Publications by authors named "April Pawluk"

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Site-specific DNA insertion into the human genome with engineered recombinases.
Alison Fanton, Liam J Bartie, Juliana Q Martins, Vincent Q Tran, Laine Goudy, April Pawluk

Nat Biotechnol· November 2025

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Bridge RNAs direct programmable recombination of target and donor DNA.
Matthew G Durrant, Nicholas T Perry, James J Pai, Aditya R Jangid, Januka S Athukoralage, April Pawluk

Nature· June 2024

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Structural mechanism of bridge RNA-guided recombination.
Masahiro Hiraizumi, Nicholas T Perry, Matthew G Durrant, Teppei Soma, Naoto Nagahata, April Pawluk

Nature· June 2024

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Bridge RNAs direct modular and programmable recombination of target and donor DNA.
Matthew G Durrant, Nicholas T Perry, James J Pai, Aditya R Jangid, Januka S Athukoralage, April Pawluk

bioRxiv· January 2024

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Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting.
Jingyi Wei, Peter Lotfy, Kian Faizi, Sara Baungaard, Emily Gibson, April Pawluk

Cell Syst· December 2023

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Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes.
Kelsey N Thompson, Kevin S Bonham, Nicholas E Ilott, Graham J Britton, Paula Colmenero, April Pawluk

Sci Transl Med· July 2023

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Discovery of bioactive microbial gene products in inflammatory bowel disease.
Yancong Zhang, Amrisha Bhosle, Sena Bae, Lauren J McIver, Gleb Pishchany, April Pawluk

Nature· June 2022

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Anti-CRISPR AcrIE2 Binds the Type I-E CRISPR-Cas Complex But Does Not Block DNA Binding.
Marios Mejdani, April Pawluk, Karen L Maxwell, Alan R Davidson

J Mol Biol· February 2021

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Finding Common Ground.
April Pawluk

Cell· May 2019

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Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins.
Jooyoung Lee, Aamir Mir, Alireza Edraki, Bianca Garcia, Nadia Amrani, April Pawluk

mBio· December 2018

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CRISPR: No Sign of Slowing Down.
April Pawluk

Cell· August 2018

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Breaking the Rules.
April Pawluk

Cell· May 2018

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Anti-CRISPR: discovery, mechanism and function.
April Pawluk, Alan R Davidson, Karen L Maxwell

Nat Rev Microbiol· January 2018

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Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein.
April Pawluk, Megha Shah, Marios Mejdani, Charles Calmettes, Trevor F Moraes

mBio· December 2017

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Tiny Answers to Big Questions.
April Pawluk

Cell· July 2017

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Naturally Occurring Off-Switches for CRISPR-Cas9.
April Pawluk, Nadia Amrani, Yan Zhang, Bianca Garcia, Yurima Hidalgo-Reyes

Cell· December 2016

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Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species.
April Pawluk, Raymond H J Staals, Corinda Taylor, Bridget N J Watson, Senjuti Saha

Nat Microbiol· June 2016

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A new group of phage anti-CRISPR genes inhibits the type I-E CRISPR-Cas system of Pseudomonas aeruginosa.
April Pawluk, Joseph Bondy-Denomy, Vivian H W Cheung, Karen L Maxwell, Alan R Davidson

mBio· April 2014

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Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system.
Joe Bondy-Denomy, April Pawluk, Karen L Maxwell, Alan R Davidson

Nature· January 2013

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