Publications by authors named "Ashley Menk"

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Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage.
Ansen H P Burr, Junyi Ji, Kadir Ozler, Heather L Mentrup, Onur Eskiocak, Ashley V Menk

Cell Mol Gastroenterol Hepatol· July 2023

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The effect of opioids on the efficacy of immunotherapy in recurrent/metastatic squamous cell carcinoma of the head and neck.
Nicole N Scheff, Marci L Nilsen, Jinhong Li, Alexandria L Harris, Rajesh Acharya, Ashley V Menk

Oral Oncol· May 2023

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Mesothelin-targeting T cells bearing a novel T cell receptor fusion construct (TRuC) exhibit potent antitumor efficacy against solid tumors.
Jian Ding, Sarah Guyette, Brett Schrand, Jessica Geirut, Holly Horton, Ashley Menk

Oncoimmunology· March 2023

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Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors.
Konstantinos Lontos, Yiyang Wang, Supriya K Joshi, Andrew T Frisch, McLane J Watson, Ashley V Menk

J Immunother Cancer· March 2023

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Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity.
Paolo D A Vignali, Kristin DePeaux, McLane J Watson, Chenxian Ye, B Rhodes Ford, Ashley V Menk

Nat Immunol· February 2023

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Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma.
Andrew W Hahn, Ashley V Menk, Dayana B Rivadeneira, Ryan C Augustin, Mingchu Xu

Clin Cancer Res· January 2023

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Checkpoint molecules coordinately restrain hyperactivated effector T cells in the tumor microenvironment.
Min Yang, Wenwen Du, Lixian Yi, Shaoxian Wu, Chunyan He, Ashley V Menk

Oncoimmunology· July 2021

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Tumor hypoxia is associated with resistance to PD-1 blockade in squamous cell carcinoma of the head and neck.
Dan P Zandberg, Ashley V Menk, Maria Velez, Daniel Normolle, Kristin DePeaux

J Immunother Cancer· May 2021

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Analyzing Melanoma Cell Oxygen Consumption and Extracellular Acidification Rates Using Seahorse Technology.
Ashley V Menk, Greg M Delgoffe

Methods Mol Biol· April 2021

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Metabolic support of tumour-infiltrating regulatory T cells by lactic acid.
McLane J Watson, Paolo D A Vignali, Steven J Mullett, Abigail E Overacre-Delgoffe, Ronal M Peralta, Ashley V Menk

Nature· March 2021

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Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion.
Nicole E Scharping, Dayana B Rivadeneira, Ashley V Menk, Paolo D A Vignali, B Rhodes Ford

Nat Immunol· February 2021

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mTORC2 Deficiency Alters the Metabolic Profile of Conventional Dendritic Cells.
Alicia R Watson, Helong Dai, Yawen Zheng, Ryosuke Nakano, Anastasios D Giannou, Ashley V Menk

Front Immunol· July 2020

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Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis.
Florian J Weisel, Steven J Mullett, Rebecca A Elsner, Ashley V Menk, Nikita Trivedi

Nat Immunol· March 2020

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Oncolytic Viruses Engineered to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor Clearance.
Dayana B Rivadeneira, Kristin DePeaux, Yiyang Wang, Aditi Kulkarni, Tracy Tabib, Ashley V Menk

Immunity· September 2019

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IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell.
Lulu Shao, Weizhou Hou, Nicole E Scharping, Frank P Vendetti, Rashmi Srivastava, Ashley V Menk

Cancer Immunol Res· August 2019

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Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8 T Cell-Derived Interferon-γ.
Chang Liu, Maria Chikina, Rahul Deshpande, Ashley V Menk, Ting Wang

Immunity· August 2019

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The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8 Memory T Cell Maintenance and Secondary Response to Infection.
Ann R Piccirillo, Eric J Hyzny, Lisa Y Beppu, Ashley V Menk, Callen T Wallace

J Immunol· July 2019

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Tumor-Derived α-Fetoprotein Suppresses Fatty Acid Metabolism and Oxidative Phosphorylation in Dendritic Cells.
Patricia M Santos, Ashley V Menk, Jian Shi, Allan Tsung, Greg M Delgoffe

Cancer Immunol Res· June 2019

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IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival.
Saikat Majumder, Nilesh Amatya, Shankar Revu, Chetan V Jawale, Dongwen Wu, Ashley Menk

Nat Immunol· May 2019

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Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4 T Cells.
Dana M Previte, Christina P Martins, Erin C O'Connor, Meghan L Marre, Gina M Coudriet, Ashley V Menk

Cell Rep· April 2019

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Tumor cell oxidative metabolism as a barrier to PD-1 blockade immunotherapy in melanoma.
Yana G Najjar, Ashley V Menk, Cindy Sander, Uma Rao, Arivarasan Karunamurthy

JCI Insight· March 2019

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Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted.
Jeremy S Tilstra, Lyndsay Avery, Ashley V Menk, Rachael A Gordon, Shuchi Smita

J Clin Invest· November 2018

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4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses.
Ashley V Menk, Nicole E Scharping, Dayana B Rivadeneira, Michael J Calderon, McLane J Watson

J Exp Med· April 2018

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IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation.
Shankar Revu, Jing Wu, Matthew Henkel, Natalie Rittenhouse, Ashley Menk

Cell Rep· March 2018

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Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions.
Ashley V Menk, Nicole E Scharping, Rebecca S Moreci, Xue Zeng, Cliff Guy

Cell Rep· February 2018

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