Publications by authors named "Austin Guo"

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Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid.
Ke Li, Xiu-Hua Yu, Anish R Maskey, Ibrahim Musa, Zhen-Zheng Wang, Austin Guo, Longgang Guo

Front Pharmacol· January 2023

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CYP4F2-Catalyzed Metabolism of Arachidonic Acid Promotes Stromal Cell-Mediated Immunosuppression in Non-Small Cell Lung Cancer.
Xuehan Chen, Yanzhuo Liu, Yang Wang, Chenlong Wang, Xuewei Chen, Austin M Guo

Cancer Res· November 2022

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Neutrophil-Derived Myeloperoxidase and Hypochlorous Acid Critically Contribute to 20-Hydroxyeicosatetraenoic Acid Increases that Drive Postischemic Angiogenesis.
Juan A Azcona, Samantha Tang, Elizabeth Berry, Frank F Zhang, Radha Garvey, Austin M Guo

J Pharmacol Exp Ther· June 2022

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ITLN1 inhibits tumor neovascularization and myeloid derived suppressor cells accumulation in colorectal carcinoma.
Li Chen, Xiao-Han Jin, Jie Luo, Jin-Ling Duan, Mu-Yan Cai, Austin Meng Guo

Oncogene· October 2021

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20-HETE synthesis inhibition promotes cerebral protection after intracerebral hemorrhage without inhibiting angiogenesis.
Xiaoning Han, Xiaochun Zhao, Xi Lan, Qian Li, Yufeng Gao, Austin M Guo

J Cereb Blood Flow Metab· August 2019

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CYP4A/20-HETE regulates ischemia-induced neovascularization via its actions on endothelial progenitor and preexisting endothelial cells.
Li Chen, Samantha Tang, Frank F Zhang, Victor Garcia, John R Falck, Austin M Guo

Am J Physiol Heart Circ Physiol· June 2019

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Eicosanoids: Emerging contributors in stem cell-mediated wound healing.
Elizabeth Berry, Yanzhou Liu, Li Chen, Austin M Guo

Prostaglandins Other Lipid Mediat· September 2017

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Intravenous Formulation of HET0016 Decreased Human Glioblastoma Growth and Implicated Survival Benefit in Rat Xenograft Models.
Meenu Jain, Nipuni-Dhanesha H Gamage, Meshal Alsulami, Adarsh Shankar, Bhagelu R Achyut, Austin Guo

Sci Rep· January 2017

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20-HETE contributes to ischemia-induced angiogenesis.
Li Chen, Gregory Joseph, Frank F Zhang, Huyen Nguyen, Houli Jiang, Austin M Guo

Vascul Pharmacol· August 2016

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Combination of vatalanib and a 20-HETE synthesis inhibitor results in decreased tumor growth in an animal model of human glioma.
Adarsh Shankar, Thaiz F Borin, Asm Iskander, Nadimpalli Rs Varma, Bhagelu R Achyut, Austin M Guo

Onco Targets Ther· March 2016

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HET0016, a selective inhibitor of 20-HETE synthesis, decreases pro-angiogenic factors and inhibits growth of triple negative breast cancer in mice.
Thaiz Ferraz Borin, Debora A P C Zuccari, Bruna V Jardim-Perassi, Lívia C Ferreira, A S M Iskander, Austin M Guo

PLoS One· August 2015

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Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion.
Hao Zheng, Ying Li, Yuzhong Wang, Haixia Zhao, Jing Zhang, Austin M Guo

Toxicol Appl Pharmacol· October 2014

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Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6.
Haixia Zhao, Xinhua Zhang, Xuewei Chen, Ying Li, Zunqiong Ke, Austin M Guo

Toxicol Appl Pharmacol· September 2014

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20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo.
Li Chen, Rachel Ackerman, Mohamed Saleh, Katherine H Gotlinger, Michael Kessler, Austin M Guo

J Pharmacol Exp Ther· March 2014

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Cardiovascular inflammation.
Miao Wang, Weijun Jin, Austin Meng Guo, Jane Stubbe

Mediators Inflamm· February 2014

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Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer.
Ying Li, Haixia Zhao, Yuzhong Wang, Hao Zheng, Wei Yu, Austin M Guo

Toxicol Appl Pharmacol· October 2013

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Elevated level of pro-inflammatory eicosanoids and EPC dysfunction in diabetic patients with cardiac ischemia.
Yossi Issan, Edith Hochhauser, Austin Guo, Katherine H Gotlinger, Ran Kornowski

Prostaglandins Other Lipid Mediat· January 2013

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20-HETE in neovascularization.
Li Chen, Rachel Ackerman, Austin M Guo

Prostaglandins Other Lipid Mediat· August 2012

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Role of 12-lipoxygenase in regulation of ovarian cancer cell proliferation and survival.
Austin M Guo, Xiuli Liu, Zaid Al-Wahab, Krishna Rao Maddippati, Rouba Ali-Fehmi

Cancer Chemother Pharmacol· November 2011

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Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.
Xiaohua Gao, Yongbo Liu, Dorrah Deeb, Ali S Arbab, Austin M Guo

Anticancer Res· November 2011

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Cytochrome P450 ω-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer.
Wei Yu, Li Chen, Yu-Qing Yang, John R Falck, Austin M Guo

Cancer Chemother Pharmacol· September 2011

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The cytochrome P450 4A/F-20-hydroxyeicosatetraenoic acid system: a regulator of endothelial precursor cells derived from human umbilical cord blood.
Austin M Guo, Branislava Janic, Ju Sheng, John R Falck, Richard J Roman

J Pharmacol Exp Ther· August 2011

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Human cord blood-derived AC133+ progenitor cells preserve endothelial progenitor characteristics after long term in vitro expansion.
Branislava Janic, Austin M Guo, A S M Iskander, Nadimpalli Ravi S Varma, Alfonso G Scicli

PLoS One· February 2010

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20-HETE can act as a nonhypoxic regulator of HIF-1alpha in human microvascular endothelial cells.
Austin M Guo, Gloria Scicli, Ju Sheng, John C Falck, Paul A Edwards

Am J Physiol Heart Circ Physiol· August 2009

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Expression of CYP4A1 in U251 human glioma cell induces hyperproliferative phenotype in vitro and rapidly growing tumors in vivo.
Austin M Guo, Ju Sheng, Gloria M Scicli, Ali S Arbab, Norman L Lehman

J Pharmacol Exp Ther· October 2008

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