Publications by authors named "Aurelien Jacob"

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Exonic knockout and knockin gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency.
Maria Carmina Castiello, Chiara Brandas, Samuele Ferrari, Simona Porcellini, Nicolò Sacchetti, Aurelien Jacob

Sci Transl Med· February 2024

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Unbiased assessment of genome integrity and purging of adverse outcomes at the target locus upon editing of CD4 T-cells for the treatment of Hyper IgM1.
Daniele Canarutto, Claudia Asperti, Valentina Vavassori, Simona Porcellini, Elisabetta Rovelli, Aurelien Jacob

EMBO J· December 2023

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Scalable GMP-compliant gene correction of CD4+ T cells with IDLV template functionally validated and .
Claudia Asperti, Daniele Canarutto, Simona Porcellini, Francesca Sanvito, Francesca Cecere, Aurelien Jacob

Mol Ther Methods Clin Dev· September 2023

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Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells.
Samuele Ferrari, Aurelien Jacob, Daniela Cesana, Marianne Laugel, Stefano Beretta

Cell Stem Cell· October 2022

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Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells.
Attya Omer-Javed, Gabriele Pedrazzani, Luisa Albano, Sherash Ghaus, Claire Latroche, Aurelien Jacob

Cell· June 2022

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Monobac System-A Single Baculovirus for the Production of rAAV.
Lionel Galibert, Aurélien Jacob, Adrien Savy, Yohann Dickx, Delphine Bonnin

Microorganisms· August 2021

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BAR-Seq clonal tracking of gene-edited cells.
Samuele Ferrari, Stefano Beretta, Aurelien Jacob, Davide Cittaro, Luisa Albano

Nat Protoc· June 2021

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Gene Editing of Hematopoietic Stem Cells: Hopes and Hurdles Toward Clinical Translation.
Samuele Ferrari, Valentina Vavassori, Daniele Canarutto, Aurelien Jacob, Maria Carmina Castiello

Front Genome Ed· March 2021

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Homologous Recombination Offers Advantages over Transposition-Based Systems to Generate Recombinant Baculovirus for Adeno-Associated Viral Vector Production.
Aurélien Jacob, Laurie Brun, Paloma Jiménez Gil, Lucie Ménard, Mohammed Bouzelha

Biotechnol J· January 2021

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Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking.
Samuele Ferrari, Aurelien Jacob, Stefano Beretta, Giulia Unali, Luisa Albano

Nat Biotechnol· November 2020

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Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response.
Giulia Schiroli, Anastasia Conti, Samuele Ferrari, Lucrezia Della Volpe, Aurelien Jacob

Cell Stem Cell· April 2019

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Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.
Giulia Schiroli, Samuele Ferrari, Anthony Conway, Aurelien Jacob, Valentina Capo

Sci Transl Med· October 2017

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