Publications by authors named "Asim A Beg"

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A model organism pipeline provides insight into the clinical heterogeneity of TARS1 loss-of-function variants.
Rebecca Meyer-Schuman, Allison R Cale, Jennifer A Pierluissi, Kira E Jonatzke, Young N Park, Asim A Beg

HGG Adv· July 2024

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Predictive modeling provides insight into the clinical heterogeneity associated with loss-of-function mutations.
Rebecca Meyer-Schuman, Allison R Cale, Jennifer A Pierluissi, Kira E Jonatzke, Young N Park, Asim A Beg

bioRxiv· March 2024

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An Intramolecular Salt Bridge Linking TDP43 RNA Binding, Protein Stability, and TDP43-Dependent Neurodegeneration.
Brittany N Flores, Xingli Li, Ahmed M Malik, Jose Martinez, Asim A Beg

Cell Rep· April 2019

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Dual phosphorylation of Ric-8A enhances its ability to mediate G protein α subunit folding and to stimulate guanine nucleotide exchange.
Makaía M Papasergi-Scott, Hannah M Stoveken, Lauren MacConnachie, Pui-Yee Chan, Meital Gabay, Asim A Beg

Sci Signal· May 2018

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A Rapid and Facile Pipeline for Generating Genomic Point Mutants in C. elegans Using CRISPR/Cas9 Ribonucleoproteins.
Harriet Prior, Lauren MacConnachie, Jose L Martinez, Georgina C B Nicholl, Asim A Beg

J Vis Exp· April 2018

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Highly Efficient, Rapid and Co-CRISPR-Independent Genome Editing in .
Harriet Prior, Ali K Jawad, Lauren MacConnachie, Asim A Beg

G3 (Bethesda)· November 2017

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Pharmacological characterization of the excitatory 'Cys-loop' GABA receptor family in Caenorhabditis elegans.
Georgina C B Nicholl, Ali K Jawad, Robert Weymouth, Haoming Zhang, Asim A Beg

Br J Pharmacol· May 2017

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Predicting the pathogenicity of aminoacyl-tRNA synthetase mutations.
Stephanie N Oprescu, Laurie B Griffin, Asim A Beg, Anthony Antonellis

Methods· January 2017

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The Rac-GAP alpha2-chimaerin regulates hippocampal dendrite and spine morphogenesis.
Chris M Valdez, Geoffrey G Murphy, Asim A Beg

Mol Cell Neurosci· September 2016

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Loss of function mutations in HARS cause a spectrum of inherited peripheral neuropathies.
Dana Safka Brozkova, Tine Deconinck, Laurie Beth Griffin, Andreas Ferbert, Jana Haberlova, Asim A Beg

Brain· August 2015

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α2-chimaerin is required for Eph receptor-class-specific spinal motor axon guidance and coordinate activation of antagonistic muscles.
Tzu-Jen Kao, Georgina C B Nicholl, Jamie A Johansen, Artur Kania, Asim A Beg

J Neurosci· February 2015

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Spillover transmission is mediated by the excitatory GABA receptor LGC-35 in C. elegans.
Meghan A Jobson, Chris M Valdez, Jann Gardner, L Rene Garcia, Erik M Jorgensen, Asim A Beg

J Neurosci· February 2015

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A loss-of-function variant in the human histidyl-tRNA synthetase (HARS) gene is neurotoxic in vivo.
Aimée Vester, Gisselle Velez-Ruiz, Heather M McLaughlin, , James R Lupski, Asim A Beg

Hum Mutat· January 2013

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Neuroscience: Angelman syndrome connections.
Peter Scheiffele, Asim A Beg

Nature· December 2010

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Protons act as a transmitter for muscle contraction in C. elegans.
Asim A Beg, Glen G Ernstrom, Paola Nix, M Wayne Davis, Erik M Jorgensen

Cell· January 2008

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alpha2-Chimaerin is an essential EphA4 effector in the assembly of neuronal locomotor circuits.
Asim A Beg, Julia E Sommer, John H Martin, Peter Scheiffele

Neuron· September 2007

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The diacylglycerol-binding protein alpha1-chimaerin regulates dendritic morphology.
Philip Buttery, Asim A Beg, Ben Chih, Arkady Broder, Carol A Mason

Proc Natl Acad Sci U S A· February 2006

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Neuroscience. SUMO wrestles the synapse.
Asim A Beg, Peter Scheiffele

Science· February 2006

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The GABA nervous system in C. elegans.
Kim Schuske, Asim A Beg, Erik M Jorgensen

Trends Neurosci· July 2004

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EXP-1 is an excitatory GABA-gated cation channel.
Asim A Beg, Erik M Jorgensen

Nat Neurosci· November 2003

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