Publications by authors named "Baotran Ho"

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Down-regulation of ALDH1A3, CD44 or MDR1 sensitizes resistant cancer cells to FAK autophosphorylation inhibitor Y15.
Vita Golubovskaya, Shalana O'Brien, Baotran Ho, Melissa Heffler, Jeffrey Conroy

J Cancer Res Clin Oncol· September 2015

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Focal adhesion kinase regulates expression of thioredoxin-interacting protein (TXNIP) in cancer cells.
Baotran Ho, Grace Huang, Vita M Golubovskaya

Anticancer Agents Med Chem· January 2014

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The microarray gene profiling analysis of glioblastoma cancer cells reveals genes affected by FAK inhibitor Y15 and combination of Y15 and temozolomide.
Grace Huang, Baotran Ho, Jeffrey Conroy, Song Liu, Hu Qiang

Anticancer Agents Med Chem· January 2014

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MiR-138 and MiR-135 directly target focal adhesion kinase, inhibit cell invasion, and increase sensitivity to chemotherapy in cancer cells.
Vita M Golubovskaya, Brittany Sumbler, Baotran Ho, Michael Yemma, William G Cance

Anticancer Agents Med Chem· January 2014

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Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex.
Vita M Golubovskaya, Baotran Ho, Jeffrey Conroy, Song Liu, Dan Wang

Cancers (Basel)· January 2014

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Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth.
Vita M Golubovskaya, Baotran Ho, Min Zheng, Andrew Magis, David Ostrov

BMC Cancer· July 2013

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A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.
Vita M Golubovskaya, Nadia L Palma, Min Zheng, Baotran Ho, Andrew Magis

Anticancer Agents Med Chem· May 2013

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Mitoxantrone targets the ATP-binding site of FAK, binds the FAK kinase domain and decreases FAK, Pyk-2, c-Src, and IGF-1R in vitro kinase activities.
Vita M Golubovskaya, Baotran Ho, Min Zheng, Andrew Magis, David Ostrov

Anticancer Agents Med Chem· May 2013

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Pharmacologic blockade of FAK autophosphorylation decreases human glioblastoma tumor growth and synergizes with temozolomide.
Vita M Golubovskaya, Grace Huang, Baotran Ho, Michael Yemma, Carl D Morrison

Mol Cancer Ther· February 2013

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A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl)-3, 5, 7-triaza-1-azoniatricyclo [3.3.1.1(3,7)]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo.
Vita M Golubovskaya, Sheila Figel, Baotran T Ho, Christopher P Johnson, Michael Yemma

Carcinogenesis· May 2012

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Nanog increases focal adhesion kinase (FAK) promoter activity and expression and directly binds to FAK protein to be phosphorylated.
Baotran Ho, Gretchen Olson, Sheila Figel, Irwin Gelman, William G Cance

J Biol Chem· May 2012

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