Publications by authors named "Avneesh Singh"

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Transplantation of a genetically modified porcine heart into a live human.
Bartley P Griffith, Alison Grazioli, Avneesh K Singh, Andy Tully, Javier Galindo

Nat Med· February 2025

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Genetically engineered pig heart transplantation in non-human primates.
Avneesh K Singh, Corbin E Goerlich, Tianshu Zhang, Billeta Lewis, Alena Hershfeld

Commun Med (Lond)· January 2025

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Possible causes of graft dysfunction in cardiac xenotransplantation - Authors' reply.
Muhammad M Mohiuddin, Andy Tully, Avneesh K Singh, Javier Galindo, Bartley P Griffith

Lancet· June 2024

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Comprehensive Multimodal Phenotyping as a Novel Method Evaluating Xenograft Rejection.
Muhammad M Mohiuddin, Andy Tully, Javier Galindo, Avneesh K Singh

Transplantation· May 2024

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The Young Investigator Committee of the International Xenotransplantation Association-Perspective of advancements in the field in 2023.
Corbin E Goerlich, Shani S Kamberi, Joseph Ladowski, Antonio Citro, Margaret Connolly, Avneesh K Singh

Xenotransplantation· February 2024

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Genetic Engineering of Donor Pig for the First Human Cardiac Xenotransplantation: Combatting Rejection, Coagulopathy, Inflammation, and Excessive Growth.
Shreya Singireddy, Andy Tully, Javier Galindo, David Ayares, Avneesh K Singh

Curr Cardiol Rep· November 2023

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A Standardized Approach to Orthotopic (Life-supporting) Porcine Cardiac Xenotransplantation in a Nonhuman Primate Model.
Corbin E Goerlich, Bartley P Griffith, Aakash Shah, John A Treffalls, Tianshu Zhang, Avneesh K Singh

Transplantation· August 2023

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CD40-CD40L Blockade: Update on Novel Investigational Therapeutics for Transplantation.
Avneesh K Singh, Corbin E Goerlich, Tianshu Zhang, Billeta G T Lewis, Alena Hershfeld

Transplantation· July 2023

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Graft dysfunction in compassionate use of genetically engineered pig-to-human cardiac xenotransplantation: a case report.
Muhammad M Mohiuddin, Avneesh K Singh, Linda Scobie, Corbin E Goerlich, Alison Grazioli

Lancet· July 2023

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The growth of xenotransplanted hearts can be reduced with growth hormone receptor knockout pig donors.
Corbin E Goerlich, Bartley Griffith, Peter Hanna, Susie N Hong, David Ayares, Avneesh K Singh

J Thorac Cardiovasc Surg· February 2023

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Preclinical rationale and current pathways to support the first human clinical trials in cardiac xenotransplantation.
Muhammad M Mohiuddin, Avneesh K Singh, Corbin E Goerlich

Hum Immunol· January 2023

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The road to the first FDA-approved genetically engineered pig heart transplantation into human.
Avneesh K Singh, Bartley P Griffith, Corbin E Goerlich, David Ayares, Muhammad M Mohiuddin

Xenotransplantation· September 2022

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The immunobiology and clinical use of genetically engineered porcine hearts for cardiac xenotransplantation.
Corbin E Goerlich, Avneesh K Singh, Bartley P Griffith, Muhammad M Mohiuddin

Nat Cardiovasc Res· August 2022

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Genetically Modified Porcine-to-Human Cardiac Xenotransplantation.
Bartley P Griffith, Corbin E Goerlich, Avneesh K Singh, Martine Rothblatt, Christine L Lau

N Engl J Med· July 2022

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Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months.
Muhammad M Mohiuddin, Corbin E Goerlich, Avneesh K Singh, Tianshu Zhang, Ivan Tatarov

Xenotransplantation· May 2022

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Cardiac Xenotransplantation: Progress in Preclinical Models and Prospects for Clinical Translation.
Avneesh K Singh, Corbin E Goerlich, Aakash M Shah, Tianshu Zhang, Ivan Tatarov

Transpl Int· April 2022

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An intrinsic link to an extrinsic cause of cardiac xenograft growth after xenotransplantation: Commentary (in response to): Zaman, R. et al. Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress. Immunity 54, 2057-2071.e6 (2021).: Commentary (in response to): Zaman, R. et al. Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress. Immunity 54, 2057-2071.e6 (2021).
Corbin E Goerlich, Avneesh Singh, John A Treffalls, Bartley Griffith, David Ayares

Xenotransplantation· January 2022

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Blood Cardioplegia Induction, Perfusion Storage and Graft Dysfunction in Cardiac Xenotransplantation.
Corbin E Goerlich, Bartley Griffith, Avneesh K Singh, Mohamed Abdullah, Shreya Singireddy

Front Immunol· October 2021

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Heterotopic Porcine Cardiac Xenotransplantation in the Intra-Abdominal Position in a Non-Human Primate Model.
Corbin E Goerlich, Laura DiChiacchio, Tianshu Zhang, Avneesh K Singh, Billeta Lewis

Sci Rep· July 2020

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Early Experience With Preclinical Perioperative Cardiac Xenograft Dysfunction in a Single Program.
Laura DiChiacchio, Avneesh K Singh, Billeta Lewis, Tianshu Zhang, Naomi Hardy

Ann Thorac Surg· May 2020

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Intra-Abdominal Heterotopic Cardiac Xenotransplantation: Pearls and Pitfalls.
Laura DiChiacchio, Avneesh K Singh, Joshua L Chan, Nicole M Shockcor, Tianshu Zhang

Front Cardiovasc Med· July 2019

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A rare case of diffuse intracranial aspergillosis masquerading as skull base meningioma in an immunocompetent patient.
Ishita Pant, Sujata Chaturvedi, Avneesh Kumar Singh, Gurbachan Singh, Sadhna Tiwari

Clin Neuropathol· April 2019

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Cardiac xenografts show reduced survival in the absence of transgenic human thrombomodulin expression in donor pigs.
Avneesh K Singh, Joshua L Chan, Laura DiChiacchio, Naomi L Hardy, Philip C Corcoran

Xenotransplantation· March 2019

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Xenotransplantation: A Step Closer to Clinical Reality?
Muhammad M Mohiuddin, Laura DiChiacchio, Avneesh K Singh, Bartley P Griffith

Transplantation· March 2019

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Consideration of appropriate clinical applications for cardiac xenotransplantation.
Joshua L Chan, Justin G Miller, Avneesh K Singh, Keith A Horvath, Philip C Corcoran

Clin Transplant· August 2018

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