic variants in TUBA4A cause ataxia and spasticity.
Mehdi Benkirane, Marion Bonhomme, Heba Morsy, Stephanie L Safgren, Cecilia Marelli, Anne Debant

Brain· November 2024

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An Anti-Invasive Role for Mdmx through the RhoA GTPase under the Control of the NEDD8 Pathway.
Lara J Bou Malhab, Susanne Schmidt, Christine Fagotto-Kaufmann, Emmanuelle Pion, Gilles Gadea, Anne Debant

Cells· September 2024

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Extending the phenotypes associated with TRIO gene variants in a cohort of 25 patients and review of the literature.
Gabriella Gazdagh, David Hunt, Anna Maria Cueto Gonzalez, Monserrat Pons Rodriguez, Ayeshah Chaudhry, Anne Debant

Am J Med Genet A· July 2023

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Pathogenic TRIO variants associated with neurodevelopmental disorders perturb the molecular regulation of TRIO and axon pathfinding in vivo.
Maxime Bonnet, Fiona Roche, Christine Fagotto-Kaufmann, Gabriella Gazdagh, Iona Truong, Anne Debant

Mol Psychiatry· April 2023

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The +TIP Navigator-1 is an actin-microtubule crosslinker that regulates axonal growth cone motility.
Carlos Sánchez-Huertas, Marion Bonhomme, Amandine Falco, Christine Fagotto-Kaufmann, Jeffrey van Haren, Anne Debant

J Cell Biol· September 2020

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Opposite Modulation of RAC1 by Mutations in TRIO Is Associated with Distinct, Domain-Specific Neurodevelopmental Disorders.
Sónia Barbosa, Stephanie Greville-Heygate, Maxime Bonnet, Annie Godwin, Christine Fagotto-Kaufmann, Anne Debant

Am J Hum Genet· March 2020

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Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination.
Maria I Acosta, Serge Urbach, Anne Doye, Yuen-Wai Ng, Jérôme Boudeau, Anne Debant

Sci Rep· January 2018

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Recurrent TRIO Fusion in Nontranslocation-Related Sarcomas.
Lucile Delespaul, Tom Lesluyes, Gaëlle Pérot, Céline Brulard, Lydia Lartigue, Anne Debant

Clin Cancer Res· February 2017

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Mutations specific to the Rac-GEF domain of cause intellectual disability and microcephaly.
Reuben J Pengelly, Stephanie Greville-Heygate, Susanne Schmidt, Eleanor G Seaby, M Reza Jabalameli, Anne Debant

J Med Genet· November 2016

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Comprehensive prognostic analysis in breast cancer integrating clinical, tumoral, micro-environmental and immunohistochemical criteria.
Isabelle de Mascarel, Marc Debled, Véronique Brouste, Louis Mauriac, Ghislaine Sierankowski, Anne Debant

Springerplus· September 2015

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Hsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1.
Jonathan DeGeer, Andrew Kaplan, Pierre Mattar, Morgane Morabito, Ursula Stochaj, Anne Debant

J Cell Biol· August 2015

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The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.
Fanny Jaudon, Fabrice Raynaud, Rosine Wehrlé, Jean-Michel Bellanger, Mohamed Doulazmi, Anne Debant

Mol Biol Cell· June 2015

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Function and regulation of the Rho guanine nucleotide exchange factor Trio.
Susanne Schmidt, Anne Debant

Small GTPases· February 2015

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Identification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesis.
Aude Cannet, Susanne Schmidt, Bénédicte Delaval, Anne Debant

Mol Biol Cell· December 2014

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Aptamer-derived peptide inhibitors of Rho guanine nucleotide exchange factors.
Susanne Schmidt, Anne Debant

Enzymes· August 2014

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Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.
Jeffrey van Haren, Jérôme Boudeau, Susanne Schmidt, Sreya Basu, Zhe Liu, Anne Debant

Curr Biol· August 2014

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Random mutagenesis of peptide aptamers as an optimization strategy for inhibitor screening.
Nathalie Bouquier, Sylvie Fromont, Anne Debant, Susanne Schmidt

Methods Mol Biol· February 2013

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Tyrosine phosphorylation of the Rho guanine nucleotide exchange factor Trio regulates netrin-1/DCC-mediated cortical axon outgrowth.
Jonathan DeGeer, Jérôme Boudeau, Susanne Schmidt, Fiona Bedford, Nathalie Lamarche-Vane, Anne Debant

Mol Cell Biol· February 2013

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A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors.
Jose P Vaqué, Robert T Dorsam, Xiaodong Feng, Ramiro Iglesias-Bartolome, David J Forsthoefel, Anne Debant

Mol Cell· January 2013

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The doublecortin-related gene zyg-8 is a microtubule organizer in Caenorhabditis elegans neurons.
Jean-Michel Bellanger, Juan G Cueva, Renee Baran, Garland Tang, Miriam B Goodman, Anne Debant

J Cell Sci· November 2012

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A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invagination.
Timothy F Plageman, Bharesh K Chauhan, Christine Yang, Fanny Jaudon, Xun Shang, Anne Debant

Development· December 2011

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Kidins220/ARMS regulates Rac1-dependent neurite outgrowth by direct interaction with the RhoGEF Trio.
Veronika E Neubrand, Claire Thomas, Susanne Schmidt, Anne Debant, Giampietro Schiavo

J Cell Sci· June 2010

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Aptamer-derived peptides as potent inhibitors of the oncogenic RhoGEF Tgat.
Nathalie Bouquier, Sylvie Fromont, Jean-Christophe Zeeh, Camille Auziol, Pauline Larrousse, Anne Debant

Chem Biol· April 2009

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Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.
Anne Briançon-Marjollet, Atefeh Ghogha, Homaira Nawabi, Ibtissem Triki, Camille Auziol, Anne Debant

Mol Cell Biol· April 2008

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Trio controls the mature organization of neuronal clusters in the hindbrain.
Stéphanie Backer, Matías Hidalgo-Sánchez, Nicolas Offner, Elodie Portales-Casamar, Anne Debant

J Neurosci· September 2007

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