Publications by authors named "Aprile Pilon"

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Maternal Smoking and CC-16: Implications for Lung Development and COPD Across the Lifespan.
Joselyn Rojas-Quintero, Rosa Faner, Chia-Ying Chiu, Jeff T Kue, Yun Zhang, Aprile L Pilon

Am J Respir Crit Care Med· October 2025

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CC16 augmentation reduces exaggerated COPD-like disease in Cc16-deficient mice.
Joselyn Rojas-Quintero, Maria Eugenia Laucho-Contreras, Xiaoyun Wang, Quynh-Anh Fucci, Patrick R Burkett, Aprile L Pilon

JCI Insight· March 2023

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Emerging role of an immunomodulatory protein secretoglobin 3A2 in human diseases.
Shioko Kimura, Shigetoshi Yokoyama, Aprile L Pilon, Reiko Kurotani

Pharmacol Ther· August 2022

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Club Cell Secretory Protein (CCSP) is Reduced in Hospitalized Chronic Obstructive Pulmonary Disease (COPD) Exacerbations.
Arianne K Baldomero, Ken M Kunisaki, John Connett, Aprile Pilon, Chris H Wendt

Int J Chron Obstruct Pulmon Dis· June 2021

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CC16 Binding to αβ Integrin Protects against Infection.
Michael D L Johnson, Usir S Younis, Sanjay V Menghani, Kenneth J Addison, Michael Whalen, Aprile L Pilon

Am J Respir Crit Care Med· June 2021

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Secretoglobin 3A2 eliminates human cancer cells through pyroptosis.
Shigetoshi Yokoyama, Shun Nakayama, Lei Xu, Aprile L Pilon, Shioko Kimura

Cell Death Discov· January 2021

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Club Cell Protein, CC10, Attenuates Acute Respiratory Distress Syndrome Induced by Smoke Inhalation.
Ernesto Lopez, Osamu Fujiwara, Christina Nelson, Melissa E Winn, Richard S Clayton, Aprile L Pilon

Shock· March 2020

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The role of recombinant human CC10 in the prevention of chronic pulmonary insufficiency of prematurity.
Jonathan M Davis, Aprile L Pilon, Jeffrey Shenberger, Janis L Breeze, Norma Terrin

Pediatr Res· August 2019

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A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death.
Shigetoshi Yokoyama, Yan Cai, Miyuki Murata, Takeshi Tomita, Mitsuhiro Yoneda, Aprile L Pilon

Elife· December 2018

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Evaluation of Club Cell 10-kDa Protein (CC10) Levels in Full-Term Infants.
Nasim Gorji, Aprile L Pilon, Melissa E Winn, Morgan Newsome, Jonathan M Davis

Neonatology· December 2017

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Club Cell Protein 16 (CC16) Augmentation: A Potential Disease-modifying Approach for Chronic Obstructive Pulmonary Disease (COPD).
Maria E Laucho-Contreras, Francesca Polverino, Yohannes Tesfaigzi, Aprile Pilon, Bartolome R Celli

Expert Opin Ther Targets· July 2016

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Protective role for club cell secretory protein-16 (CC16) in the development of COPD.
Maria E Laucho-Contreras, Francesca Polverino, Kushagra Gupta, Katherine L Taylor, Emer Kelly, Aprile L Pilon

Eur Respir J· June 2015

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Preclinical evaluation of human secretoglobin 3A2 in mouse models of lung development and fibrosis.
Yan Cai, Melissa E Winn, John K Zehmer, William K Gillette, Jacek T Lubkowski, Aprile L Pilon

Am J Physiol Lung Cell Mol Physiol· January 2014

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Spiral counter-current chromatography of small molecules, peptides and proteins using the spiral tubing support rotor.
Martha Knight, Thomas M Finn, John Zehmer, Adam Clayton, Aprile Pilon

J Chromatogr A· September 2011

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Recombinant human Clara cell secretory protein treatment increases lung mRNA expression of surfactant proteins and vascular endothelial growth factor in a premature lamb model of respiratory distress syndrome.
Marla R Wolfson, Vicky L Funanage, Susan M Kirwin, Aprile L Pilon, Beth N Shashikant

Am J Perinatol· November 2008

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Higher levels of the anti-inflammatory protein CC10 are associated with improvement in bronchial dysplasia and sputum cytometric assessment in individuals at high risk for lung cancer.
Jiping Chen, Stephen Lam, Aprile Pilon, Annette McWilliams, Calum Macaulay

Clin Cancer Res· March 2008

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CC10 reduces inflammation in meconium aspiration syndrome in newborn piglets.
Robert M Angert, Aprile L Pilon, Darrin Chester, Jonathan M Davis

Pediatr Res· December 2007

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The association between the anti-inflammatory protein CC10 and smoking status among participants in a chemoprevention trial.
Jiping Chen, Stephen Lam, Aprile Pilon, Annette McWilliams, James Melby

Cancer Epidemiol Biomarkers Prev· March 2007

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Effects of recombinant Clara cell secretory protein (rhCC10) on inflammatory-related matrix metalloproteinase activity in a preterm lamb model of neonatal respiratory distress.
Thomas L Miller, Beth N Shashikant, Aprile L Pilon, Richard A Pierce, Thomas H Shaffer

Pediatr Crit Care Med· January 2007

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Effects of an intratracheally delivered anti-inflammatory protein (rhCC10) on physiological and lung structural indices in a juvenile model of acute lung injury.
Thomas L Miller, Beth N Shashikant, Aprile L Pilon, Richard A Pierce, Thomas H Shaffer

Biol Neonate· May 2006

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Recombinant human uteroglobin/CC10 inhibits the adhesion and migration of primary human endothelial cells via specific and saturable binding to fibronectin.
Giovanni Antico, Mark W Lingen, Antonella Sassano, James Melby, Richard W Welch, Aprile L Pilon

J Cell Physiol· May 2006

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Dose response to rhCC10-augmented surfactant therapy in a lamb model of infant respiratory distress syndrome: physiological, inflammatory, and kinetic profiles.
Beth N Shashikant, Thomas L Miller, Richard W Welch, Aprile L Pilon, Thomas H Shaffer

J Appl Physiol (1985)· December 2005

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Recombinant human Clara cell secretory protein in acute lung injury of the rabbit: effect of route of administration.
Thomas L Miller, Beth N Shashikant, James M Melby, Aprile L Pilon, Thomas H Shaffer

Pediatr Crit Care Med· November 2005

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The safety, pharmacokinetics, and anti-inflammatory effects of intratracheal recombinant human Clara cell protein in premature infants with respiratory distress syndrome.
Carolyn R Levine, Ira H Gewolb, Kristen Allen, Richard W Welch, James M Melby, Aprile L Pilon

Pediatr Res· July 2005

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Clara cell 10-KDA protein inhibits endotoxin-induced airway contraction in isolated perfused rat lungs.
Ali Reza Nosratabadi, Anders G Ljungman, Mats Lindahl, Richard Welch, Aprile Pilon

Exp Lung Res· June 2004

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