Publications by authors named "Austin Klein"

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Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cycle.
Mushtaq A Nengroo, Austin T Klein, Heather S Carr, Olivia Vidal-Cruchez, Umakant Sahu

Mol Cell· November 2025

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Design and Characterization of 4D-710, an Aerosolized Gene Therapy for Cystic Fibrosis Lung Disease.
Melissa A Calton, Roxanne H Croze, Theodore H Sullivan, Sara A Collins, Sarah Tucker, Austin Klein

Am J Respir Cell Mol Biol· October 2025

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Succinate dehydrogenase activity supports de novo purine synthesis.
Mushtaq A Nengroo, Austin T Klein, Heather S Carr, Olivia Vidal-Cruchez, Umakant Sahu

bioRxiv· March 2025

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Design and Characterization of a Novel Intravitreal Dual-Transgene Genetic Medicine for Neovascular Retinopathies.
Melissa A Calton, Roxanne H Croze, Christian Burns, Ghezal Beliakoff, Tandis Vazin, Austin Klein

Invest Ophthalmol Vis Sci· December 2024

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Tight regulation of a nuclear HAPSTR1-HUWE1 pathway essential for mammalian life.
David R Amici, Sammy Alhayek, Austin T Klein, Yi-Zhi Wang, Anika P Wilen

Life Sci Alliance· May 2024

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Addicted to proteostasis: How KRAS-driven cancers acquire resistance to clinical KRAS inhibitors.
Austin T Klein, Marc L Mendillo

Cell Chem Biol· November 2023

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Insight into how patients with prostate cancer interpret and communicate genetic test results: implications for families.
Amy E Leader, Joanna Mercado, Austin Klein, Colette Hyatt, Laura Gross

J Community Genet· December 2022

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