Publications by authors named "BC Pearce"

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Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1.
Andrew P Degnan, Godwin K Kumi, Christopher W Allard, Erika V Araujo, Walter L Johnson, Bradley C Pearce

ACS Med Chem Lett· March 2021

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Patient satisfaction with nurse-led end of treatment telephone consultation for breast cancer during COVID-19 pandemic.
Alexander Thomas Schuster-Bruce, Harry Alexander Raban Middleton, Caroline Macpherson, Belinda C S Pearce, Abigail Evans

Breast J· January 2021

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Fertility preservation for women undergoing breast cancer treatment: A postcode lottery?
Isabella Dash, Belinda C S Pearce, Sarah Armstrong, Christobel Saunders, Allan Pacey

Breast J· October 2020

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Reply to: Evidence-based surgery to realize a successful extreme oncoplastic breast conservation.
Belinda C S Pearce, Roanne N Fiddes, Nirmala Paramanathan, Natalie Chand, Siobhan A M Laws

Eur J Surg Oncol· May 2020

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Extreme oncoplastic conservation is a safe new alternative to mastectomy.
Belinda C S Pearce, Roanne N Fiddes, Nirmala Paramanathan, Natalie Chand, Siobhan A M Laws

Eur J Surg Oncol· January 2020

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Discovery of the Human Immunodeficiency Virus Type 1 (HIV-1) Attachment Inhibitor Temsavir and Its Phosphonooxymethyl Prodrug Fostemsavir.
Tao Wang, Yasu Ueda, Zhongxing Zhang, Zhiwei Yin, John Matiskella, Bradley C Pearce

J Med Chem· July 2018

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BMS-986163, a Negative Allosteric Modulator of GluN2B with Potential Utility in Major Depressive Disorder.
Lawrence R Marcin, Jayakumar Warrier, Srinivasan Thangathirupathy, Jianliang Shi, George N Karageorge, Bradley C Pearce

ACS Med Chem Lett· May 2018

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Triazolopyridine ethers as potent, orally active mGlu positive allosteric modulators for treating schizophrenia.
Mendi A Higgins, Lawrence R Marcin, F Christopher Zusi, Robert Gentles, Min Ding, Bradley C Pearce

Bioorg Med Chem· January 2017

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Identification of small molecules that selectively inhibit diacylglycerol lipase-α activity.
Kingsley K Appiah, Yuval Blat, Barbara J Robertson, Bradley C Pearce, Donna L Pedicord

J Biomol Screen· April 2014

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HCV NS5A replication complex inhibitors. Part 4. Optimization for genotype 1a replicon inhibitory activity.
Denis R St Laurent, Michael H Serrano-Wu, Makonen Belema, Min Ding, Hua Fang, Bradley C Pearce

J Med Chem· March 2014

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Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers.
Samuel W Gerritz, Christopher Cianci, Sean Kim, Bradley C Pearce, Carol Deminie

Proc Natl Acad Sci U S A· September 2011

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Molecular characterization and identification of surrogate substrates for diacylglycerol lipase α.
Donna L Pedicord, Michael J Flynn, Caroline Fanslau, Maricar Miranda, Lisa Hunihan, Bradley C Pearce

Biochem Biophys Res Commun· August 2011

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Inhibitors of HIV-1 attachment. Part 3: A preliminary survey of the effect of structural variation of the benzamide moiety on antiviral activity.
Nicholas A Meanwell, Owen B Wallace, Henry Wang, Milind Deshpande, Bradley C Pearce

Bioorg Med Chem Lett· September 2009

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E-novo: an automated workflow for efficient structure-based lead optimization.
Bradley C Pearce, David R Langley, Jia Kang, Hongwei Huang, Amit Kulkarni

J Chem Inf Model· July 2009

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Inhibitors of HIV-1 attachment. Part 2: An initial survey of indole substitution patterns.
Nicholas A Meanwell, Owen B Wallace, Haiquan Fang, Henry Wang, Milind Deshpande, Bradley C Pearce

Bioorg Med Chem Lett· April 2009

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Respiratory syncytial virus fusion inhibitors. Part 6: an examination of the effect of structural variation of the benzimidazol-2-one heterocycle moiety.
Keith D Combrink, H Belgin Gulgeze, Jan W Thuring, Kuo-Long Yu, Rita L Civiello, Bradley C Pearce

Bioorg Med Chem Lett· September 2007

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An empirical process for the design of high-throughput screening deck filters.
Bradley C Pearce, Michael J Sofia, Andrew C Good, Dieter M Drexler, David A Stock

J Chem Inf Model· June 2006

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Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo.
Kuo-Long Yu, Xiangdong Alan Wang, Rita L Civiello, Ashok K Trehan, Bradley C Pearce

Bioorg Med Chem Lett· March 2006

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Respiratory syncytial virus inhibitors. Part 2: Benzimidazol-2-one derivatives.
Kuo-Long Yu, Yi Zhang, Rita L Civiello, Ashok K Trehan, Bradley C Pearce

Bioorg Med Chem Lett· March 2004

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Salicylamide inhibitors of influenza virus fusion.
K D Combrink, H B Gulgeze, K L Yu, B C Pearce, A K Trehan

Bioorg Med Chem Lett· August 2000

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1,2-Benzisothiazol-3-one 1,1-dioxide inhibitors of human mast cell tryptase.
K D Combrink, H B Gülgeze, N A Meanwell, B C Pearce, P Zulan

J Med Chem· November 1998

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Dietary alpha-tocopherol attenuates the impact of gamma-tocotrienol on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in chickens.
A A Qureshi, B C Pearce, R M Nor, A Gapor, D M Peterson

J Nutr· February 1996

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Structure Determination of the Products from the Acid-Catalyzed Condensation of Indole with Acetone.
Wayland E. Noland, Michael J. Konkel, Lisa M. C. Konkel, Bradley C. Pearce, Charles L. Barnes

J Org Chem· January 1996

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Response of hypercholesterolemic subjects to administration of tocotrienols.
A A Qureshi, B A Bradlow, L Brace, J Manganello, D M Peterson, B C Pearce

Lipids· December 1995

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Structure of the scalar mesons f0(980) and a0(980).
G Janssen, BC Pearce, K Holinde, J Speth

Phys Rev D Part Fields· September 1995

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