Publications by authors named "Assunta Senatore"

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A Systematic Literature Review Exploring the Efficacy and Safety of Tadalafil and Sildenafil in Pulmonary Arterial Hypertension.
Rajan Saggar, Nora Rahhali, Assunta Senatore, Marinella Sandros, David Lopez

Pulm Circ· October 2025

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Macitentan and Tadalafil Combination Therapy in Patients with Pulmonary Arterial Hypertension and Cardiovascular Comorbidities: Real-World Evidence from OPUS and OrPHeUS.
Nick H Kim, Kelly M Chin, Vallerie V McLaughlin, Rose Ong, Gwen MacDonald, Assunta Senatore

Adv Ther· July 2025

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Macitentan and Tadalafil Combination Therapy in Incident and Prevalent Pulmonary Arterial Hypertension: Real-World Evidence from the OPUS/OrPHeUS Studies.
Kelly M Chin, Richard Channick, Nick H Kim, Gwen MacDonald, Rose Ong, Assunta Senatore

Adv Ther· November 2024

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Glial activation in prion diseases is selectively triggered by neuronal PrP.
Asvin K K Lakkaraju, Silvia Sorce, Assunta Senatore, Mario Nuvolone, Jingjing Guo

Brain Pathol· September 2022

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A conformational switch controlling the toxicity of the prion protein.
Karl Frontzek, Marco Bardelli, Assunta Senatore, Anna Henzi, Regina R Reimann

Nat Struct Mol Biol· August 2022

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Brain aging is faithfully modelled in organotypic brain slices and accelerated by prions.
Yingjun Liu, Assunta Senatore, Silvia Sorce, Mario Nuvolone, Jingjing Guo

Commun Biol· June 2022

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Author Correction: Brain aging is faithfully modelled in organotypic brain slices and accelerated by prions.
Yingjun Liu, Assunta Senatore, Silvia Sorce, Mario Nuvolone, Jingjing Guo

Commun Biol· June 2022

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The Epidemiology of Persons Living with Fontan in 2020 and Projections for 2030: Development of an Epidemiology Model Providing Multinational Estimates.
Leandra Plappert, Susan Edwards, Assunta Senatore, Angela De Martini

Adv Ther· February 2022

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The ultrastructure of infectious L-type bovine spongiform encephalopathy prions constrains molecular models.
Razieh Kamali-Jamil, Ester Vázquez-Fernández, Brian Tancowny, Vineet Rathod, Sara Amidian, Assunta Senatore

PLoS Pathog· June 2021

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PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice.
Clemens Messerschmidt, Marco Foddis, Sonja Blumenau, Susanne Müller, Kajetan Bentele, Assunta Senatore

Sci Rep· March 2021

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Soluble dimeric prion protein ligand activates Adgrg6 receptor but does not rescue early signs of demyelination in PrP-deficient mice.
Anna Henzi, Assunta Senatore, Asvin K K Lakkaraju, Claudia Scheckel, Jonas Mühle

PLoS One· January 2021

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Protective anti-prion antibodies in human immunoglobulin repertoires.
Assunta Senatore, Karl Frontzek, Marc Emmenegger, Andra Chincisan, Marco Losa

EMBO Mol Med· September 2020

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Isolation of infectious, non-fibrillar and oligomeric prions from a genetic prion disease.
Ilaria Vanni, Laura Pirisinu, Claudia Acevedo-Morantes, Razieh Kamali-Jamil, Vineet Rathod, Assunta Senatore

Brain· May 2020

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Inhibition of group-I metabotropic glutamate receptors protects against prion toxicity.
Despoina Goniotaki, Asvin K K Lakkaraju, Amulya N Shrivastava, Pamela Bakirci, Silvia Sorce, Assunta Senatore

PLoS Pathog· November 2017

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The biological function of the cellular prion protein: an update.
Marie-Angela Wulf, Assunta Senatore, Adriano Aguzzi

BMC Biol· May 2017

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Neurotoxic Antibodies against the Prion Protein Do Not Trigger Prion Replication.
Karl Frontzek, Manuela Pfammatter, Silvia Sorce, Assunta Senatore, Petra Schwarz

PLoS One· September 2016

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The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6.
Alexander Küffer, Asvin K K Lakkaraju, Amit Mogha, Sarah C Petersen, Kristina Airich, Assunta Senatore

Nature· August 2016

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Synaptic dysfunction in prion diseases: a trafficking problem?
Assunta Senatore, Elena Restelli, Roberto Chiesa

Int J Cell Biol· June 2014

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The inhibition of functional expression of calcium channels by prion protein demonstrates competition with α2δ for GPI-anchoring pathways.
Anita Alvarez-Laviada, Ivan Kadurin, Assunta Senatore, Roberto Chiesa, Annette C Dolphin

Biochem J· March 2014

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A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity.
Emiliano Biasini, Ursula Unterberger, Isaac H Solomon, Tania Massignan, Assunta Senatore

J Neurosci· February 2013

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Mutant PrP suppresses glutamatergic neurotransmission in cerebellar granule neurons by impairing membrane delivery of VGCC α(2)δ-1 Subunit.
Assunta Senatore, Simona Colleoni, Claudia Verderio, Elena Restelli, Raffaella Morini

Neuron· April 2012

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Mutant prion protein expression causes motor and memory deficits and abnormal sleep patterns in a transgenic mouse model.
Sara Dossena, Luca Imeri, Michela Mangieri, Anna Garofoli, Loris Ferrari, Assunta Senatore

Neuron· November 2008

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Non-infectious aggregates of the prion protein react with several PrPSc-directed antibodies.
Emiliano Biasini, M Esa Seegulam, Brianna N Patti, Laura Solforosi, Andrea Z Medrano, Assunta Senatore

J Neurochem· June 2008

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