Publications by authors named "Ashley Haddock"

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MT-125 inhibits non-muscle myosin IIA and IIB and prolongs survival in glioblastoma.
Rajappa S Kenchappa, Laszlo Radnai, Erica J Young, Natanael Zarco, Li Lin, Ashley Haddock

Cell· August 2025

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Resistance to spindle inhibitors in glioblastoma depends on STAT3 and therapy induced senescence.
Natanael Zarco, Athanassios Dovas, Virginea de Araujo Farias, Naveen K H Nagaiah, Ashley Haddock

iScience· December 2024

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PTEN deficiency induces an extrahepatic cholangitis-cholangiocarcinoma continuum via aurora kinase A in mice.
Yan Yang, Jiale Wang, Jianhua Wan, Qianqian Cheng, Zenong Cheng, Ashley N Haddock

J Hepatol· July 2024

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Resistance to Spindle Inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence.
Natanael Zarco, Athanassios Dovas, Virginea de Araujo Farias, Naveen Kh Nagaiah, Ashley Haddock

bioRxiv· June 2024

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Albumin promoter-driven FlpO expression induces efficient genetic recombination in mouse liver.
Xiaohui Zhu, Yan Yang, Dongfeng Feng, Oliver Wang, Jiaxiang Chen, Ashley N Haddock

Am J Physiol Gastrointest Liver Physiol· May 2024

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MT-125 Inhibits Non-Muscle Myosin IIA and IIB, Synergizes with Oncogenic Kinase Inhibitors, and Prolongs Survival in Glioblastoma.
Rajappa Kenchappa, Laszlo Radnai, Erica J Young, Natanael Zarco, Li Lin, Ashley Haddock

bioRxiv· April 2024

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A mouse model for high-efficient Flp-recombinase-mediated genetic manipulation in the pancreas.
Xiaohui Zhu, Jiaxiang Chen, Bin Wang, Lingxiang Wang, Jiale Wang, Ashley N Haddock

Pancreatology· September 2023

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Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma.
Rajappa S Kenchappa, Athanassios Dovas, Michael G Argenziano, Christian T Meyer, Lauren E Stopfer, Ashley Haddock

Cell Rep· June 2022

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Pancreas-specific CHRM3 activation causes pancreatitis in mice.
Jianhua Wan, Jiale Wang, Larry E Wagner, Oliver H Wang, Fu Gui, Ashley N Haddock

JCI Insight· September 2021

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Transgenic expression of human PRSS2 exacerbates pancreatitis in mice.
Jianhua Wan, Ashley Haddock, Brandy Edenfield, Baoan Ji, Yan Bi

Gut· November 2020

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Trypsin activity governs increased susceptibility to pancreatitis in mice expressing human PRSS1R122H.
Fu Gui, Yuebo Zhang, Jianhua Wan, Xianbao Zhan, Yao Yao, Ashley N Haddock

J Clin Invest· January 2020

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Ttc39c is upregulated during skeletal muscle atrophy and modulates ERK1/2 MAP kinase and hedgehog signaling.
Caleb S Hayes, Sydney A Labuzan, Jacob A Menke, Ashley N Haddock, David S Waddell

J Cell Physiol· December 2019

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Elevated intracellular trypsin exacerbates acute pancreatitis and chronic pancreatitis in mice.
Xianbao Zhan, Jianhua Wan, Guowei Zhang, Lele Song, Fu Gui, Ashley N Haddock

Am J Physiol Gastrointest Liver Physiol· June 2019

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Dual-specificity phosphatase 4 is upregulated during skeletal muscle atrophy and modulates extracellular signal-regulated kinase activity.
Ashley N Haddock, Sydney A Labuzan, Amy E Haynes, Caleb S Hayes, Karina M Kakareka

Am J Physiol Cell Physiol· April 2019

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Inhibition of miR-155 reduces impaired autophagy and improves prognosis in an experimental pancreatitis mouse model.
Jianhua Wan, Xiaoyu Yang, Yuping Ren, Xueyang Li, Yin Zhu, Ashley N Haddock

Cell Death Dis· April 2019

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Transgenic expression of cyclooxygenase-2 in pancreatic acinar cells induces chronic pancreatitis.
Haojie Huang, Jiaxiang Chen, Lisi Peng, Yao Yao, Defeng Deng, Ashley N Haddock

Am J Physiol Gastrointest Liver Physiol· January 2019

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Isolation, expression analysis and characterization of NEFA-interacting nuclear protein 30 and RING finger and SPRY domain containing 1 in skeletal muscle.
David S Waddell, Paige J Duffin, Ashley N Haddock, Virginia E Triplett, Jason J Saredy

Gene· January 2016

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