Publications by authors named "Antoine Forget"

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Combinatorial protein engineering identifies potent CRISPR activators with reduced toxicity.
Marla Giddins, Alexander F Kratz, Mark B De Los Santos, Antoine Forget, Richa Tiwari

Nat Commun· November 2025

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A transcriptomic, proteomic, and functional genetic atlas dissects neurofibromin function in the peripheral nervous system.
Harish N Vasudevan, Nadia Arang, Maria Sacconi Nunez, Patrick Kennedy, Emily Payne, Antoine Forget

Proc Natl Acad Sci U S A· July 2025

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Sonic hedgehog medulloblastomas are dependent on Netrin-1 for survival.
Julie Talbot, Joanna Fombonne, Jacob Torrejon, Benjamin R Babcock, Leon F McSwain, Antoine Forget

Nat Commun· June 2025

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A PERTURBATION CELL ATLAS OF HUMAN INDUCED PLURIPOTENT STEM CELLS.
Sami Nourreddine, Yesh Doctor, Amir Dailamy, Antoine Forget, Yi-Hung Lee

bioRxiv· November 2024

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Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule.
Lois M Kelly, Justine C Rutter, Kevin H Lin, Frank Ling, Matthieu Duchmann, Antoine Forget

Nat Cancer· July 2024

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Cell Maps for Artificial Intelligence: AI-Ready Maps of Human Cell Architecture from Disease-Relevant Cell Lines.
Timothy Clark, Jillian Mohan, Leah Schaffer, Kirsten Obernier, Sadnan Al Manir, Antoine Forget

bioRxiv· May 2024

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Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3.
Hayarpi Torosyan, Michael D Paul, Antoine Forget, Megan Lo, Devan Diwanji

Nat Commun· June 2023

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P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia.
Kevin H Lin, Justine C Rutter, Abigail Xie, Shane T Killarney, Camille Vaganay, Antoine Forget

Nat Cancer· July 2022

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The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.
Jasmin Bartl, Marco Zanini, Flavia Bernardi, Antoine Forget, Lena Blümel

Nat Commun· July 2022

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Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia.
Bryann Pardieu, Justine Pasanisi, Frank Ling, Reinaldo Dal Bello, Justine Penneroux, Antoine Forget

Leukemia· June 2022

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Target Discovery for Host-Directed Antiviral Therapies: Application of Proteomics Approaches.
Merve Cakir, Kirsten Obernier, Antoine Forget, Nevan J Krogan

mSystems· October 2021

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Excitatory granule neuron precursors orchestrate laminar localization and differentiation of cerebellar inhibitory interneuron subtypes.
Christelle Cadilhac, Isabelle Bachy, Antoine Forget, David J Hodson, Céline Jahannault-Talignani

Cell Rep· March 2021

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The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies.
Angela Su, Frank Ling, Camille Vaganay, Gaetano Sodaro, Chaïma Benaksas, Antoine Forget

Cancer Discov· December 2020

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An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate.
Jamie Zagozewski, Ghazaleh M Shahriary, Ludivine Coudière Morrison, Olivier Saulnier, Margaret Stromecki, Antoine Forget

Nat Commun· July 2020

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Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer.
Kevin H Lin, Justine C Rutter, Abigail Xie, Bryann Pardieu, Emily T Winn, Antoine Forget

Nat Genet· April 2020

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Germline Elongator mutations in Sonic Hedgehog medulloblastoma.
Sebastian M Waszak, Giles W Robinson, Brian L Gudenas, Kyle S Smith, Antoine Forget

Nature· April 2020

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Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.
Hiromichi Suzuki, Sachin A Kumar, Shimin Shuai, Ander Diaz-Navarro, Ana Gutierrez-Fernandez, Antoine Forget

Nature· October 2019

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An autocrine ActivinB mechanism drives TGFβ/Activin signaling in Group 3 medulloblastoma.
Morgane Morabito, Magalie Larcher, Florence Mg Cavalli, Chloé Foray, Antoine Forget

EMBO Mol Med· August 2019

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Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation.
Chia-Hsiang Chang, Marco Zanini, Hamasseh Shirvani, Jia-Shing Cheng, Hua Yu, Antoine Forget

Dev Cell· January 2019

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Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling.
Antoine Forget, Loredana Martignetti, Stéphanie Puget, Laurence Calzone, Sebastian Brabetz

Cancer Cell· September 2018

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ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas.
Katie B Grausam, Samuel D R Dooyema, Laure Bihannic, Hasitha Premathilake, A Sorana Morrissy, Antoine Forget

Cancer Res· July 2017

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A review of computational approaches detecting microRNAs involved in cancer.
Laura Cantini, Michele Caselle, Antoine Forget, Andrei Zinovyev, Emmanuel Barillot

Front Biosci (Landmark Ed)· June 2017

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Return to quiescence of mouse neural stem cells by degradation of a proactivation protein.
Noelia Urbán, Debbie L C van den Berg, Antoine Forget, Jimena Andersen, Jeroen A A Demmers

Science· July 2016

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Shh signaling protects Atoh1 from degradation mediated by the E3 ubiquitin ligase Huwe1 in neural precursors.
Antoine Forget, Laure Bihannic, Sara Maria Cigna, Coralie Lefevre, Marc Remke

Dev Cell· June 2014

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The Hippo kinase promotes Scalloped cytoplasmic localization independently of Warts in a CRM1/Exportin1-dependent manner in Drosophila.
Julie Cagliero, Antoine Forget, Enrico Daldello, Joël Silber, Alain Zider

FASEB J· April 2013

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