Publications by authors named "Antoni Riera"

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TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1 macrophages.
Ana Henriques, Maria Salvany-Celades, Paula Nieto, Sergio Palomo-Ponce, Marta Sevillano, Antoni Riera

Nat Genet· December 2025

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Chiral CNN pincer Ir(III)-H complexes. Transient ligand and counterion influences in the asymmetric hydrogenation of imines and quinolines.
Yisong Wen, Albert Cabré, Jordi Benet-Buchholz, Antoni Riera, Xavier Verdaguer

Dalton Trans· July 2025

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The PIN1-p38-CtIP signalling axis protects stalled replication forks from deleterious degradation.
Francesca Vivalda, Marco Gatti, Letizia Manfredi, Hülya Dogan, Antonio Porro, Antoni Riera

Nucleic Acids Res· April 2025

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MAdPHOS, a P-Stereogenic Aminodiphosphane Ligand with Adamantyl Groups: Synthesis, NH/PH Tautomerism, and Rhodium and Nickel Complexes.
Marina Bellido, Helena Solé-Àvila, Martí Sidro, Arnald Grabulosa, Xavier Verdaguer, Antoni Riera

J Org Chem· February 2025

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New Potent Inhibitor of Transforming Growth Factor-Beta (TGFβ) Signaling that is Efficacious against Microsatellite Stable Colorectal Cancer Metastasis in Combination with Immune Checkpoint Therapy in Mice.
Daniele V F Tauriello, Elena Sancho, Daniel Byrom, Carolina Sanchez-Zarzalejo, Maria Salvany, Antoni Riera

ACS Pharmacol Transl Sci· January 2025

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Highly Enantioselective Synthesis of 3,3-Diarylpropyl Amines and 4-Aryl Tetrahydroquinolines via Ir-Catalyzed Asymmetric Hydrogenation.
Martí Sidro, Clara García-Mateos, Pep Rojo, Yisong Wen, Antoni Riera

Org Lett· December 2024

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Cyclometallated Imides as Templates for the H-Bond Directed Iridium-Catalyzed Asymmetric Hydrogenation of N-Methyl, N-Alkyl and N-Aryl Imines.
Yisong Wen, Marc Fernández-Sabaté, Agustí Lledós, Giuseppe Sciortino, James Eills, Antoni Riera

Angew Chem Int Ed Engl· June 2024

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Discovery and Mechanistic Elucidation of NQO1-Bioactivatable Small Molecules That Overcome Resistance to Degraders.
Bárbara M G Barbosa, Aikaterini Sfyaki, Sergi Rafael, Ferran José-Duran, Joan Pous, Antoni Riera

Angew Chem Int Ed Engl· March 2024

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MAF amplification licenses ERα through epigenetic remodelling to drive breast cancer metastasis.
Alicia Llorente, María Teresa Blasco, Irene Espuny, Marc Guiu, Cecilia Ballaré, Antoni Riera

Nat Cell Biol· December 2023

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Rational optimization of a transcription factor activation domain inhibitor.
Shaon Basu, Paula Martínez-Cristóbal, Marta Frigolé-Vivas, Mireia Pesarrodona, Michael Lewis, Antoni Riera

Nat Struct Mol Biol· December 2023

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Enantioselective Ir-Catalyzed Hydrogenation of Terminal Homoallyl Sulfones: Total Synthesis of (-)-Curcumene.
Marina Bellido, Carlos Riego-Mejías, Alejandro Diaz-Moreno, Xavier Verdaguer, Antoni Riera

Org Lett· March 2023

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P-Stereogenic Ir-MaxPHOX: A Step toward Privileged Catalysts for Asymmetric Hydrogenation of Nonchelating Olefins.
Maria Biosca, Pol de la Cruz-Sánchez, Jorge Faiges, Jèssica Margalef, Ernest Salomó, Antoni Riera

ACS Catal· March 2023

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Synthesis and Biological Activity of a VHL-Based PROTAC Specific for p38α.
Mónica Cubillos-Rojas, Guillem Loren, Yusuf Z Hakim, Xavier Verdaguer, Antoni Riera

Cancers (Basel)· January 2023

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Design and optimization of oestrogen receptor PROTACs based on 4-hydroxytamoxifen.
Guillem Loren, Irene Espuny, Alicia Llorente, Craig Donoghue, Xavier Verdaguer, Antoni Riera

Eur J Med Chem· December 2022

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Iridium-Catalyzed Asymmetric Hydrogenation of 2,3-Diarylallyl Amines with a Threonine-Derived P-Stereogenic Ligand for the Synthesis of Tetrahydroquinolines and Tetrahydroisoquinolines.
Pep Rojo, Medea Molinari, Albert Cabré, Clara García-Mateos, Antoni Riera

Angew Chem Int Ed Engl· July 2022

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Amino acids with fluorescent tetrazine ethers as bioorthogonal handles for peptide modification.
Enric Ros, Marina Bellido, Joan A Matarin, Albert Gallen, Manuel Martínez, Antoni Riera

RSC Adv· May 2022

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Recent Advances in the Enantioselective Synthesis of Chiral Amines via Transition Metal-Catalyzed Asymmetric Hydrogenation.
Albert Cabré, Xavier Verdaguer, Antoni Riera

Chem Rev· January 2022

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BOM-Phosphinite as an Electrophilic P-Stereogenic Transfer Reagent for the Synthesis of Bulky Phosphines: Synthesis of -Butyl(3,5-di--butylphenyl)BisP.
Pep Rojo, Antoni Riera, Xavier Verdaguer

Org Lett· June 2021

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Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease.
Álvaro Rol, Toni Todorovski, Pau Martin-Malpartida, Anna Escolà, Elena Gonzalez-Rey, Antoni Riera

Nat Commun· March 2021

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Somatostatin, an Binder to Aβ Oligomers, Binds to βPFO Tetramers.
Eduard Puig, James Tolchard, Antoni Riera, Natàlia Carulla

ACS Chem Neurosci· October 2020

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Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation.
Craig Donoghue, Monica Cubillos-Rojas, Nuria Gutierrez-Prat, Carolina Sanchez-Zarzalejo, Xavier Verdaguer, Antoni Riera

Eur J Med Chem· September 2020

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Synthesis of 3-alkyl-6-methyl-1,2,4,5-tetrazines via a Sonogashira-type cross-coupling reaction.
Enric Ros, Amparo Prades, Dominique Forson, Jacqueline Smyth, Xavier Verdaguer, Antoni Riera

Chem Commun (Camb)· September 2020

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Catalytic Regioselective Isomerization of 2,2-Disubstituted Oxetanes to Homoallylic Alcohols.
Albert Cabré, Sergi Rafael, Giuseppe Sciortino, Gregori Ujaque, Xavier Verdaguer, Antoni Riera

Angew Chem Int Ed Engl· May 2020

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Synthesis and Application of 3-Bromo-1,2,4,5-Tetrazine for Protein Labeling to Trigger Click-to-Release Biorthogonal Reactions.
Enric Ros, Marina Bellido, Xavier Verdaguer, Lluís Ribas de Pouplana, Antoni Riera

Bioconjug Chem· March 2020

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P-Stereogenic Amino-Phosphines as Chiral Ligands: From Privileged Intermediates to Asymmetric Catalysis.
Albert Cabré, Antoni Riera, Xavier Verdaguer

Acc Chem Res· March 2020

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