Publications by authors named "April A Apfelbaum"

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Multi-pronged analysis of pediatric low-grade glioma and ganglioglioma reveals a unique tumor microenvironment associated with BRAF alterations.
Shadi Zahedi, Kent Riemondy, Tian Liu, Andrea M Griesinger, Andrew M Donson, April A Apfelbaum

Brain Pathol· November 2025

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Author Correction: A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas.
April A Apfelbaum, Eric Morin, Dominik Sturm, Georges Ayoub, Jeromy DiGiacomo

Nat Commun· October 2025

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Multimodal single-cell analyses reveal distinct fusion-regulated transcriptional programs in Ewing sarcoma.
Olivia G Waltner, April A Apfelbaum, Emma D Wrenn, Shruti S Bhise, Sami B Kanaan

bioRxiv· September 2025

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A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas.
April A Apfelbaum, Eric Morin, Dominik Sturm, Georges Ayoub, Jeromy DiGiacomo

Nat Commun· July 2025

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Autocrine TGFβ2 enforces a transcriptionally hybrid cell state in Ewing sarcoma.
Emma D Wrenn, Jacob C Harris, April A Apfelbaum, Jonah R Valenti, Patricia A Lipson

bioRxiv· June 2025

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Cancer-Associated Fibroblast-Like Tumor Cells Remodel the Ewing Sarcoma Tumor Microenvironment.
Emma D Wrenn, April A Apfelbaum, Erin R Rudzinski, Xuemei Deng, Wei Jiang

Clin Cancer Res· December 2023

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β-Catenin-Driven Differentiation Is a Tissue-Specific Epigenetic Vulnerability in Adrenal Cancer.
Dipika R Mohan, Kleiton S Borges, Isabella Finco, Christopher R LaPensee, Juilee Rege, April A Apfelbaum

Cancer Res· July 2023

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Carcinoma-associated fibroblast-like tumor cells remodel the Ewing sarcoma tumor microenvironment.
Emma D Wrenn, April A Apfelbaum, Erin R Rudzinski, Xuemei Deng, Wei Jiang

bioRxiv· April 2023

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Oncogenic role for an EWS-FLI1 suppressor.
April A Apfelbaum, Elizabeth R Lawlor

Nat Cell Biol· February 2023

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The importance of fusion protein activity in Ewing sarcoma and the cell intrinsic and extrinsic factors that regulate it: A review.
April A Apfelbaum, Emma D Wrenn, Elizabeth R Lawlor

Front Oncol· November 2022

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EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma.
April A Apfelbaum, Feinan Wu, Allegra G Hawkins, Brian Magnuson, Jennifer A Jiménez

Clin Cancer Res· October 2022

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Systemic Delivery of an Adjuvant CXCR4-CXCL12 Signaling Inhibitor Encapsulated in Synthetic Protein Nanoparticles for Glioma Immunotherapy.
Mahmoud S Alghamri, Kaushik Banerjee, Anzar A Mujeeb, Ava Mauser, Ayman Taher, April A Apfelbaum

ACS Nano· June 2022

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EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma.
Jennifer A Jiménez, April A Apfelbaum, Allegra G Hawkins, Laurie K Svoboda, Abhijay Kumar

Mol Cancer Res· July 2021

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A transcriptomics approach uncovers novel roles for poly(ADP-ribosyl)ation in the basal defense response in Arabidopsis thaliana.
Amy G Briggs, Lori C Adams-Phillips, Brian D Keppler, Sophia G Zebell, Kyle C Arend, April A Apfelbaum

PLoS One· February 2018

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A Bifunctional MAPK/PI3K Antagonist for Inhibition of Tumor Growth and Metastasis.
Stefanie Galbán, April A Apfelbaum, Carlos Espinoza, Kevin Heist, Henry Haley

Mol Cancer Ther· November 2017

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Structure-Guided Design and Initial Studies of a Bifunctional MEK/PI3K Inhibitor (ST-168).
Marcian E Van Dort, Stefanie Galbán, Charles A Nino, Hao Hong, April A Apfelbaum

ACS Med Chem Lett· August 2017

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