Publications by authors named "Aparna Vasanthakumar"

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Developing Topics.
Michael Vacher, Tenielle Porter, Lidija Milicic, Eleanor K O'Brien, Milcent Tsvangiray, Aparna Vasanthakumar

Alzheimers Dement· December 2025

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Proteomic signatures of the ε and ε genetic variants and Alzheimer's disease.
Lina Lu, Alexa Pichet Binette, Ines Hristovska, Shorena Janelidze, Bart Smets, Aparna Vasanthakumar

medRxiv· August 2025

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ADNI Private Partners Scientific Board (PPSB) Diversity, Equity, and Inclusion (DE&I) Working Group: A new collaboration that crosses boundaries for industry, academia, and under-represented patients.
Ruth Croney, Emil Fristed, Donna Masterman, Martine Meyer, Pallavi Sachdev, Aparna Vasanthakumar

Alzheimers Dement· January 2025

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CYP1B1-RMDN2 Alzheimer's disease endophenotype locus identified for cerebral tau PET.
Kwangsik Nho, Shannon L Risacher, Liana G Apostolova, Paula J Bice, Jared R Brosch, Aparna Vasanthakumar

Nat Commun· September 2024

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Navitoclax safety, tolerability, and effect on biomarkers of senescence and neurodegeneration in aged nonhuman primates.
Edward F Greenberg, Martin J Voorbach, Alexandra Smith, David R Reuter, Yuchuan Zhuang, Aparna Vasanthakumar

Heliyon· August 2024

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Diversity of CFTR variants across ancestries characterized using 454,727 UK biobank whole exome sequences.
Justin E Ideozu, Mengzhen Liu, Bridget M Riley-Gillis, Sri R Paladugu, Fedik Rahimov, Aparna Vasanthakumar

Genome Med· March 2024

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The Alzheimer's Disease Neuroimaging Initiative and the role and contributions of the Private Partners Scientific Board (PPSB).
Bruce Albala, Eline Appelmans, Ramona Burress, Susan De Santi, Theresa Devins, Aparna Vasanthakumar

Alzheimers Dement· January 2024

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PINNED: identifying characteristics of druggable human proteins using an interpretable neural network.
Michael Cunningham, Danielle Pins, Zoltán Dezső, Maricel Torrent, Aparna Vasanthakumar

J Cheminform· July 2023

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Novel Alzheimer's disease locus identified by genome-wide association analysis of cerebral tau deposition on PET.
Kwangsik Nho, Shannon L Risacher, Liana Apostolova, Paula J Bice, Jared Brosch, Aparna Vasanthakumar

medRxiv· March 2023

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Editorial: Women in science: Genetics.
Jaira Ferreira de Vasconcellos, Malak Abedalthagafi, Silvia Calo, Rana Dajani, Zodwa Dlamini, Aparna Vasanthakumar

Front Genet· October 2022

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Integrative analysis of DNA methylation and gene expression identifies genes associated with biological aging in Alzheimer's disease.
Bo-Hyun Kim, Aparna Vasanthakumar, Qingqin S Li, Kelly N H Nudelman, Shannon L Risacher

Alzheimers Dement (Amst)· September 2022

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Association of peripheral blood DNA methylation level with Alzheimer's disease progression.
Qingqin S Li, Aparna Vasanthakumar, Justin W Davis, Kenneth B Idler, Kwangsik Nho

Clin Epigenetics· October 2021

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Differential translational control of 5' IRE-containing mRNA in response to dietary iron deficiency and acute iron overload.
Kerry R Garza, Stephen L Clarke, Yi-Hsuan Ho, Matthew D Bruss, Aparna Vasanthakumar

Metallomics· December 2020

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Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease.
Aparna Vasanthakumar, Justin W Davis, Kenneth Idler, Jeffrey F Waring, Elizabeth Asque

Clin Epigenetics· June 2020

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Reduced ITPase activity and favorable IL28B genetic variant protect against ribavirin-induced anemia in interferon-free regimens.
Aparna Vasanthakumar, Justin W Davis, Manal Abunimeh, Jonas Söderholm, Jiuhong Zha

PLoS One· November 2018

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Erratum to "5-hydroxymethylcytosine in cancer: Significance in diagnosis and therapy" [Cancer Genet 208 (2015):167-177].
Aparna Vasanthakumar, Lucy A Godley

Cancer Genet· April 2016

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Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice.
Aparna Vasanthakumar, Stephen Arnovitz, Rafael Marquez, Janet Lepore, George Rafidi

Blood· January 2016

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Epigenetic Control of Apolipoprotein E Expression Mediates Gender-Specific Hematopoietic Regulation.
Aparna Vasanthakumar, Hayley Zullow, Janet B Lepore, Kenya Thomas, Natalie Young

Stem Cells· December 2015

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DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID.
Pilar M Dominguez, Matt Teater, Nyasha Chambwe, Matthias Kormaksson, David Redmond, Aparna Vasanthakumar

Cell Rep· September 2015

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TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.
Jumpei Yamazaki, Jaroslav Jelinek, Yue Lu, Matteo Cesaroni, Jozef Madzo, Aparna Vasanthakumar

Cancer Res· July 2015

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5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy.
Aparna Vasanthakumar, Lucy A Godley

Cancer Genet· May 2015

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DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Raajit Rampal, Altuna Alkalin, Jozef Madzo, Aparna Vasanthakumar, Elodie Pronier

Cell Rep· December 2014

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TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.
Christopher J Mariani, Aparna Vasanthakumar, Jozef Madzo, Ali Yesilkanal, Tushar Bhagat

Cell Rep· June 2014

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On the origin of leukemic species.
Aparna Vasanthakumar, Lucy A Godley

Cell Stem Cell· April 2014

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Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
Jozef Madzo, Hui Liu, Alexis Rodriguez, Aparna Vasanthakumar, Sriram Sundaravel

Cell Rep· January 2014

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