Publications by authors named "Annette Affolter"

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Irradiation‑induced cellular senescence is linked to pro‑survival signaling and checkpoint regulation in a 2D and 3D model for head and neck cancer.
Luis Bugia, Annette Affolter, Johann Kern, Emma Sohn, Frederic Jungbauer

Oncol Rep· November 2025

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Real-World Outcomes of Immune Checkpoint Inhibitors in Head and Neck Squamous Cell Carcinoma: Analyzing Patient-Specific Factors Influencing Survival and Response Rate.
Lena Huber, Constanze Kohler, Anne Lammert, Claudia Scherl, Sonja Ludwig, Annette Affolter

Cancer Rep (Hoboken)· November 2025

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Preventing Free Flap Complications: Key Factors to Keep in Mind.
Jonas Kornmann, Rasmus Schug, Lena Huber, Anne Lammert, Frederic Jungbauer, Annette Affolter

J Surg Oncol· October 2025

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Xeno-free alternatives to the use of fetal bovine serum in head and neck cancer explant culture.
Alexya Azhakesan, Elena Seiz, Johann Kern, Laura Hendricks, Jens Fleckenstein, Annette Affolter

Altern Lab Anim· July 2025

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3D Bioprinted Head and Neck Squamous Cell Carcinoma (HNSCC) Model Using Tunicate Derived Nanocellulose (NC) Bioink.
Alexya Azhakesan, Johann Kern, Ankit Mishra, Christine Selhuber-Unkel, Annette Affolter

Adv Healthc Mater· March 2025

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Nivolumab as a Promising Treatment Option for Metastatic Salivary Duct Carcinoma.
Luis Bugia, Frederic Jungbauer, Lena Zaubitzer, Christian Hörner, Kirsten Merx, Annette Affolter

J Immunother· September 2024

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C-Reactive Protein Kinetic as a Potential Predictive and Prognostic Factor during Treatment with Checkpoint Inhibitors in R/M-HNSCC.
Frederic Jungbauer, Claudia Scherl, Nicole Rotter, Annette Affolter, Anne Lammert

Cancers (Basel)· June 2024

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Risk factors for immune-related adverse effects during CPI therapy in patients with head and neck malignancies - a single center study.
Frederic Jungbauer, Annette Affolter, Christoph Brochhausen, Anne Lammert, Sonja Ludwig

Front Oncol· February 2024

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Point Cloud Registration for Measuring Shape Dependence of Soft Tissue Deformation by Digital Twins in Head and Neck Surgery.
Sara Monji-Azad, David Männle, Jürgen Hesser, Jan Pohlmann, Nicole Rotter, Annette Affolter

Biomed Hub· January 2024

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Modulation of PD‑L1 expression by standard therapy in head and neck cancer cell lines and exosomes.
Annette Affolter, Kai Liebel, Luisa Tengler, Elena Seiz, Moritz Tiedtke

Int J Oncol· September 2023

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Artificial intelligence directed development of a digital twin to measure soft tissue shift during head and neck surgery.
David Männle, Jan Pohlmann, Sara Monji-Azad, Jürgen Hesser, Nicole Rotter, Annette Affolter

PLoS One· August 2023

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Climate change adaptation and mitigation measures for alluvial aquifers - Solution approaches based on the thermal exploitation of managed aquifer (MAR) and surface water recharge (MSWR).
Epting Jannis, Love Råman Vinnå, Affolter Annette, Scheidler Stefan, Oliver S Schilling

Water Res· June 2023

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Plasma-derived small extracellular vesicles unleash the angiogenic potential in head and neck cancer patients.
Luisa Tengler, Julia Schütz, Moritz Tiedtke, Jadwiga Jablonska, Marie-Nicole Theodoraki, Annette Affolter

Mol Med· May 2023

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Augmented reality during parotid surgery: real-life evaluation of voice control of a head mounted display.
Claudia Scherl, David Männle, Nicole Rotter, Jürgen Hesser, Jan Stallkamp, Annette Affolter

Eur Arch Otorhinolaryngol· April 2023

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Optimisation of Conditions for the Formation of Spheroids of Head and Neck Squamous Cell Carcinoma Cell Lines for Use as Animal Alternatives.
Esther Tenschert, Johann Kern, Annette Affolter, Nicole Rotter, Anne Lammert

Altern Lab Anim· November 2022

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Conjoint analysis of OPRPN and SMR3A protein expression as potential predictive biomarkers for head and neck squamous cell carcinoma after radiotherapy.
Chao Rong, Jennifer Grünow, Julia Thierauf, Carlota Lucena-Porcel, Gerald Major, Annette Affolter

Oncol Rep· September 2022

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Biomarkers and 3D models predicting response to immune checkpoint blockade in head and neck cancer (Review).
Annette Affolter, Johann Kern, Karen Bieback, Claudia Scherl, Nicole Rotter

Int J Oncol· July 2022

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[Time management in operating rooms-a cross-sectional study to evaluate estimated and objective durations of otorhinolaryngologic surgical procedures].
Lena Zaubitzer, Annette Affolter, Sylvia Büttner, Sonja Ludwig, Nicole Rotter

HNO· June 2022

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3D cell culture alters signal transduction and drug response in head and neck squamous cell carcinoma.
Jonas Heid, Annette Affolter, Yvonne Jakob, Johann Kern, Nicole Rotter

Oncol Lett· June 2022

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Augmented reality with HoloLens in parotid surgery: how to assess and to improve accuracy.
Claudia Scherl, Johanna Stratemeier, Celine Karle, Nicole Rotter, Jürgen Hesser, Annette Affolter

Eur Arch Otorhinolaryngol· July 2021

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Precision Medicine Gains Momentum: Novel 3D Models and Stem Cell-Based Approaches in Head and Neck Cancer.
Annette Affolter, Anne Lammert, Johann Kern, Claudia Scherl, Nicole Rotter

Front Cell Dev Biol· July 2021

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[The tumor stem cell niche of head and neck - point of intersection with therapeutic potential?].
Anne Lammert, Annette Affolter, David Gvaramia, Jonas Heid, Frederic Jungbauer

Laryngorhinootologie· January 2021

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Organotypic Co-Cultures as a Novel 3D Model for Head and Neck Squamous Cell Carcinoma.
Luca Engelmann, Julia Thierauf, Natalia Koerich Laureano, Hans-Juergen Stark, Elena-Sophie Prigge, Annette Affolter

Cancers (Basel)· August 2020

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Adaptive ERK signalling activation in response to therapy and in silico prognostic evaluation of EGFR-MAPK in HNSCC.
Chao Rong, Marie F Muller, Fang Xiang, Alexandra Jensen, Wilko Weichert, Annette Affolter

Br J Cancer· July 2020

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Validating the Xerostomia Inventory in a radiation-induced xerostomia population in German language.
Ralph Hohenberger, Ingo Baumann, Peter K Plinkert, Regina Brinster, Johannes Krisam, Annette Affolter

Oral Dis· October 2019

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