Publications by authors named "Anthony Brumby"

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Cooperates with Oncogenic in Tumourigenesis via the JNK and PI3K Pathways in epithelial Tissue.
Carole L C Poon, Anthony M Brumby, Helena E Richardson

Int J Mol Sci· May 2018

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BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila.
Karen Doggett, Nezaket Turkel, Lee F Willoughby, Jason Ellul, Michael J Murray, Anthony M Brumby

PLoS One· May 2016

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Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis.
Nezaket Turkel, Marta Portela, Carole Poon, Jason Li, Anthony M Brumby

Biol Open· July 2015

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The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state.
Nezaket Turkel, Virender K Sahota, Jessica E Bolden, Karen R Goulding, Karen Doggett, Anthony M Brumby

PLoS Genet· January 2014

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In Drosophila, RhoGEF2 cooperates with activated Ras in tumorigenesis through a pathway involving Rho1-Rok-Myosin-II and JNK signalling.
Peytee Khoo, Kirsten Allan, Lee Willoughby, Anthony M Brumby, Helena E Richardson

Dis Model Mech· May 2013

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An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery.
Lee F Willoughby, Tanja Schlosser, Samuel A Manning, John P Parisot, Ian P Street, Anthony M Brumby

Dis Model Mech· March 2013

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Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling.
Karen Doggett, Felix A Grusche, Helena E Richardson, Anthony M Brumby

BMC Dev Biol· September 2011

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Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis.
Anthony M Brumby, Karen R Goulding, Tanja Schlosser, Sherene Loi, Ryan Galea

Genetics· May 2011

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Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs.
Gregory R Leong, Karen R Goulding, Nancy Amin, Helena E Richardson, Anthony M Brumby

BMC Biol· September 2009

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Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye.
Nicola A Grzeschik, Nancy Amin, Julie Secombe, Anthony M Brumby, Helena E Richardson

Dev Biol· November 2007

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Using Drosophila melanogaster to map human cancer pathways.
Anthony M Brumby, Helena E Richardson

Nat Rev Cancer· August 2005

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New tricks for old dogs: unexpected roles for cell cycle regulators revealed using animal models.
Patrick O Humbert, Anthony M Brumby, Leonie M Quinn, Helena E Richardson

Curr Opin Cell Biol· December 2004

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A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila.
Anthony Brumby, Julie Secombe, Julie Horsfield, Michelle Coombe, Nancy Amin

Genetics· September 2004

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hScrib is a functional homologue of the Drosophila tumour suppressor Scribble.
Lukas E Dow, Anthony M Brumby, Rosa Muratore, Michelle L Coombe, Karin A Sedelies

Oncogene· December 2003

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scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila.
Anthony M Brumby, Helena E Richardson

EMBO J· November 2003

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Drosophila cyclin E interacts with components of the Brahma complex.
Anthony M Brumby, Claudia B Zraly, Julie A Horsfield, Julie Secombe, Robert Saint

EMBO J· July 2002

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Analysis of Drosophila cyclin EI and II function during development: identification of an inhibitory zone within the morphogenetic furrow of the eye imaginal disc that blocks the function of cyclin EI but not cyclin EII.
Donna Crack, Julie Secombe, Michelle Coombe, Anthony Brumby, Robert Saint

Dev Biol· January 2002

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