Publications by authors named "Annette Beck-Sickinger"

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Dual Targeting Approach Using 4-Hydroxytamoxifen Neuropeptide Y Conjugates for Selective Addressing of Adipose Tissue.
Anna Kohler, Eva-Maria Jülke, Luke C Darveniza, Jan Stichel, Annette G Beck-Sickinger

ChemMedChem· December 2025

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Receptor-Mediated Shuttling of a D-Amino Acid Peptide Achieves High Nanomolar Cytosolic Concentrations.
Moritz List, Annette G Beck-Sickinger

J Am Chem Soc· December 2025

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The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors.
Stephen P H Alexander, Anthony P Davenport, Eamonn Kelly, Alasdair J Gibb, Alistair A Mathie, Annette G Beck-Sickinger

Br J Pharmacol· December 2025

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Structural insights into the binding modes of Arrestin-3 finger loop to the neuropeptide Y and Y receptors.
Varsha Gupta, Jeannette M Laugwitz, Mateusz Sklodowski, Matthias Voitel, Davide Sala, Annette G Beck-Sickinger

Structure· October 2025

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Transient ligand contacts of the intrinsically disordered N-terminus of neuropeptide Y receptor regulate arrestin-3 recruitment.
Anette Kaiser, Juan C Rojas Echeverri, Asat Baischew, Maik Pankonin, Karl D Leitner, Annette G Beck-Sickinger

Nat Commun· September 2025

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MRAP2 modifies the signaling and oligomerization state of the melanocortin-4 receptor.
Iqra Sohail, Suli-Anne Laurin, Gunnar Kleinau, Vidicha Chunilal, Andrew Morton, Annette G Beck-Sickinger

Nat Commun· September 2025

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Bio-inspired biomaterial coating for enzyme responsive release of antimicrobial peptides.
Dennis A Böhner, Karin Mörl, Annette G Beck-Sickinger

Mater Today Bio· August 2025

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Development of Mutant M Muscarinic Receptors Biased for G Protein Activation or Recruitment of β-Arrestins.
Jaroslawna Meister, Lizzy Wanka, Nicole A Perry-Hauser, Liu Liu, Tina M Iverson, Annette G Beck-Sickinger

Biochemistry· July 2025

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Peptide therapeutics: current status and future opportunity with focus on nose-to-brain delivery☆.
Eva-Maria Jülke, Annette G Beck-Sickinger

Peptides· June 2025

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Similar Binding Mode of a 5-Sulfonylthiouracil Derivative Antagonist at Chemerin Receptors CMKLR1 and GPR1.
Tina Schermeng, Alexander Fürll, Fabian Liessmann, Lukas von Bredow, Jan Stichel, Annette G Beck-Sickinger

J Med Chem· June 2025

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Intranasal Application of Peptides Modulating the Neuropeptide Y System.
Eva-Maria Jülke, Benginur Özbay, Marcin Nowicki, Sylvia Els-Heindl, Kerstin Immig, Annette G Beck-Sickinger

ACS Pharmacol Transl Sci· April 2025

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Hederagenin is a Highly Selective Antagonist of the Neuropeptide FF Receptor 1 that Reveals Mechanisms for Subtype Selectivity.
Hannah Lentschat, Fabian Liessmann, Claiborne Tydings, Tina Schermeng, Jan Stichel, Annette G Beck-Sickinger

Angew Chem Int Ed Engl· February 2025

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Binding Mode of Cyclic Chemerin-9 Peptide and ChemerinS157 Protein at CMKLR1.
Tina Schermeng, Fabian Liessmann, Carla Katharina Ambrosius, Jens Meiler, Annette G Beck-Sickinger

Chembiochem· January 2025

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Design and Biofunctionalization of Cloud Sponge-Inspired Scaffolds for Enhanced Bone Cell Performance.
Philipp Zimmermann, Peter Schulze, Annette G Beck-Sickinger, Yuliya Khrunyk

ACS Appl Bio Mater· December 2024

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Comparison of Protocols to Test Peptide Stability in Blood Plasma and Cell Culture Supernatants.
Anna Kohler, Eva-Maria Jülke, Jan Stichel, Annette G Beck-Sickinger

ACS Pharmacol Transl Sci· November 2024

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Targeted modulation of gene expression through receptor-specific delivery of small interfering RNA peptide conjugates.
Mareike Schenk, Karin Mörl, Stephan Herzig, Annette G Beck-Sickinger

J Pept Sci· October 2024

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Development of a Potent and Selective G2A (GPR132) Agonist.
Victor Hernandez-Olmos, Jan Heering, Beatrice Marinescu, Tina Schermeng, Vladimir V Ivanov, Annette G Beck-Sickinger

J Med Chem· July 2024

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Melanocortin-4 Receptor PLC Activation Is Modulated by an Interaction with the Monocarboxylate Transporter 8.
Larissa Anthofer, Philipp Gmach, Zeynep Cansu Uretmen Kagiali, Gunnar Kleinau, Jonas Rotter, Annette G Beck-Sickinger

Int J Mol Sci· July 2024

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An orally available Ca2.2 calcium channel inhibitor for the treatment of neuropathic pain.
Janine Kutzsche, Gustavo A Guzman, Antje Willuweit, Olaf Kletke, Esther Wollert, Annette G Beck-Sickinger

Br J Pharmacol· June 2024

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Illuminating the neuropeptide Y receptor and its ligand pancreatic polypeptide from a structural, functional, and therapeutic perspective.
Corinna Schüß, Victoria Behr, Annette G Beck-Sickinger

Neuropeptides· June 2024

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LRP1 is the cell-surface endocytosis receptor for vaspin in adipocytes.
Catherine A Tindall, Kevin Möhlis, Inka Rapöhn, Sebastian Dommel, Veronika Riedl, Annette G Beck-Sickinger

FEBS J· May 2024

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Illuminating the Path to Enhanced Bioimaging by Phosphole-based Fluorophores.
Mareike Schenk, Nils König, Evamarie Hey-Hawkins, Annette G Beck-Sickinger

Chembiochem· March 2024

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Structural basis of G protein-Coupled receptor CMKLR1 activation and signaling induced by a chemerin-derived agonist.
Xuan Zhang, Tina Weiß, Mary Hongying Cheng, Siqi Chen, Carla Katharina Ambrosius, Annette G Beck-Sickinger

PLoS Biol· December 2023

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Development of Radiopharmaceuticals for NPY Receptor-5 (Y5) Nuclear Imaging in Tumors by Synthesis of Specific Agonists and Investigation of Their Binding Mode.
Sacha Bodin, Lisa C Peuker, Emmanuelle Jestin, Isabel D Alves, Valérie Velasco, Annette G Beck-Sickinger

Bioconjug Chem· November 2023

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The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors.
Stephen P H Alexander, Arthur Christopoulos, Anthony P Davenport, Eamonn Kelly, Alistair A Mathie, Annette G Beck-Sickinger

Br J Pharmacol· October 2023

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