Publications by authors named "Anthony Hyman"

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A label-free method for measuring the composition of multicomponent biomolecular condensates.
Patrick M McCall, Kyoohyun Kim, Anna Shevchenko, Martine Ruer-Gruß, Jan Peychl, Anthony A Hyman

Nat Chem· December 2025

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CD-CODE 2.0: an enhanced condensate knowledgebase integrating pathobiology, condensate modulating drugs, and host-pathogen interactions.
Ksenia Kuznetsova, Maxim Scheremetjew, Jialin Yin, HongKee Moon, Diego A Vargas, Anthony A Hyman

Nucleic Acids Res· November 2025

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Computational design of metalloproteases.
Anqi Chen, Kejia Wu, Hojae Choi, Preetham Venkatesh, Samuel J Pellock, Anthony A Hyman

bioRxiv· November 2025

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Small-molecule dissolution of stress granules by redox modulation benefits ALS models.
Hiroyuki Uechi, Sindhuja Sridharan, Jik Nijssen, Jessica Bilstein, Juan M Iglesias-Artola, Anthony A Hyman

Nat Chem Biol· October 2025

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Quantifying collective interactions in biomolecular phase separation.
Hannes Ausserwöger, Ella de Csilléry, Daoyuan Qian, Georg Krainer, Timothy J Welsh, Anthony A Hyman

Nat Commun· August 2025

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Single-step discovery of high-affinity RNA ligands by UltraSelex.
Yaqing Zhang, Yuan Jiang, David Kuster, Qiwei Ye, Wenhao Huang, Anthony A Hyman

Nat Chem Biol· July 2025

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Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates.
Xiao Yan, David Kuster, Priyesh Mohanty, Jik Nijssen, Karina Pombo-García, Anthony A Hyman

Cell· July 2025

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SARS-CoV-2 nucleocapsid protein directly prevents cGAS-DNA recognition through competitive binding.
Theresia Gutmann, David Kuster, Anthony A Hyman

Proc Natl Acad Sci U S A· July 2025

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A mechanism for MEX-5-driven disassembly of PGL-3/RNA condensates in vitro.
Natasha S Lewis, Silja Zedlitz, Hannes Ausserwöger, Patrick M McCall, Lars Hubatsch, Anthony A Hyman

Proc Natl Acad Sci U S A· May 2025

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Functional specificity in biomolecular condensates revealed by genetic complementation.
Benjamin R Sabari, Anthony A Hyman, Denes Hnisz

Nat Rev Genet· April 2025

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Assembly of tight junction belts by ZO1 surface condensation and local actin polymerization.
Daxiao Sun, Xueping Zhao, Tina Wiegand, Cecilie Martin-Lemaitre, Tom Borianne, Anthony A Hyman

Dev Cell· April 2025

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SUMO2/3 conjugation of TDP-43 protects against aggregation.
Enza Maria Verde, Francesco Antoniani, Laura Mediani, Valentina Secco, Samuele Crotti, Anthony A Hyman

Sci Adv· February 2025

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Mesoscale landscaping of the TRIM protein family reveals a novel human condensatopathy.
Hari R Singh, Vineeta Sharma, Jik Nijssen, Andrei Pozniakovski, Alexander Rubin, Anthony A Hyman

bioRxiv· January 2025

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Actin polymerization counteracts prewetting of N-WASP on supported lipid bilayers.
Tina Wiegand, Jinghui Liu, Lutz Vogeley, Isabel LuValle-Burke, Jan Geisler, Anthony A Hyman

Proc Natl Acad Sci U S A· December 2024

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PICNIC accurately predicts condensate-forming proteins regardless of their structural disorder across organisms.
Anna Hadarovich, Hari Raj Singh, Soumyadeep Ghosh, Maxim Scheremetjew, Nadia Rostam, Anthony A Hyman

Nat Commun· December 2024

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Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates.
Xiao Yan, David Kuster, Priyesh Mohanty, Jik Nijssen, Karina Pombo-García, Anthony A Hyman

bioRxiv· May 2024

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Solutes unmask differences in clustering versus phase separation of FET proteins.
Mrityunjoy Kar, Laura T Vogel, Gaurav Chauhan, Suren Felekyan, Hannes Ausserwöger, Anthony A Hyman

Nat Commun· May 2024

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Local and dynamic regulation of neuronal glycolysis in vivo.
Aaron D Wolfe, John N Koberstein, Chadwick B Smith, Melissa L Stewart, Ian J Gonzalez, Anthony A Hyman

Proc Natl Acad Sci U S A· January 2024

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Different Low-complexity Regions of SFPQ Play Distinct Roles in the Formation of Biomolecular Condensates.
Andrew C Marshall, Jerry Cummins, Simon Kobelke, Tianyi Zhu, Jocelyn Widagdo, Anthony Hyman

J Mol Biol· December 2023

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Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions.
Mrityunjoy Kar, Laura T Vogel, Gaurav Chauhan, Hannes Ausserwöger, Timothy J Welsh, Anthony A Hyman

Res Sq· September 2023

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Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions.
Mrityunjoy Kar, Laura T Vogel, Gaurav Chauhan, Hannes Ausserwöger, Timothy J Welsh, Anthony A Hyman

bioRxiv· August 2023

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Local and dynamic regulation of neuronal glycolysis .
Aaron D Wolfe, John N Koberstein, Chadwick B Smith, Melissa L Stewart, Marc Hammarlund, Anthony Hyman

bioRxiv· August 2023

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CD-CODE: crowdsourcing condensate database and encyclopedia.
Nadia Rostam, Soumyadeep Ghosh, Chi Fung Willis Chow, Anna Hadarovich, Cedric Landerer, Anthony A Hyman

Nat Methods· May 2023

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Molecular mechanisms of stress-induced reactivation in mumps virus condensates.
Xiaojie Zhang, Sindhuja Sridharan, Ievgeniia Zagoriy, Christina Eugster Oegema, Cyan Ching, Anthony A Hyman

Cell· April 2023

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Biomolecular condensate phase diagrams with a combinatorial microdroplet platform.
William E Arter, Runzhang Qi, Nadia A Erkamp, Georg Krainer, Kieran Didi, Anthony A Hyman

Nat Commun· December 2022

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