Publications by authors named "Baoding Zhang"

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Discovery of highly selective and potent HPK1 inhibitors for cancer immunotherapy.
Wei Huang, Xiao-E Yan, Jingwen Wang, Yidan Zhang, Shan Li, Baoding Zhang, Jianming Zhang

Eur J Med Chem· January 2026

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Discovery of an ALK degrader for lorlatinib-resistant compound mutations.
Fei Gao, Zhenhua Wu, Anqi Lin, Xinyu Wu, Baoding Zhang, Jianming Zhang

Eur J Med Chem· October 2025

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METTL10-Mediated PIAS3 Methylation Links Purine Metabolism to Gastric Cancer Progression.
Jinshui Tan, Huiwen Zhou, Jingsong Ma, Chensong Zhang, Yuhua Tan, Baoding Zhang

Adv Sci (Weinh)· October 2025

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Inhibiting NEDD4 in triple-negative breast cancer cells reprograms tumor immune microenvironment via the β-TrCP/YAP/ECM axis.
Nan Su, Wenhua Lian, Baoding Zhang, Yuan Tian, Linying Li

Cell Rep Med· October 2025

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A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2.
Yankai Chu, Shishuang Chen, Mingyang Yang, Yin Chen, Huiling Fang, Baoding Zhang, Lulu Zhang

Nat Biotechnol· September 2025

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Lithocholic acid phenocopies anti-ageing effects of calorie restriction.
Qi Qu, Yan Chen, Yu Wang, Shating Long, Weiche Wang, Cixiong Zhang, Baoding Zhang, Chen-Song Zhang

Nature· July 2025

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Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing.
Qi Qu, Yan Chen, Yu Wang, Weiche Wang, Shating Long, Cixiong Zhang, Baoding Zhang, Chen-Song Zhang

Nature· July 2025

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Author Correction: Lithocholic acid phenocopies anti-ageing effects of calorie restriction.
Qi Qu, Yan Chen, Yu Wang, Shating Long, Weiche Wang, Cixiong Zhang, Baoding Zhang, Chen-Song Zhang

Nature· February 2025

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AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine.
Mengqi Li, Yu Wang, Xiaoyan Wei, Wei-Feng Cai, Jianfeng Wu, Cixiong Zhang, Baoding Zhang, Chen-Song Zhang

Cell Res· October 2024

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Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis.
Wen-Juan Li, Ying Huang, Yi-An Lin, Bao-Ding Zhang, Mei-Yan Li

Cell Rep· November 2023

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Rational design of a polysaccharide-based viral mimicry nanocomplex for potent gene silencing in inflammatory tissues.
Han Gao, Shiqi Wang, Qiang Long, Ruoyu Cheng, Wenhua Lian, Baoding Zhang

J Control Release· May 2023

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Samarium-Based Turn-Off Fluorescence Sensor for Sensitive and Selective Detection of Quinolinic Acid in Human Urine and Serum.
Bao-Ding Zhang, Bing Liu, Yu-Xing Yin, Ling Xu

Inorg Chem· January 2023

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The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.
Chen-Song Zhang, Mengqi Li, Yu Wang, Xiaoyang Li, Yue Zong, Mingliang Zhang, Baoding Zhang, Cixiong Zhang, Lei Zhang

Nat Metab· October 2022

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PIKfyve inhibitors against SARS-CoV-2 and its variants including Omicron.
Jingyi Su, Jing Zheng, Wei Huang, Yali Zhang, Cairui Lv, Baoding Zhang, Jianming Zhang

Signal Transduct Target Ther· May 2022

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Low-dose metformin targets the lysosomal AMPK pathway through PEN2.
Teng Ma, Xiao Tian, Baoding Zhang, Mengqi Li, Yu Wang, Cixiong Zhang, Lei Zhang, Mingliang Zhang, Chen-Song Zhang

Nature· March 2022

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A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC.
Yue Lu, Zhenzhen Fan, Su-Jie Zhu, Xiaoxing Huang, Zhongji Zhuang, Ting Zhang, Jingfang Zhang, Baoding Zhang, Jianming Zhang

EMBO Mol Med· January 2022

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Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant.
Xiaoyang Li, Jingyi Su, Yanru Yang, Wenhua Lian, Zhou Deng, Baoding Zhang

Eur J Med Chem· December 2020

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Discovery of methyl 3-((2-((1-(dimethylglycyl)-5-methoxyindolin-6-yl)amino)-5-(trifluoro-methyl) pyrimidin-4-yl)amino)thiophene-2-carboxylate as a potent and selective polo-like kinase 1 (PLK1) inhibitor for combating hepatocellular carcinoma.
Zhou Deng, Guyue Chen, Shuang Liu, Yunzhan Li, Jiaji Zhong, Baoding Zhang

Eur J Med Chem· November 2020

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Heterogeneous gold catalysts for selective hydrogenation: from nanoparticles to atomically precise nanoclusters.
Jianbo Zhao, Liming Ge, Haifeng Yuan, Yingfan Liu, Yanghai Gui, Baoding Zhang

Nanoscale· June 2019

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