Publications by authors named "Axel B Janssen"

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CRISPRi-seq in Haemophilus influenzae reveals genome-wide and medium-specific growth determinants.
Celia Gil-Campillo, Johann Mignolet, Asier Domínguez-San Pedro, Beatriz Rapún-Araiz, Axel B Janssen

PLoS Pathog· October 2025

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Long-term effects of influenza and Bacille Calmette-Guérin vaccination on systemic inflammation.
Priya A Debisarun, Rutger J Röring, Özlem Bulut, Thijs Ten Doesschate, Thomas W van der Vaart, Axel B Janssen

Clin Transl Immunology· September 2025

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Make-or-break prime editing for genome engineering in Streptococcus pneumoniae.
Monica Rengifo-Gonzalez, Maria-Vittoria Mazzuoli, Axel B Janssen, Anne-Stéphanie Rueff, Jessica Burnier

Nat Commun· April 2025

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PneumoBrowse 2: an integrated visual platform for curated genome annotation and multiomics data analysis of Streptococcus pneumoniae.
Axel B Janssen, Paddy S Gibson, Afonso M Bravo, Vincent de Bakker, Jelle Slager

Nucleic Acids Res· January 2025

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An efficient -inducible CRISPR interference system for group A genetic analysis and pathogenesis studies.
Elisabet Bjånes, Alexandra Stream, Axel B Janssen, Paddy S Gibson, Afonso M Bravo

mBio· August 2024

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OmpR facilitates lung infection through transcriptional regulation of key virulence factors.
Axel B Janssen, Vincent de Bakker, Rieza Aprianto, Vincent Trebosc, Christian Kemmer

Microbiol Spectr· January 2024

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Colistin resistance mutations in phoQ can sensitize Klebsiella pneumoniae to IgM-mediated complement killing.
Sjors P A van der Lans, Manon Janet-Maitre, Frerich M Masson, Kimberly A Walker, Dennis J Doorduijn, Axel B Janssen

Sci Rep· August 2023

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BCG Vaccination of Health Care Workers Does Not Reduce SARS-CoV-2 Infections nor Infection Severity or Duration: a Randomized Placebo-Controlled Trial.
Juana Claus, Thijs Ten Doesschate, Cheyenne Gumbs, Cornelis H van Werkhoven, Thomas W van der Vaart, Axel B Janssen

mBio· April 2023

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Efficacy of BCG Vaccination Against Respiratory Tract Infections in Older Adults During the Coronavirus Disease 2019 Pandemic.
Simone J C F M Moorlag, Esther Taks, Thijs Ten Doesschate, Thomas W van der Vaart, Axel B Janssen

Clin Infect Dis· August 2022

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Erratum for Janssen et al., "Evolution of Colistin Resistance in the Klebsiella pneumoniae Complex Follows Multiple Evolutionary Trajectories with Variable Effects on Fitness and Virulence Characteristics".
Axel B Janssen, Dennis J Doorduijn, Grant Mills, Malbert R C Rogers, Marc J M Bonten

Antimicrob Agents Chemother· June 2021

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Harder, better, faster, stronger: Colistin resistance mechanisms in Escherichia coli.
Axel B Janssen, Willem van Schaik

PLoS Genet· January 2021

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Evolution of Colistin Resistance in the Klebsiella pneumoniae Complex Follows Multiple Evolutionary Trajectories with Variable Effects on Fitness and Virulence Characteristics.
Axel B Janssen, Dennis J Doorduijn, Grant Mills, Malbert R C Rogers, Marc J M Bonten

Antimicrob Agents Chemother· December 2020

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Microevolution of acquired colistin resistance in Enterobacteriaceae from ICU patients receiving selective decontamination of the digestive tract.
Axel B Janssen, Denise van Hout, Marc J M Bonten, Rob J L Willems, Willem van Schaik

J Antimicrob Chemother· November 2020

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Two Randomized Controlled Trials of Bacillus Calmette-Guérin Vaccination to reduce absenteeism among health care workers and hospital admission by elderly persons during the COVID-19 pandemic: A structured summary of the study protocols for two randomised controlled trials.
Thijs Ten Doesschate, Simone J C F M Moorlag, Thomas W van der Vaart, Esther Taks, Priya Debisarun, Axel B Janssen

Trials· June 2020

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Correction to: Two Randomized Controlled Trials of Bacillus Calmette-Guérin Vaccination to reduce absenteeism among health care workers and hospital admission by elderly persons during the COVID-19 pandemic: A structured summary of the study protocols for two randomised controlled trials.
Thijs Ten Doesschate, Simone J C F M Moorlag, Thomas W van der Vaart, Esther Taks, Priya Debisarun, Axel B Janssen

Trials· June 2020

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Nonclonal Emergence of Colistin Resistance Associated with Mutations in the BasRS Two-Component System in Escherichia coli Bloodstream Isolates.
Axel B Janssen, Toby L Bartholomew, Natalia P Marciszewska, Marc J M Bonten, Rob J L Willems

mSphere· March 2020

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The added value of the selective SuperPolymyxin™ medium in detecting rectal carriage of Gram-negative bacteria with acquired colistin resistance in intensive care unit patients receiving selective digestive decontamination.
Denise van Hout, Axel B Janssen, Rob J Rentenaar, Judith P M Vlooswijk, C H Edwin Boel

Eur J Clin Microbiol Infect Dis· February 2020

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A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.
Yvonne Vercoulen, Yasushi Kondo, Jeffrey S Iwig, Axel B Janssen, Katharine A White

Elife· September 2017

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Genomic Characterization of Colistin Heteroresistance in Klebsiella pneumoniae during a Nosocomial Outbreak.
Teysir Halaby, Emre Kucukkose, Axel B Janssen, Malbert R C Rogers, Dennis J Doorduijn

Antimicrob Agents Chemother· November 2016

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Arming oncolytic viruses to leverage antitumor immunity.
Tanja D de Gruijl, Axel B Janssen, Victor W van Beusechem

Expert Opin Biol Ther· July 2015

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