Publications by authors named "Anthony Hunt"

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An exploration of knowledge-organizing technologies to advance transdisciplinary back pain research.
Jeffrey C Lotz, Glen Ropella, Paul Anderson, Qian Yang, Michael A Hedderich, C Anthony Hunt

JOR Spine· December 2023

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Theoretical Schemas to Guide Back Pain Consortium (BACPAC) Chronic Low Back Pain Clinical Research.
Anthony Chau, Sharis Steib, Evans Whitaker, David Kohns, Alexander Quinter, C Anthony Hunt

Pain Med· August 2023

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Utilizing virtual experiments to increase understanding of discrepancies involving in vitro-to-in vivo predictions of hepatic clearance.
Preethi Krishnan, Andrew K Smith, Glen E P Ropella, Lopamudra Dutta, Ryan C Kennedy, C Anthony Hunt

PLoS One· July 2022

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Biomedical research models in the science of fracture healing - Pitfalls & promises.
Meir T Marmor, Hannah Dailey, Ralph Marcucio, Anthony C Hunt

Injury· October 2020

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Contrasting model mechanisms of alanine aminotransferase (ALT) release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms.
Andrew K Smith, Glen E P Ropella, Mitchell R McGill, Preethi Krishnan, Lopamudra Dutta, C Anthony Hunt

PLoS Comput Biol· June 2020

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Nocturnal torpor by superb fairy-wrens: a key mechanism for reducing winter daily energy expenditure.
Alex B Romano, Anthony Hunt, Justin A Welbergen, Christopher Turbill

Biol Lett· June 2019

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Propagation of Pericentral Necrosis During Acetaminophen-Induced Liver Injury: Evidence for Early Interhepatocyte Communication and Information Exchange.
Ryan C Kennedy, Andrew K Smith, Glen E P Ropella, Mitchell R McGill, Hartmut Jaeschke, C Anthony Hunt

Toxicol Sci· May 2019

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The Spectrum of Mechanism-Oriented Models and Methods for Explanations of Biological Phenomena.
C Anthony Hunt, Ahmet Erdemir, William W Lytton, Feilim Mac Gabhann, Edward A Sander

Processes (Basel)· May 2018

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A Model Mechanism-Based Explanation of an In Vitro-In Vivo Disconnect for Improving Extrapolation and Translation.
Andrew K Smith, Yanli Xu, Glen E P Ropella, C Anthony Hunt

J Pharmacol Exp Ther· April 2018

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Simulation enabled search for explanatory mechanisms of the fracture healing process.
Ryan C Kennedy, Meir Marmor, Ralph Marcucio, C Anthony Hunt

PLoS Comput Biol· February 2018

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Virtual Experiments Enable Exploring and Challenging Explanatory Mechanisms of Immune-Mediated P450 Down-Regulation.
Brenden K Petersen, Glen E P Ropella, C Anthony Hunt

PLoS One· July 2017

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Competing Mechanistic Hypotheses of Acetaminophen-Induced Hepatotoxicity Challenged by Virtual Experiments.
Andrew K Smith, Brenden K Petersen, Glen E P Ropella, Ryan C Kennedy, Neil Kaplowitz, C Anthony Hunt

PLoS Comput Biol· December 2016

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A cell-centered, agent-based framework that enables flexible environment granularities.
Ryan C Kennedy, Glen Ep Ropella, C Anthony Hunt

Theor Biol Med Model· February 2016

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In silico, experimental, mechanistic model for extended-release felodipine disposition exhibiting complex absorption and a highly variable food interaction.
Sean H J Kim, Andre J Jackson, C Anthony Hunt

PLoS One· June 2015

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Tuneable resolution as a systems biology approach for multi-scale, multi-compartment computational models.
Denise E Kirschner, C Anthony Hunt, Simeone Marino, Mohammad Fallahi-Sichani, Jennifer J Linderman

Wiley Interdiscip Rev Syst Biol Med· February 2015

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Toward modular biological models: defining analog modules based on referent physiological mechanisms.
Brenden K Petersen, Glen E P Ropella, C Anthony Hunt

BMC Syst Biol· August 2014

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Novel wave intensity analysis of arterial pulse wave propagation accounting for peripheral reflections.
Jordi Alastruey, Anthony A E Hunt, Peter D Weinberg

Int J Numer Method Biomed Eng· February 2014

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Agent-based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity.
C Anthony Hunt, Ryan C Kennedy, Sean H J Kim, Glen E P Ropella

Wiley Interdiscip Rev Syst Biol Med· January 2014

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Haemodynamics in the mouse aortic arch computed from MRI-derived velocities at the aortic root.
Mark A Van Doormaal, Asimina Kazakidi, Marzena Wylezinska, Anthony Hunt, Jordi L Tremoleda

J R Soc Interface· November 2012

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Individualized, discrete event, simulations provide insight into inter- and intra-subject variability of extended-release, drug products.
Sean H J Kim, Andre J Jackson, Rim Hur, C Anthony Hunt

Theor Biol Med Model· August 2012

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Enabling clearance predictions to emerge from in silico actions of quasi-autonomous hepatocyte components.
Shahab Sheikh-Bahaei, C Anthony Hunt

Drug Metab Dispos· October 2011

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Relational grounding facilitates development of scientifically useful multiscale models.
C Anthony Hunt, Glen E P Ropella, Tai ning Lam, Andrew D Gewitz

Theor Biol Med Model· September 2011

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MDCK cystogenesis driven by cell stabilization within computational analogues.
Jesse A Engelberg, Anirban Datta, Keith E Mostov, C Anthony Hunt

PLoS Comput Biol· April 2011

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Cloud computing and validation of expandable in silico livers.
Glen E P Ropella, C Anthony Hunt

BMC Syst Biol· December 2010

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Computational experiments reveal plausible mechanisms for changing patterns of hepatic zonation of xenobiotic clearance and hepatotoxicity.
Shahab Sheikh-Bahaei, Jacquelyn J Maher, C Anthony Hunt

J Theor Biol· August 2010

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