Publications by authors named "Anthony Addlagatta"

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Quantitative estimation of squalene levels in acute respiratory distress syndrome (ARDS) and treated lung tissues by gas chromatography-mass spectrometry.
Bala Manikantha Adimoolam, Aruna Jangam, S Babu Dadinaboyina, Sai Balaji Andugulapati, Anthony Addlagatta

Anal Methods· August 2025

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Development of acylhydrazone linked thiazoles as non-covalent dual inhibitors of SARS-CoV-2 proteases.
Vidya Jyothi Alli, Shubham Kumar Singh, Mounika Darna, Vavilapalli Suresh, Swapnil Anil Sule, Anthony Addlagatta

Eur J Med Chem· June 2025

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Strategic enzymatic enantioselective desymmetrization of prochiral cyclohexa-2,5-dienones.
Bhavita Kattula, Anandarao Munakala, Rajnandani Kashyap, Tarun Nallamilli, Narendra Kumar Nagendla, Anthony Addlagatta

Chem Commun (Camb)· June 2024

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Development of 2-chloroquinoline based heterocyclic frameworks as dual inhibitors of SARS-CoV-2 M and PL.
Bhavita Kattula, Bharati Reddi, Aruna Jangam, Lekhika Naik, Bala Manikanta Adimoolam, Anthony Addlagatta

Int J Biol Macromol· July 2023

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Genomic characterization and evolutionary analysis of dengue virus from mosquitoes in Telangana, India.
Priyanka Sankoju, Venkata Sriram Uday Ravinuthala, Rajasekhar Mopuri, Srinivasa Rao Mutheneni, Anthony Addlagatta

J Vector Borne Dis· July 2023

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Anti-inflammatory and antioxidant activities of Gymnema Sylvestre extract rescue acute respiratory distress syndrome in rats via modulating the NF-κB/MAPK pathway.
Aruna Jangam, Satya Krishna Tirunavalli, Bala Manikantha Adimoolam, Bhavana Kasireddy, Samata Sai Patnaik, Anthony Addlagatta

Inflammopharmacology· April 2023

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A single amino acid difference between archaeal and human type 2 methionine aminopeptidases differentiates their affinity towards ovalicin.
Sandeepchowdary Bala, Bharati Reddi, Anthony Addlagatta

Biochim Biophys Acta Proteins Proteom· February 2023

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Regioselectivity in inhibition of peptide deformylase from Haemophilus influenzae by 4- vs 5-azaindole hydroxamic acid derivatives: Biochemical, structural and antimicrobial studies.
Bharati Reddi, Chandan Kishor, Aruna Jangam, Sandeepchowdary Bala, Uma Rajeswari Batchu, Anthony Addlagatta

Bioorg Chem· November 2022

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Design, Synthesis and Mechanistic Studies of Novel Isatin-Pyrazole Hydrazone Conjugates as Selective and Potent Bacterial MetAP Inhibitors.
Iram Irfan, Asghar Ali, Bharati Reddi, Mohd Abrar Khan, Phool Hasan, Anthony Addlagatta

Antibiotics (Basel)· August 2022

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Selective inhibition of Helicobacter pylori methionine aminopeptidase by azaindole hydroxamic acid derivatives: Design, synthesis, in vitro biochemical and structural studies.
Sandeepchowdary Bala, Kalisha Vali Yellamanda, Anilkumar Kadari, Venkata S U Ravinuthala, Bhavita Kattula, Anthony Addlagatta

Bioorg Chem· October 2021

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Exo-selective intermolecular Diels-Alder reaction by PyrI4 and AbnU on non-natural substrates.
Rajnandani Kashyap, Naga Veera Yerra, Joachyutharayalu Oja, Sandeepchowdary Bala, Gal Reddy Potuganti, Anthony Addlagatta

Commun Chem· August 2021

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Methionine aminopeptidases with short sequence inserts within the catalytic domain are differentially inhibited: Structural and biochemical studies of three proteins from Vibrio spp.
Vijaykumar Pillalamarri, Chilakala Gangi Reddy, Sandeep Chowdary Bala, Aruna Jangam, Vinny Vinod Kutty, Anthony Addlagatta

Eur J Med Chem· January 2021

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Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis.
Ravikumar Reddi, Roopa Jones Ganji, Anil Kumar Marapaka, Sandeep Chowdary Bala, Naga Veera Yerra, Anthony Addlagatta

Int J Biol Macromol· December 2020

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Bengamides display potent activity against drug-resistant Mycobacterium tuberculosis.
Diana H Quan, Gayathri Nagalingam, Ian Luck, Nicholas Proschogo, Vijaykumar Pillalamarri, Anthony Addlagatta

Sci Rep· October 2019

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Unraveling structural insights of ribokinase from Leishmania donovani.
Santhosh Gatreddi, Vijaykumar Pillalamarri, Dileep Vasudevan, Anthony Addlagatta, Insaf Ahmed Qureshi

Int J Biol Macromol· September 2019

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Discovery of a new class of type 1 methionine aminopeptidases that have relaxed substrate specificity.
Sandeep Chowdary Bala, Neshatul Haque, Vijaykumar Pillalamarri, Ravikumar Reddi, Rajnandani Kashyap, Anthony Addlagatta

Int J Biol Macromol· May 2019

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Discovery of natural product ovalicin sensitive type 1 methionine aminopeptidases: molecular and structural basis.
Vijaykumar Pillalamarri, Tarun Arya, Neshatul Haque, Sandeep Chowdary Bala, Anil Kumar Marapaka, Anthony Addlagatta

Biochem J· March 2019

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Synthesis and mechanistic studies of diketo acids and their bioisosteres as potential antibacterial agents.
Phool Hasan, Vijay K Pillalamarri, Babita Aneja, Mohammad Irfan, Mudsser Azam, Anthony Addlagatta

Eur J Med Chem· February 2019

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Discovery, Structural and Biochemical Studies of a rare Glu/Asp Specific M1 Class Aminopeptidase from Legionella pneumophila.
Anil Kumar Marapaka, Vijaykumar Pillalamarri, Rajesh Gumpena, Neshatul Haque, Sandeep Chowdary Bala, Anthony Addlagatta

Int J Biol Macromol· December 2018

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Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases.
Emmanuel Salomon, Marjorie Schmitt, Anil Kumar Marapaka, Athanasios Stamogiannos, Germain Revelant, Anthony Addlagatta

Molecules· October 2018

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Human Naa50 Protein Displays Broad Substrate Specificity for Amino-terminal Acetylation: DETAILED STRUCTURAL AND BIOCHEMICAL ANALYSIS USING TETRAPEPTIDE LIBRARY.
Ravikumar Reddi, Venkateshwarlu Saddanapu, Dinesh Kumar Chinthapalli, Priyanka Sankoju, Prabhakar Sripadi, Anthony Addlagatta

J Biol Chem· September 2016

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Expression, Functional Characterization and X-ray Analysis of HosA, A Member of MarR Family of Transcription Regulator from Uropathogenic Escherichia coli.
Ajit Roy, Ravikumar Reddi, Bhavik Sawhney, Debasish Kumar Ghosh, Anthony Addlagatta

Protein J· August 2016

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The unique functional role of the C-HS hydrogen bond in the substrate specificity and enzyme catalysis of type 1 methionine aminopeptidase.
Ravikumar Reddi, Kiran Kumar Singarapu, Debnath Pal, Anthony Addlagatta

Mol Biosyst· July 2016

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Highly functionalized tetrahydropyridines are cytotoxic and selective inhibitors of human puromycin sensitive aminopeptidase.
Raghunath Aeluri, Roopa Jones Ganji, Anil Kumar Marapaka, Vijaykumar Pillalamarri, Manjula Alla, Anthony Addlagatta

Eur J Med Chem· December 2015

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Chemical shift assignments of zinc finger domain of methionine aminopeptidase 1 (MetAP1) from Homo sapiens.
Kavitha Rachineni, Tarun Arya, Kiran Kumar Singarapu, Anthony Addlagatta, Jagadeesh Bharatam

Biomol NMR Assign· October 2015

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