Publications by authors named "Asfar Azmi"

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PCNA Inhibition Enhances the Antitumor Activity of KRAS-Targeted Therapies in Pancreatic Cancer.
Sahar F Bannoura, Husain Yar Khan, Amro Aboukameel, Yin Wan, Bin Bao, Asfar S Azmi

bioRxiv· December 2025

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An Update on Novel Pharmacotherapies for the Treatment of Neuroendocrine Tumors.
Khalil Choucair, Roupen Odabashian, Sushmita Nanja Reddy, Asfar Sohail Azmi, Muhammad Wasif Saif

Int J Mol Sci· November 2025

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Targeting KRAS mutations: orchestrating cancer evolution and therapeutic challenges.
Khalil Choucair, Hafsa Imtiaz, Md Hafiz Uddin, Misako Nagasaka, Mohammad Najeeb Al-Hallak, Asfar S Azmi

Signal Transduct Target Ther· November 2025

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Co-targeting KRAS and Exportin1 as an effective therapeutic strategy for KRASG12D mutant pancreatic ductal adenocarcinoma.
Husain Yar Khan, Mohammed Najeeb Al Hallak, Amro Aboukameel, Sahar F Bannoura, Md Hafiz Uddin, Asfar S Azmi

bioRxiv· November 2025

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Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields.
Hugo Jimenez, Denise Gibo, Sambad Sharma, Michael Pennison, Lance D Miller, Asfar Azmi

Oncotarget· October 2025

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Assessment of Online Patient Education Materials for Pancreatic Neuroendocrine Tumors.
Brendan Dolan, Miguel Tzita, Miguel Tobon, Najeeb Al Hallak, Asfar Azmi

Am Surg· September 2025

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XPO1 inhibition in KRAS-mutant cancers: time for clinical trials but how?
Misako Nagasaka, Husain Y Khan, Faustine Luo, Mohammed Najeeb Al-Hallak, Muhammad Wasif Saif, Asfar S Azmi

Transl Lung Cancer Res· August 2025

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Multiomic Characterization of and Expression and Their Association With Molecular Alterations, Immune Phenotypes, and Cancer Outcomes.
Misako Nagasaka, Brian Warnecke, Sai-Hong Ignatius Ou, Sahar F Bannoura, Chul Kim, Asfar S Azmi

JCO Oncol Adv· May 2025

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Molecular Characterization and Clinical Outcomes of Pancreatic Neuroendocrine Neoplasms Harboring PAK4-NAMPT Alterations.
Ibrahim Azar, Husain Yar Khan, Sahar F Bannoura, Nishant Gandhi, Md Hafiz Uddin, Asfar S Azmi

JCO Oncol Adv· May 2025

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ADT-1004: a first-in-class, oral pan-RAS inhibitor with robust antitumor activity in preclinical models of pancreatic ductal adenocarcinoma.
Dhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh, Julienne L Carstens, Jeremy B Foote, Asfar S Azmi

Mol Cancer· March 2025

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Association between cannabis use and clinical outcomes in patients with solid malignancies receiving immune checkpoint inhibitors.
Tarik Hadid, Adam Biedny, Hirva Mamdani, Asfar Azmi, Seongho Kim

Ther Adv Vaccines Immunother· December 2024

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RCC1 regulation of subcellular protein localization via Ran GTPase drives pancreatic ductal adenocarcinoma growth.
Sahar F Bannoura, Amro Aboukameel, Husain Yar Khan, Md Hafiz Uddin, Hyejeong Jang, Asfar S Azmi

Cancer Lett· November 2024

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ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma.
Dhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh, Julienne L Carstens, Jeremy B Foote, Asfar S Azmi

bioRxiv· October 2024

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Multiomic Characterization and Molecular Profiling of Nuclear Protein in Testis Carcinoma.
Gianna Kroening, Jia Luo, Mark G Evans, Tolulope Adeyelu, Sai-Hong Ignatius Ou, Asfar S Azmi

JCO Precis Oncol· October 2024

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Targeting guanine nucleotide exchange factors for novel cancer drug discovery.
Sahar F Bannoura, Husain Yar Khan, Md Hafiz Uddin, Ramzi M Mohammad, Boris C Pasche, Asfar S Azmi

Expert Opin Drug Discov· August 2024

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Deciphering cellular plasticity in pancreatic cancer for effective treatments.
Md Hafiz Uddin, Dingqiang Zhang, Irfana Muqbil, Bassel F El-Rayes, Herbert Chen, Asfar S Azmi

Cancer Metastasis Rev· March 2024

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Individual ingredients of NP-101 (Thymoquinone formula) inhibit SARS-CoV-2 pseudovirus infection.
Abdelrahim Maen, Betul Gok Yavuz, Yehia I Mohamed, Abdullah Esmail, Jianming Lu, Asfar S Azmi

Front Pharmacol· February 2024

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Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRASG12C-Mutant Pancreatic and Lung Cancers.
Husain Yar Khan, Misako Nagasaka, Amro Aboukameel, Osama Alkhalili, Md Hafiz Uddin, Asfar S Azmi

Mol Cancer Ther· December 2023

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Molecular analysis of XPO1 inhibitor and gemcitabine-nab-paclitaxel combination in KPC pancreatic cancer mouse model.
Md Hafiz Uddin, Mohammad Najeeb Al-Hallak, Husain Yar Khan, Amro Aboukameel, Yiwei Li, Asfar S Azmi

Clin Transl Med· December 2023

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Regulator of Chromosome Condensation (RCC1) a novel therapeutic target in pancreatic ductal adenocarcinoma drives tumor progression via the c-Myc-RCC1-Ran axis.
Sahar F Bannoura, Amro Aboukameel, Husain Yar Khan, Md Hafiz Uddin, Hyejeong Jang, Asfar S Azmi

bioRxiv· December 2023

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Management of neuroendocrine tumor liver metastases.
Alex Harrelson, Rongzhi Wang, Addison Stewart, Clark Ingram, Andrea Gillis, Asfar Azmi

Am J Surg· November 2023

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Hepatocellular Carcinoma: Surveillance, Diagnosis, Evaluation and Management.
Jessica Elderkin, Najeeb Al Hallak, Asfar S Azmi, Hussein Aoun, Jeffrey Critchfield

Cancers (Basel)· October 2023

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Cancer cachexia research: coming of age.
Irfana Muqbil, Asfar S Azmi

Transl Lung Cancer Res· June 2023

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Penetrating the central nervous system sanctuary of KRAS, a target once thought "undruggable".
Misako Nagasaka, Asfar S Azmi

Transl Lung Cancer Res· April 2023

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Anticancer efficacy of KRASG12C inhibitors is potentiated by PAK4 inhibitor KPT9274 in preclinical models of KRASG12C mutant pancreatic and lung cancers.
Husain Yar Khan, Misako Nagasaka, Amro Aboukameel, Osama Alkhalili, Md Hafiz Uddin, Asfar S Azmi

bioRxiv· March 2023

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