Publications by authors named "Atul Akarte"

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Dual PI3Kδγ inhibition demonstrates potent anticancer effects in diffuse large B-cell lymphoma models: Discovery and preclinical characterization of LL-00084282.
Mahip K Verma, Charudatt Samant, Ramesh Kale, Sukanya Patra, Nilesh Mahajan, Atul Akarte

Biochem Biophys Res Commun· December 2022

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Discovery of a Potent and Selective PI3Kδ Inhibitor ()-2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl-4-quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models.
Manojkumar R Shukla, Sukanya Patra, Mahip Verma, Gayathri Sadasivam, Nirmal Jana, Atul Akarte

J Med Chem· December 2020

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An experimental assessment of toxic potential of nanoparticle preparation of heavy metals in streptozotocin induced diabetes.
Sonia Gandhi, B P Srinivasan, Atul Sureshrao Akarte

Exp Toxicol Pathol· November 2013

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Potential nephrotoxic effects produced by steroidal saponins from hydro alcoholic extract of Tribulus terrestris in STZ-induced diabetic rats.
Sonia Gandhi, B P Srinivasan, Atul S Akarte

Toxicol Mech Methods· September 2013

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Aliskiren improves insulin resistance and ameliorates diabetic renal vascular complications in STZ-induced diabetic rats.
Sonia Gandhi, Bp Srinivasan, Atul Sureshrao Akarte

J Renin Angiotensin Aldosterone Syst· March 2013

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Anti-inflammatory action of Tamarind seeds reduces hyperglycemic excursion by repressing pancreatic β-cell damage and normalizing SREBP-1c concentration.
Sushant S Sole, B P Srinivasan, Atul S Akarte

Pharm Biol· March 2013

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Vildagliptin selectively ameliorates GLP-1, GLUT4, SREBP-1c mRNA levels and stimulates β-cell proliferation resulting in improved glucose homeostasis in rats with streptozotocin-induced diabetes.
Atul Sureshrao Akarte, B P Srinivasan, Sonia Gandhi

J Diabetes Complications· January 2013

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Chronic DPP-IV inhibition with PKF-275-055 attenuates inflammation and improves gene expressions responsible for insulin secretion in streptozotocin induced diabetic rats.
Atul Sureshrao Akarte, B P Srinivasan, Sonia Gandhi, Sushant Sole

Eur J Pharm Sci· September 2012

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Effective blockade of RAAS by combination of aliskiren and olmesartan improves glucose homeostasis, glomerular filtration rate along with renal variables in streptozotocin induced diabetic rats.
Sonia Gandhi, B P Srinivasan, Atul Sureshrao Akarte

Eur J Pharm Sci· May 2012

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Relationships between the islets blood flow, nitric oxide, insulin, and cytosolic calcium in rat pancreatic islets: effects of DPP-IV inhibitor vildagliptin.
Atul Sureshrao Akarte, B P Srinivasan, Sonia Gandhi

Eur J Pharm Sci· April 2012

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A novel long acting DPP-IV inhibitor PKF-275-055 stimulates β-cell proliferation resulting in improved glucose homeostasis in diabetic rats.
Atul Sureshrao Akarte, B P Srinivasan, Sonia Gandhi

Biochem Pharmacol· January 2012

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Wound healing activity of Calotropis gigantea root bark in rats.
Pradeep T Deshmukh, Jennifer Fernandes, Akarte Atul, Emmanuel Toppo

J Ethnopharmacol· August 2009

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