Publications by authors named "Annie Clark"

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Phase II INTEGRIS-PSC trial of bexotegrast, an αβ/αβ integrin inhibitor, in primary sclerosing cholangitis.
Gideon M Hirschfield, Kris V Kowdley, Palak J Trivedi, Bertus Eksteen, Bilal Hameed, Annie Clark

J Hepatol· January 2026

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Dual αβ and αβ Inhibition over 12 Weeks Reduces Active Type I Collagen Deposition in Individuals with Idiopathic Pulmonary Fibrosis: A Phase 2, Double-Blind, Placebo-controlled Clinical Trial.
Sydney B Montesi, Gregory P Cosgrove, Scott M Turner, Iris Y Zhou, Nikos Efthimiou, Annie Clark

Am J Respir Crit Care Med· July 2025

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Bexotegrast Shows Dose-Dependent Integrin αβ Receptor Occupancy in Lungs of Participants with Idiopathic Pulmonary Fibrosis: A Phase 2, Open-Label Clinical Trial.
Joshua J Mooney, Susan Jacobs, Éric A Lefebvre, Gregory P Cosgrove, Annie Clark

Ann Am Thorac Soc· March 2025

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Bexotegrast in people with idiopathic pulmonary fibrosis (IPF): a plain language summary of publication of the INTEGRIS-IPF study.
Lisa Lancaster, Vincent Cottin, Murali Ramaswamy, Wim A Wuyts, R Gisli Jenkins, Annie Clark

Ther Adv Respir Dis· November 2024

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Bexotegrast in Patients with Idiopathic Pulmonary Fibrosis: The INTEGRIS-IPF Clinical Trial.
Lisa Lancaster, Vincent Cottin, Murali Ramaswamy, Wim A Wuyts, R Gisli Jenkins, Annie Clark

Am J Respir Crit Care Med· August 2024

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CSF Proteomics in Patients With Progressive Supranuclear Palsy.
Amy Wise, Jingyao Li, Mai Yamakawa, Joseph Loureiro, Brant Peterson, Annie Clark

Neurology· August 2024

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Examining Associations Between Smartphone Use and Clinical Severity in Frontotemporal Dementia: Proof-of-Concept Study.
Emily W Paolillo, Kaitlin B Casaletto, Annie L Clark, Jack C Taylor, Hilary W Heuer

JMIR Aging· June 2024

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Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration.
Adam M Staffaroni, Annie L Clark, Jack C Taylor, Hilary W Heuer, Mark Sanderson-Cimino, David Clark

JAMA Netw Open· April 2024

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Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research.
Jack Carson Taylor, Hilary W Heuer, Annie L Clark, Amy B Wise, Masood Manoochehri

Alzheimers Dement (Amst)· May 2023

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Temporal order of clinical and biomarker changes in familial frontotemporal dementia.
Adam M Staffaroni, Melanie Quintana, Barbara Wendelberger, Hilary W Heuer, Lucy L Russell, Annie L Clark

Nat Med· October 2022

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Young mice administered adult doses of AAV5-hFVIII-SQ achieve therapeutic factor VIII expression into adulthood.
Lening Zhang, Bridget Yates, Ryan Murphy, Su Liu, Lin Xie, Annie Clark

Mol Ther Methods Clin Dev· September 2022

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Ultra-sensitive AAV capsid detection by immunocapture-based qPCR following factor VIII gene transfer.
Krystal Sandza, Annie Clark, Elli Koziol, Hassibullah Akeefe, Fan Yang

Gene Ther· February 2022

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Design, Formulation, and Evaluation of Novel Dissolving Microarray Patches Containing Rilpivirine for Intravaginal Delivery.
Maelíosa T C Mc Crudden, Eneko Larrañeta, Annie Clark, Courtney Jarrahian, Annie Rein-Weston

Adv Healthc Mater· May 2019

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Design, formulation and evaluation of novel dissolving microarray patches containing a long-acting rilpivirine nanosuspension.
Maelíosa T C Mc Crudden, Eneko Larrañeta, Annie Clark, Courtney Jarrahian, Annie Rein-Weston

J Control Release· December 2018

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The application of half-life in clinical decision making: Comparison of the pharmacokinetics of extended-release topiramate (USL255) and immediate-release topiramate.
Barry E Gidal, Annie M Clark, Bob Anders, Frank Gilliam

Epilepsy Res· January 2017

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Pharmacokinetic-Pharmacodynamic Modeling of Intravenous and Oral Topiramate and Its Effect on the Symbol-Digit Modalities Test in Adult Healthy Volunteers.
Chay Ngee Lim, Angela K Birnbaum, Richard C Brundage, Ilo E Leppik, James C Cloyd, Annie Clark

J Clin Pharmacol· June 2016

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Long-term safety and sustained efficacy of USL255 (topiramate extended-release capsules) in patients with refractory partial-onset seizures.
Steve S Chung, R Edward Hogan, Ilan Blatt, Balduin Lawson P, Huy Nguyen, Annie M Clark

Epilepsy Behav· June 2016

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Clinical utility of topiramate extended-release capsules (USL255): Bioequivalence of USL255 sprinkled and intact capsule in healthy adults and an in vitro evaluation of sprinkle delivery via enteral feeding tubes.
Annie M Clark, John M Pellock, Mary Holmay, Bob Anders, James Cloyd

Epilepsy Behav· April 2016

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Pharmacokinetic-pharmacodynamic modelling of intravenous and oral topiramate and its effect on phonemic fluency in adult healthy volunteers.
Ghada F Ahmed, Susan E Marino, Richard C Brundage, Serguei V S Pakhomov, Ilo E Leppik, Annie Clark

Br J Clin Pharmacol· May 2015

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Efficacy of once-daily extended-release topiramate (USL255): a subgroup analysis based on the level of treatment resistance.
R Edward Hogan, Ilan Blatt, Balduin Lawson, Venkatesh Nagaraddi, Toufic A Fakhoury, Annie M Clark

Epilepsy Behav· December 2014

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USL255 extended-release topiramate: dose-proportional pharmacokinetics and tolerability in healthy volunteers.
Annie M Clark, Mark B Halvorsen, Tricia L Braun, Krista M Johnson, James C Cloyd

Epilepsia· July 2014

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Once-daily USL255 as adjunctive treatment of partial-onset seizures: randomized phase III study.
Steve S Chung, Toufic A Fakhoury, R Edward Hogan, Venkatesh N Nagaraddi, Ilan Blatt, Annie M Clark

Epilepsia· July 2014

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Plasma topiramate concentrations resulting from doses associated with neuroprotection against white matter injury and stroke in two strains of rat pups.
Annie M Clark, John T Mondick, James C Cloyd, Athena F Zuppa, Yogendra H Raol

Pediatr Res· March 2013

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Use of the vacuum extractor by midwives--what has changed in the last decade?
P Annie Clark

J Midwifery Womens Health· August 2006

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